A New Prognostic Stratification-based Safety and Efficacy Study of Ruxolitinib in Myelofibrosis
- Sponsor
- Qilu Hospital of Shandong University
- Study ID
- NCT05447260
- Phase
- PHASE4
- Status
- Unknown
Conditions
- Myelofibrosis
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Ruxolitinib — DRUGDosage based on platelet count
Study Details
This is a multi-center, prospective, single-arm study to assess safety and efficacy of Ruxolitinib in myelofibrosis (MF) based on a new prognostic stratification.
Key Dates
- Start date
- Jun 10, 2022
- Status verified
- Jul 2022
- Primary completion
- Dec 10, 2022
- Completion
- Dec 10, 2023
Study Design
- Enrollment
- 87 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Ruxolitinib
Primary Outcome Measure
The proportion of patients with a ≥35% reduction in palpable spleen volume from baseline. [ Time Frame: From Week 0 through Week 24 ]
Central Contacts
- Chen18560087023
- Yu
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