Eye Movement Parameters and Cognitive Functions in Older Adults

Sponsor
National Sun Yat-sen University
Study ID
NCT07358598
Status
Not Yet Recruiting

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Conditions

  • Cognitive Dysfunction

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Accepted

Study Details

Dementia most commonly occurs in elderly individuals, but currently there is still a lack of objective measurement methods that can detect cognitive impairment in older adults at an early stage. Eye movement is considered a clinical indicator with potential for screening mild cognitive dysfunction, and eye movement signals can be extracted to objectively evaluate cognition. Eye tracking has been used mostly to evaluate patients with neurodegenerative diseases such as Parkinson's disease. However, less attention has been paid to the relationship between eye movement and cognitive function in elderly individuals, as well as the association between eye movement data and abnormal cognitive subdomains. This cross-sectional study will recruit 0204 elderly individuals over the age of 65, divided into three groups (healthy group/mild cognitive impairment group/dementia group) according to the purpose of this study. Participants who have not been diagnosed with neurological diseases (such as Parkinson's disease or stroke), or have mental illness or visual impairments will be excluded. This study hopes to provide empirical data on eye movement signals and cognitive function in healthy older individuals, as well as to serve as a preliminary study for future development of eye activity stimulation to improve cognitive function in older adults.

Key Dates

First listed
Jan 22, 2026
Start date
Jan 17, 2026
Status verified
Jan 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
210 participants (estimated)

Arms

  • Arm: Healthy group-patients with intact cognitive function
  • Arm: Mild cognitive impairment group-patients with mild cognitive impairment
  • Arm: Dementia group-patients with severe cognitive impairment

Primary Outcome Measure

Eye-tracking measurement [ Time Frame: A single assessment is conducted at one study visit (cross-sectional design). ]

Central Contacts

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