Prospective Observational Cohort Study on Impact of Frailty on Risk Prediction, Treatment Strategies, and Short-Term Outcomes in Patients With Acute Coronary Syndrome
- Sponsor
- Assiut University
- Study ID
- NCT07190274
- Status
- Not Yet Recruiting
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Conditions
- ACS (Acute Coronary Syndrome)
- Frailty
- GRACE Score
- MACE
Eligibility Criteria
- Sex
- ALL
- Age
- 65 Years - N/A
- Healthy Volunteers
- Not accepted
Study Details
we aim : * To evaluate how frailty influences acute management decisions (invasive vs conservative strategy) in ACS patients and whether it independently affects short-term outcomes. * To determine whether adding frailty assessment to existing ACS risk prediction models improves the prediction of 30-day mortality and major adverse cardiovascular events (MACE) in elderly ACS patients.
Key Dates
- First listed
- Sep 24, 2025
- Start date
- Dec 1, 2025
- Status verified
- Sep 2025
- Primary completion
- Dec 1, 2027
- Completion
- Jun 1, 2028
Study Design
- Enrollment
- 645 participants (estimated)
Primary Outcome Measure
30-day Major Adverse Cardiovascular Events (MACE) [ Time Frame: 30 days after index admission ]
Central Contacts
- Fady Gamal Habib+201004721578
- Ahmed Abdelgaleel+201005015156
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