Surufatinib or Surufatinib Combined With Vinorelbine for Non-Small Cell Lung Cancer
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
- Study ID
- NCT04922658
- Phase
- PHASE2
- Status
- Active Not Recruiting
Conditions
- Advanced Non-Small Cell Lung Cancer
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Surufatinib — DRUGSurufatinib,300mg, qd, po, 21 days for a cycle; continuous administration until PD, death or intolerable toxicity.
- Surufatinib Plus Vinorelbine — DRUGSurufatinib, 250mg, qd, po; Plus Vinorelbine, 20 mg, every 2 days; 21days for a cycle; continuous administration until PD, death or intolerable toxicity.
Study Details
A phase II study to assess the efficacy and safety of Surufatinib or Surufatinib combined with Vinorelbine as third-line and posterior line treatment in patients with NSCLC
Key Dates
- First listed
- Jun 10, 2021
- Start date
- Jun 3, 2020
- Status verified
- Jul 2026
- Primary completion
- Dec 1, 2025
- Completion
- Dec 31, 2026
Study Design
- Enrollment
- 76 participants (actual)
- Allocation
- NON_RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: Surufatinib
- Experimental: Surufatinib plus Vinorelbine
Primary Outcome Measure
Progression-free survival (PFS) [ Time Frame: up to 12 months ]
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