A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer
- Sponsor
- Feng Wang
- Study ID
- NCT06682247
- Status
- Not Yet Recruiting
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Conditions
- Colorectal Cancer Metastatic
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Chidamide, Tucidinostat; PD-1/PD-L1 inhibitor or double antibodies; Bevacizumab or tyrosine kinase inhibitors — DRUGChidamide, Tucidinostat; PD-1/PD-L1 inhibitor or double antibodies; Bevacizumab or tyrosine kinase inhibitors
Study Details
This is an observational , multicenter, real-world study aimed at evaluating the efficacy and safety of the combination of immune checkpoint inhibitors, chidamide and antiangiogenic agents in Microsatellite Stable advanced colorectal cancer patients.
Key Dates
- First listed
- Nov 12, 2024
- Start date
- Nov 15, 2024
- Status verified
- Nov 2024
- Primary completion
- Jun 15, 2025
- Completion
- Dec 31, 2025
Study Design
- Enrollment
- 200 participants (estimated)
Arms
- Arm: chidamide + PD-1/PD-L1 inhibitors +Bevacizumab or tyrosine kinase inhibitors
Primary Outcome Measure
Progression-free survival(PFS) [ Time Frame: 2 years ]
Central Contacts
- feng wang020-87343088
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