The Efficacy and Safety of TAS-102(Suyuan) Combined With Bevacizumab as First-line Therapy in Patients With Advanced Colorectal Cancer
- Sponsor
- The Second Affiliated Hospital of Shandong First Medical University
- Study ID
- NCT06092242
- Phase
- PHASE2
- Status
- Not Yet Recruiting
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Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 85 Years
- Healthy Volunteers
- Not accepted
Interventions
- Tas-102(Suyuan) combined with bevacizumab — DRUGTas-102: po 35 mg/m2, bid, d1-5, d8-12, Q4 wks; bevacizumab: intravenous drip 5 mg/kg, D1, D15, Q4 wks.
Study Details
To evaluate the efficacy and safety of TAS-102 combined with bevacizumab as first-line therapy in patients with advanced colorectal cancer who could not tolerate or did not receive combined chemotherapy
Key Dates
- First listed
- Oct 23, 2023
- Start date
- Oct 15, 2023
- Status verified
- Oct 2023
- Primary completion
- Oct 15, 2025
- Completion
- Oct 15, 2027
Study Design
- Enrollment
- 50 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: TAS-102 combined with bevacizumab
Primary Outcome Measure
Progression Free Survival [ Time Frame: 2 years ]
Central Contacts
- Ying Kong13153882807
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