Comparison of Intraperitoneal Bupivacaine and Saline Irrigation for Pain Relief After Laparoscopic Cholecystectomy

Sponsor
Wah Medical college , POF hospital
Study ID
NCT07650760
Phase
PHASE4
Status
Recruiting
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Conditions

  • Postoperative Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • Bupivacain — DRUG
    In group A intraperitoneal bupivacaine is used for pain relief
  • Saline (0.9% NaCl) — DRUG
    In group B intraperitoneal saline is used for pain relief as placebo.

Study Details

This randomized clinical trial compared intraperitoneal irrigation of bupivacaine(a local anesthetic) vs a control group receiving normal saline for relief of post operative pain following laparoscopic gallbladder surgery. A total of 106 patients divided into two equal groups, with one group receiving bupivacaine and the other treated using normal saline(control).Previous studies on the subject found that bupivacaine significantly reduced postoperative pain. Although conventional intravenous analgesics remain widely used, bupivacaine may be a better option, especially in difficult surgical cases.

Key Dates

First listed
Jun 16, 2026
Start date
Jul 1, 2026
Status verified
Jun 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
106 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Experimental : group A: bupivacaine
    Group A is the arm where patients have received intraperitoneal bupivacaine during laparoscopic gallbladder surgery, and their post operative pain is compared .
  • Placebo Comparator: Placebo : group B: saline
    Placebo : group B: saline Group B is the arm where patients have received only intraperitoneal normal saline .

Primary Outcome Measure

Post operative pain relief [ Time Frame: From the completion of the procedure til one hour after surgery ]

Central Contacts

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