A Comparison of the Efficacy of Different Rehabilitation Strategies in Mild Cognitive Impairment

Sponsor
Istanbul University - Cerrahpasa
Study ID
NCT07547111
Status
Not Yet Recruiting

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Conditions

  • Mild Cognitive Impairment (MCI)

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Dual Task Training — OTHER
    Week Motor Task Cognitive Task Week 1 Straight walking Counting numbers Week 2 Straight walking Naming fruit images Week 3 Balancing Counting backward (feet together, tandem) Week 4 Throwing a ball Word generation (words starting with 'A') Week 5 Catching a ball Counting by 2s and 4s Week 6 Zigzag walking Reciting days of the week backward Week 7 Walking with obstacles Responding to non-animal words Week 8 Changing direction Verbal commands (e.g., "turn right if yellow, turn left if blue, or vice versa")
  • The computer-assisted cognitive rehabilitation — OTHER
    The computer-assisted cognitive rehabilitation intervention will be conducted via the RehaCom (Hasomed, Germany) platform. The intervention program is designed to include combinations of modules targeting selective and divided attention, executive functions, processing speed, and visuospatial perception, with each session lasting 40 minutes. It will be implemented in a stepwise manner, with content and difficulty levels gradually increasing every two weeks.

Study Details

The aim of this study is to conduct a comparative analysis of the effects of two different rehabilitation approaches on cognitive and functional outcomes in older adults diagnosed with mild cognitive impairment (MCI). The study compares two widely used approaches in the field of cognitive rehabilitation: Computer-Based Cognitive Rehabilitation (CBCR) and Dual-Task Training (DTT). The planned study will be conducted using a randomized controlled, parallel-group experimental design, in which individuals aged 65 and older diagnosed with MCI will be assigned to two intervention groups via computer-assisted randomization. Both groups will receive training for eight weeks, twice a week for 45 minutes each session, under the supervision of a specialist physical therapist. Pre- and post-intervention assessments will measure general cognitive function, executive function, fall risk, dual-task performance, functional independence, fear of falling, and physical activity level. This study is based on the assumption that cognitive decline is not limited to neuropsychological performance alone but is closely related to motor performance, safe mobility, and quality of life. The findings are expected to contribute to clinical decision-making processes by providing evidence-based data on which rehabilitation approach is more effective and feasible for older adults with HBB.

Key Dates

First listed
Apr 23, 2026
Start date
Apr 17, 2026
Status verified
Apr 2026
Primary completion
Apr 1, 2027
Completion
Dec 1, 2027

Study Design

Enrollment
42 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Dual Task Group
    Dual-task training will be implemented in parallel with the cognitive rehabilitation intervention and will be structured to target cognitive domains such as selective and divided attention, executive functions, processing speed, and visuospatial perception. The intervention will last a total of eight weeks, with content and difficulty levels progressing every two weeks. The program will begin with a low cognitive load and will be gradually increased in difficulty based on the individual's performance.
  • Active Comparator: Computer-Assisted Cognitive Rehabilitation Group
    The computer-assisted cognitive rehabilitation intervention will be conducted via the RehaCom (Hasomed, Germany) platform. The intervention program is designed to include combinations of modules targeting selective and divided attention, executive functions, processing speed, and visuospatial perception, with each session lasting 40 minutes. It will be implemented in a stepwise manner, with content and difficulty levels gradually increasing every two weeks.

Primary Outcome Measure

Mini Mental State Examination [ Time Frame: baseline and at the end of the 8-week intervention ]

Central Contacts

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