Urinary Neurotrophin Levels as Potential Biomarkers for Overactive Bladder: A Case-Control Study

Sponsor
Erzincan Binali Yildirim Universitesi
Study ID
NCT06563193
Status
Enrolling By Invitation

Conditions

  • Overactive Bladder

Eligibility Criteria

Sex
ALL
Age
18 Years - 50 Years
Healthy Volunteers
Accepted

Interventions

  • NERVE GROWTH FACTOR — DIAGNOSTIC_TEST
    urinary neurotrophins

Study Details

Overactive bladder is a prevalent urological disorder marked by symptoms such as urinary urgency, increased frequency of urination, and nighttime urination (nocturia). Neurotrophins, including nerve growth factor and brain-derived neurotrophic factor, play crucial roles in the development and function of neurons. Recent research has suggested a possible connection between these neurotrophins and OAB. This study sought to explore the relationship between urinary levels of NGF and BDNF and the presence of OAB.

Key Dates

First listed
Aug 20, 2024
Start date
Aug 15, 2024
Status verified
Aug 2024
Primary completion
May 1, 2025
Completion
Jun 1, 2025

Study Design

Enrollment
44 participants (estimated)

Arms

  • Arm: overactive bladder group
    OAB was diagnosed according to the patient's complaint of urgency with or without urge incontinence as the core symptom according to the criteria defined by the International Continence Society
  • Arm: control group
    As a control group, patients who were admitted to the outpatient clinic for other reasons and who did not have OAB symptoms and have normal voiding functions were included

Primary Outcome Measure

NGF anf BDNF levels in overactive bladder patients [ Time Frame: 6 months ]

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