Familial B-cell Lymphoproliferative Disorders
- Sponsor
- University of Haifa
- Study ID
- NCT05718986
- Status
- Not Yet Recruiting
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Conditions
- Chronic Lymphocytic Leukemia
- Lymphoproliferative Disorders
- Monoclonal B-Cell Lymphocytosis
- Premalignant
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Accepted
Interventions
- No intervention — OTHERNo intervention
Study Details
This study investigates families with at least two cases of B-cell lymphoproliferative disorders (LPD), and evaluates the prevalence of LPD in families, the relationship between medical history, genetic factors, and the risk of familial LPD, and various clinical outcomes for these families in a multiethnic population of Jews and Arabs in Israel.
Key Dates
- First listed
- Feb 8, 2023
- Start date
- Jun 30, 2024
- Status verified
- May 2024
- Primary completion
- Dec 31, 2028
- Completion
- Dec 31, 2040
Study Design
- Enrollment
- 1,000 participants (estimated)
Arms
- Arm: Bnai Zion Medical CenterBnai Zion Medical Center
- Arm: Tel Aviv Sourasky Medical Center - Ichilov HospitalTel Aviv Sourasky Medical Center - Ichilov Hospital
- Arm: Galil Medical CenterGalil Medical Center
- Arm: Ziv Medical CenterZiv Medical Center
- Arm: Emek Medical CenterEmek Medical Center
- Arm: Beilinson HospitalBeilinson Hospital
- Arm: Meir Medical CenterMeir Medical Center
- Arm: Kaplan Medical CenterKaplan Medical Center
- Arm: Sheba Medical CenterSheba Medical Center
- Arm: Rambam Medical CenterRambam Medical Center
- Arm: Shaare Zdek Medical CenterShaare Zdek Medical Center
- Arm: Hadassah Medical CenterHadassah Medical Center
- Arm: Shamir Medical Center (Assaf Harofeh)Shamir Medical Center (Assaf Harofeh)
- Arm: Soroka Medical CenterSoroka Medical Center
- Arm: Assuta Ashdod HospitalAssuta Ashdod Hospital
Primary Outcome Measure
Prevalence of familial LPD in Israel [ Time Frame: 5 years ]
Central Contacts
- Geffen Kleinstern, PhD+972545715624
- Tamar Tadmor, MD
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