Hyperbaric Oxygen Therapy in Complex Regional Pain Syndrome

Sponsor
University Hospital Ostrava
Study ID
NCT07446712
Status
Not Yet Recruiting

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Conditions

  • Chronic Pain
  • Complex Regional Pain Syndrome

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Early hyperbaric oxygen therapy (HBOT) — PROCEDURE
    The hyperbaric oxygen therapy (HBOT) will be initiated immediately after enrolment
  • Delayed hyperbaric oxygen therapy (HBOT) — PROCEDURE
    The hyperbaric oxygen therapy (HBOT) will be initiated 4-6 weeks after enrolment.

Study Details

The aim of the study is to investigate the efficacy of hyperbaric oxygen therapy as an adjunct in the management of severe complex regional pain syndrome.

Key Dates

First listed
Mar 3, 2026
Start date
Apr 30, 2026
Status verified
Feb 2026
Primary completion
Apr 30, 2028
Completion
Apr 30, 2029

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Early group
    Participants in the EARLY group will undergo HBOT immediately after baseline assessment (T0).
  • Experimental: Delayed group
    Participants in the DELAYED group will receive usual care until T1 (4-6 weeks), after which they will cross over to receive the same HBOT regimen.

Primary Outcome Measure

Clinical functional test - active wrist range of motion [ Time Frame: The early group will receive 20-30 HBOT sessions over 4-6 week period and will be evaluated (T1) at baseline. The same evaluation T1 will be made for the second (delayed) group 4-6 weeks after baseline evaluation T0. ]

Central Contacts

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