Non-invasive Evaluation of Graft Condition in Adult Patients With Kidney Transplant Using Ultrasound Localization Microscopy and Multispectral Optoacoustic Tomography

Sponsor
University of Erlangen-Nürnberg Medical School
Study ID
NCT06472947
Status
Recruiting
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Conditions

  • Kidney Biopsy
  • Kidney Transplant

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • ULM and MSOT — DEVICE
    transplanted kidney will be examined non-invasively with ULM and MSOT

Study Details

In this study, the condition of the kidney transplant in adults is to be assessed non-invasively using Multispectral Optoacoustic Tomography and Ultrasound Localization Microscopy (ULM). ULM imaging can be performed in a 2-dimensional and a 3-dimensional way (2D and 3D ULM). Therefore, "ULM" in the following texts and measures will refer to 2D and 3D ULM. New, non-invasive markers that allow conclusions to be drawn about the condition of the transplant should reduce the need for invasive diagnostic procedures in the future.

Key Dates

First listed
Jun 25, 2024
Start date
Jun 18, 2024
Status verified
Mar 2026
Primary completion
Jan 18, 2028
Completion
Jan 18, 2028

Study Design

Enrollment
10 participants (estimated)

Arms

  • Arm: Patient with kidney transplant
    Included are adult (\> 18 years) patients with kidney transplant where the indication for a kidney biopsy has been set during clinical routine

Primary Outcome Measure

Visualization of microvascular architecture in the transplant kidney [ Time Frame: Day1 ]

Central Contacts

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