A Clinical Study to Explore the Efficacy and Safety of Tislelizumab in Combination With Bevacizumab and Chemotherapy in Patients With Persistent, Recurrent, or Metastatic Cervical Cancer
- Sponsor
- Zhejiang Cancer Hospital
- Study ID
- NCT05247619
- Phase
- PHASE2
- Status
- Unknown
Conditions
Eligibility Criteria
- Sex
- FEMALE
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Tislelizumab / Bevacizumab/Paclitaxel/Cisplatin/Carboplatin — DRUGTisleliumab 200mg, Bevacizumab 7.5mg/kg, Paclitaxel 175mg/m2, and Cisplatin 50mg/m2 (or Carboplatin AUC5) IV on day 1 of every 21-day cycle.
Study Details
Efficacy and safety of Tislelizumab combined with Bevacizumab and chemotherapy in patients with persistent, recurrent or metastatic cervical cancer.
Key Dates
- First listed
- Feb 21, 2022
- Start date
- Jun 30, 2022
- Status verified
- Jul 2022
- Primary completion
- Aug 31, 2024
- Completion
- Jan 31, 2025
Study Design
- Enrollment
- 49 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: InterventionTislelizumab + Bevacizumab + Paclitaxel + Cisplatin/Carboplatin
Primary Outcome Measure
mPFS [ Time Frame: The time from the first dosing of the study drug until the first objective recording of disease progression or death from any cause, whichever occurred first, up to approximately 24 months. ]
Central Contacts
- jianqing zhu, docter13605818467
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