AMG 436 Clinical Trials (2026): 1 Studies for Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
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1 AMG 436 clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 1 indication (including Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)) and 464 total planned enrollment. 1 AMG 436 clinical trial is actively recruiting at 5 U.S. sites across 5 states. Most recent activity: NCT07403721 (Jun 2028).
Where to Participate: All AMG 436 Trial Sites in the U.S. (5 sites across 5 states)
Every actively recruiting AMG 436trial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| CA | City of Hope Orange County Lennar Foundation Cancer Center | Irvine92618 | NCT07403721 | Map |
| IL | Midwestern Regional Medical Center dba City of Hope Chicago | Zion60099 | NCT07403721 | Map |
| ME | New England Cancer Specialists | Westbrook04092 | NCT07403721 | Map |
| TN | Tennessee Oncology PLLC | Nashville37203 | NCT07403721 | Map |
| TX | Next Oncology - Dallas | Irving75039 | NCT07403721 | Map |
AMG 436 clinical trials at a glance: phase × recruitment status
| Phase | recruiting | Total |
|---|---|---|
| P1 | 1 | 1 |
Recruiting AMG 436 clinical trials (1)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT07403721 | AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors | P1 | Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR) | 464 | Apr 2026 |
All AMG 436 trials (1)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT07403721 | AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors | P1 | recruiting | 464 | Amgen | Apr 2026 |
AMG 436 clinical trials: frequently asked questions
- How many AMG 436 clinical trials are there?
- 1 AMG 436 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants.
- Are AMG 436 clinical trials recruiting in 2026?
- Yes — 1 AMG 436 trial is actively recruiting in 2026, with 5 U.S. sites across 5 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is AMG 436 being studied for?
- AMG 436 is being studied for Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR). The trials are grouped by indication on this page.
- What phase is AMG 436 in?
- AMG 436 clinical trials span 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors AMG 436 clinical trials?
- The lead sponsor across the most AMG 436 trials is Amgen. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming AMG 436as an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
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