Patients and Health Staff of Cancer Centres During the Covid-19 Pandemic

Sponsor
Institut Cancerologie de l'Ouest
Study ID
NCT04421625
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Diagnostic test for SARS-Cov2 for patients and health staff — DIAGNOSTIC_TEST
    Diagnostic test for SARS-CoV2 : * Blood test to analyse the IgG and IgM with an immediate qualitative analysis (serological test) and a differed quantitative analysis (ELISA test) * Results of nasal swab that will allow extracting the RNA and realizing a RT-PCR (only if the participants present symptoms). It will be obtained by standard local laboratories. * Questionnaires (based on serology, clinic, economy (socio-demographic and lifestyle questionnaire) and epidemiology)

Study Details

The Covid-19 has, in a few weeks, made the world tremble: the number of deaths (mainly elderly and / or co-morbid) continues to increase, the confinement causes the collapsing of the economy and the decline of relationships inter-human. The data are too fragmented and the disease too recent to know its repercussions on the 3 million French people who have or have had cancer. The investigators would like, in 3 populations: \* patients in treatment, \* or in follow-up and \* health personnel, to constitute a large prospective and longitudinal database of data: i / serological: humoral response, test performance, monitoring of serum immunoglobulin levels , reinfection threshold,…; ii / clinical: incidence, severity, mortality and their favorable factors impact of cancer treatment on Covid-19 infection and modification of the quality of oncological care in the context. In parallel, on a more limited sample of establishments, it will be : \* appreciate the economic and functional repercussions, \* will try to find out about the infection modalities in patients and health personnel and \* will appreciate the levels of anxiety and depression to which health staff are subject.

Key Dates

Start date
Jun 15, 2020
Status verified
Jul 2023
Primary completion
Jun 28, 2022
Completion
Jun 28, 2022

Study Design

Enrollment
1,102 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING

Arms

  • Experimental: Diagnostic test for SARS-Cov2 for patients and health staff
    * Blood test (rapid serology (immediate analysis), ELISA serology (differed analysis on frozen sample), genotyping of FCGR2A and FCGR3A gens) * Nasal swab test (only if the patient has symptoms) * Questionnaires

Primary Outcome Measure

Number and Severity of Confirmed COVID-19 Infections Among Cancer Centre Staff and Patients at 12 Months [ Time Frame: 12 months ]

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