Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC)

Part of paid clinical trials in Charlestown, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT05092516
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Active tDCS — DEVICE
    2 mA of anodal stimulation will be applied to the left prefrontal cortex over the F3 electrode based on the International 10-10 EEG system.
  • Sham tDCS — DEVICE
    Sham stimulation will be applied to the left prefrontal cortex over the F3 electrode.

Study Details

The main goal of this study is to improve dysexecutive symptoms (e.g., sustained attention, processing speed) in patients exhibiting post-acute sequelae of COVID-19 (PASC) through home-based transcranial direct current stimulation (tDCS), a noninvasive method that uses low intensity electric currents delivered to the brain through stimulation electrodes on the scalp.

Key Dates

Start date
Jun 7, 2022
Status verified
Nov 2025
Primary completion
Mar 13, 2025
Completion
Jun 15, 2026

Study Design

Enrollment
31 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Active tDCS
    This group will receive daily active stimulation (2 mA) to the left dorsolateral prefrontal cortex for 4 weeks through a home-based tDCS device in remotely-supervised 30-min sessions.
  • Sham Comparator: Sham tDCS
    This group will receive daily sham stimulation to the left dorsolateral prefrontal cortex for 4 weeks through a home-based tDCS device in remotely-supervised 30-min sessions.

Primary Outcome Measure

Inhibitory Control [ Time Frame: Baseline ]

Locations (1)

FacilityCityStateZIP
Massachusetts General HospitalCharlestownMassachusetts02129

Find similar trials in Charlestown, MA

By condition
COVID-19 / long COVID
By specialty
Infectious disease
By research site
Massachusetts General Hospital· Charlestown, MA

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