CPB and Aortic Cross-Clamp Durations and ICU Length of Stay After CABG Retrospective Observational Cohort Study

Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Study ID
NCT07711951
Status
Recruiting
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Conditions

  • Coronary Artery Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Cardiopulmonary Bypass Duration — OTHER
    Cardiopulmonary bypass duration, defined as the total duration of cardiopulmonary bypass during elective isolated coronary artery bypass graft surgery and recorded in minutes. This exposure will be evaluated as a continuous variable based on routinely collected perfusion records.
  • Aortic Cross-Clamp Duration — OTHER
    Aortic cross-clamp duration, defined as the total duration of aortic cross-clamping during elective isolated coronary artery bypass graft surgery and recorded in minutes. This exposure will be evaluated as a continuous variable based on routinely collected operative and perfusion records.

Study Details

Cardiopulmonary bypass (CPB) and aortic cross-clamp (ACC) durations are important intraoperative factors that may influence postoperative recovery following coronary artery bypass graft (CABG) surgery. Prolonged CPB and ACC durations may be associated with increased postoperative morbidity and extended intensive care unit (ICU) stay. This retrospective observational cohort study aims to evaluate the independent associations of CPB and ACC durations with postoperative ICU length of stay in adult patients undergoing elective isolated CABG surgery. Electronic medical records of eligible patients who underwent surgery between January 1, 2019, and December 31, 2025, at a single tertiary care center will be retrospectively reviewed. Multivariable regression analyses will be performed to assess these associations after adjustment for clinically relevant potential confounders.

Key Dates

First listed
Jul 17, 2026
Start date
Jul 20, 2026
Status verified
Jul 2026
Primary completion
Aug 30, 2026
Completion
Aug 30, 2026

Study Design

Enrollment
400 participants (estimated)

Arms

  • Arm: Elective Isolated CABG Cohort
    Adult patients who underwent elective isolated coronary artery bypass graft surgery between January 1, 2019, and December 31, 2025, and met the predefined eligibility criteria. Cardiopulmonary bypass and aortic cross-clamp durations will be evaluated as continuous exposure variables.

Primary Outcome Measure

Postoperative Intensive Care Unit Length of Stay [ Time Frame: Up to 30 days after surgery ]

Central Contacts

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