A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health

Part of paid clinical trials in Fort Wayne, Indiana.

Sponsor
HALEON
Study ID
NCT07704905
Status
Recruiting
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Conditions

  • Dental Plaque
  • Gingivitis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Test Dentifrice — DRUG
    Experimental dentifrice containing 0.454% w/w SnF2.
  • Reference Dentifrice (Colgate Cavity Protection Dentifrice) — DRUG
    A marketed regular fluoride dentifrice.

Study Details

The aim of this study will be to evaluate the ability of using an experimental dentifrice containing 0.454 percent (%) weight for weight (w/w) Stannous Fluoride (SnF2) to reduce gingivitis and plaque accumulation, compared with a regular fluoride toothpaste (negative control) in participants with mild to moderate gingivitis.

Key Dates

First listed
Jul 15, 2026
Start date
Jul 13, 2026
Status verified
Aug 2026
Primary completion
Oct 31, 2026
Completion
Oct 31, 2026

Study Design

Enrollment
110 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Test Dentifrice
    Participants will brush their teeth thoroughly for at least one timed minute twice daily (morning and evening) for 8 Weeks, using a full ribbon of Test Dentifrice on the head of the toothbrush provided.
  • Active Comparator: Reference Dentifrice
    Participants will brush their teeth thoroughly for at least one timed minute twice daily (morning and evening) for 8 Weeks, using a full ribbon of Reference Dentifrice on the head of the toothbrush provided.

Primary Outcome Measure

Change from Baseline in Overall Modified Gingival Index (MGI) at Week 8 [ Time Frame: Baseline and Week 8 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Salus Research IncFort WayneIndiana46825
Jeffery L Milleman, DDS
[email protected]

Find similar trials in Fort Wayne, IN

By research site
Salus Research Inc· Fort Wayne, IN

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