A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis

Sponsor
Qianfoshan Hospital
Study ID
NCT05895409
Status
Recruiting
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Conditions

  • Interstitial Lung Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to learn about risk of progressive pulmonary fibrosis (PPF). The main questions it aims to answer are: * Risk factors of PPF * Prevalence of PPF * Mortality of PPF Patients with interstitial lung disease (ILD) of known or unknown etiology other than IPF who has radiological evidence of pulmonary fibrosis will enroll in this study. * All participants will have baseline investigations at the first visit having provided informed consent. * At the first visit, baseline characteristics will be collected including demographics, medical history, smoking history, complications and medication use. 50 mL of blood will be obtained. High resolution computed tomography (HRCT), full lung function tests and a 6 min walk test will be performed. * Further visits at 6 months and 12 months will include further 50 mL blood sampling. HRCT, full lung function tests and a 6 min walk test will be repeated.

Key Dates

First listed
Jun 8, 2023
Start date
Jul 27, 2023
Status verified
Nov 2023
Primary completion
Jun 1, 2026
Completion
Jun 1, 2028

Study Design

Enrollment
610 participants (estimated)

Arms

  • Arm: PF
    Patients with interstitial lung disease (ILD) of known or unknown etiology other than IPF who has radiological evidence of pulmonary fibrosis(PF).

Primary Outcome Measure

Establish the correlation between Age (years) and progression to PPF [ Time Frame: Up to 12 months ]

Central Contacts

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