Iadademstat Clinical Trials (2026): 8 Studies for Acute Myeloid Leukemia & Acute Myeloid Leukemia Refractory

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

8 Iadademstat clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 7 indications (including Acute Myeloid Leukemia & Acute Myeloid Leukemia Refractory) and 295 total planned enrollment. 5 Iadademstat clinical trials are actively recruiting at 74 U.S. sites across 21 states. Most recent activity: NCT07113691 (Jan 2030).

Where to Participate: All Iadademstat Trial Sites in the U.S. (74 sites across 21 states)

Every actively recruiting Iadademstattrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
CACity of Hope Comprehensive Cancer CenterDuarte91010NCT06287775Map
CACity of Hope at Irvine LennarIrvine92618NCT06287775Map
CAUCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine92612NCT06661915Map
CAUC San Diego Moores Cancer CenterLa Jolla92093NCT06287775Map
CAUC Irvine Health/Chao Family Comprehensive Cancer CenterOrange92868NCT06661915Map
CAStanford Cancer Institute Palo AltoPalo Alto94304NCT06661915Map
CAUniversity of California Davis Comprehensive Cancer CenterSacramento95817NCT06661915Map
CAUniversity of California Davis Comprehensive Cancer CenterSacramento95817NCT06287775Map
CTYale UniversityNew Haven06520NCT06287775Map
CTYale UniversityNew Haven06510NCT07113691Map
CTYale-New Haven Hospital North Haven Medical CenterNorth Haven06473NCT06287775Map
CTSmilow Cancer Hospital Care Center-TrumbullTrumbull06611NCT06287775Map
DCMedStar Georgetown University HospitalWashington D.C.20007NCT06287775Map
FLUM Sylvester Comprehensive Cancer Center at Coral GablesCoral Gables33146NCT06661915Map
FLUM Sylvester Comprehensive Cancer Center at Coral SpringsCoral Springs33065NCT06661915Map
FLUM Sylvester Comprehensive Cancer Center at Deerfield BeachDeerfield Beach33442NCT06661915Map
FLUM Sylvester Comprehensive Cancer Center at DoralDoral33166NCT06661915Map
FLUF Health Cancer Institute - GainesvilleGainesville32610NCT06287775Map
FLUM Sylvester Comprehensive Cancer Center at HollywoodHollywood33021NCT06661915Map
FLUM Sylvester Comprehensive Cancer Center at KendallMiami33176NCT06661915Map
FLUniversity of Miami Miller School of Medicine-Sylvester Cancer CenterMiami33136NCT06661915Map
FLUniversity of Miami Sylvester Comprehensive Cancer Center at Sole MiaNorth Miami33181NCT06661915Map
FLUM Sylvester Comprehensive Cancer Center at PlantationPlantation33324NCT06661915Map
FLMoffitt Cancer CenterTampa33612NCT06661915Map
GAEmory Saint Joseph's HospitalAtlanta30342NCT06287775Map
GAEmory University Hospital MidtownAtlanta30308NCT06287775Map
GAEmory University Hospital/Winship Cancer InstituteAtlanta30322NCT06287775Map
ILUniversity of Chicago Comprehensive Cancer CenterChicago60637NCT06661915Map
ILUniversity of Chicago Comprehensive Cancer CenterChicago60637NCT06287775Map
ILUC Comprehensive Cancer Center at Silver CrossNew Lenox60451NCT06661915Map
ILUC Comprehensive Cancer Center at Silver CrossNew Lenox60451NCT06287775Map
ILUniversity of Chicago Medicine-Orland ParkOrland Park60462NCT06661915Map
ILUniversity of Chicago Medicine-Orland ParkOrland Park60462NCT06287775Map
INUChicago Medicine Northwest IndianaCrown Point46307NCT06661915Map
INUChicago Medicine Northwest IndianaCrown Point46307NCT06287775Map
KSUniversity of Kansas Clinical Research CenterFairway66205NCT06661915Map
KSUniversity of Kansas Clinical Research CenterFairway66205NCT06287775Map
KSUniversity of Kansas Cancer CenterKansas City66160NCT06661915Map
KSUniversity of Kansas Cancer CenterKansas City66160NCT06287775Map
KSUniversity of Kansas Hospital-Indian Creek CampusOverland Park66211NCT06661915Map
KSUniversity of Kansas Hospital-Indian Creek CampusOverland Park66211NCT06287775Map
KSUniversity of Kansas Hospital-Westwood Cancer CenterWestwood66205NCT06661915Map
KSUniversity of Kansas Hospital-Westwood Cancer CenterWestwood66205NCT06287775Map
KYUniversity of Kentucky/Markey Cancer CenterLexington40536NCT06287775Map
MDJohns Hopkins University/Sidney Kimmel Cancer CenterBaltimore21287NCT06287775Map
MDUniversity of Maryland/Greenebaum Cancer CenterBaltimore21201NCT06287775Map
NJMemorial Sloan Kettering Basking RidgeBasking Ridge07920NCT06287775Map
NJMemorial Sloan Kettering MonmouthMiddletown07748NCT06287775Map
NJMemorial Sloan Kettering BergenMontvale07645NCT06287775Map
NYMemorial Sloan Kettering CommackCommack11725NCT06287775Map
NYMemorial Sloan Kettering WestchesterHarrison10604NCT06287775Map
NYMemorial Sloan Kettering Cancer CenterNew York10065NCT06287775Map
NYNYP/Weill Cornell Medical CenterNew York10065NCT06661915Map
NYMemorial Sloan Kettering NassauUniondale11553NCT06287775Map
NCCarolinas Medical Center/Levine Cancer InstituteCharlotte28203NCT06661915Map
NCCarolinas Medical Center/Levine Cancer InstituteCharlotte28203NCT06287775Map
NCAtrium Health Cabarrus/LCI-ConcordConcord28025NCT06661915Map
NCAtrium Health Cabarrus/LCI-ConcordConcord28025NCT06287775Map
NCWake Forest University Health SciencesWinston-Salem27157NCT06287775Map
OHUniversity of Cincinnati Cancer Center-UC Medical CenterCincinnati45219NCT06287775Map
OHCase Western Reserve UniversityCleveland44106NCT06287775Map
OHOhio State University Comprehensive Cancer CenterColumbus43210NCT06661915Map
OHOhio State University Comprehensive Cancer CenterColumbus43210NCT06287775Map
OHUniversity of Cincinnati Cancer Center-West ChesterWest Chester45069NCT06287775Map
OKUniversity of Oklahoma Health Sciences CenterOklahoma City73104NCT06661915Map
OROHSU Knight Cancer InstitutePortland97239NCT06357182Map
OROregon Health and Science UniversityPortland97239NCT06661915Map
PAUPMC Hillman Cancer CenterPittsburgh15232NCT06287775Map
TNVanderbilt University/Ingram Cancer CenterNashville37232NCT06661915Map
UTHuntsman Cancer Institute/University of UtahSalt Lake City84112NCT06661915Map
VAUniversity of Virginia Cancer CenterCharlottesville22908NCT06287775Map
VAVCU Massey Comprehensive Cancer CenterRichmond23298NCT06661915Map
VAVCU Massey Comprehensive Cancer CenterRichmond23298NCT06287775Map
WIFroedtert Hospital & the Medical College of WisconsinMilwaukee53226NCT06502145Map

Iadademstat clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingterminatedsuspendedTotal
P13115
P1/P211
P2112

Recruiting Iadademstat clinical trials (5)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT07113691TIARAIadademstat + SBRT With Atezo in ES-SCLCP1Extensive Stage Small Cell Lung Cancer (ES-SCLC)15Jan 2026
NCT06287775Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung CancerP1/P2Extensive Stage Lung Small Cell Carcinoma45Apr 2025
NCT06357182Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid LeukemiaP1Acute Myeloid Leukemia30Aug 2024
NCT06661915A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)P2Accelerated Phase Myeloproliferative Neoplasm78Aug 2025
NCT06502145Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic SyndromeP1Myelodysplastic Syndromes12Jan 2025

Iadademstat clinical trials by indication

Acute Myeloid Leukemia (2)

NCTAcronymPhaseStatusTitle
NCT06357182P1recruitingIadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia
NCT06514261P1suspendedTesting the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML

Extensive Stage Small Cell Lung Cancer (ES-SCLC) (1)

NCTAcronymPhaseStatusTitle
NCT07113691TIARAP1recruitingIadademstat + SBRT With Atezo in ES-SCLC

Accelerated Phase Myeloproliferative Neoplasm (1)

NCTAcronymPhaseStatusTitle
NCT06661915P2recruitingA Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

Extensive Stage Lung Small Cell Carcinoma (1)

NCTAcronymPhaseStatusTitle
NCT06287775P1/P2recruitingTesting the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Myelodysplastic Syndromes (1)

NCTAcronymPhaseStatusTitle
NCT06502145P1recruitingIadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome

Small-cell Lung Cancer (1)

NCTAcronymPhaseStatusTitle
NCT05420636P2terminatedIadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET

Acute Myeloid Leukemia, in Relapse (1)

NCTAcronymPhaseStatusTitle
NCT05546580FRIDAP1active not recruitingStudy of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)

Terminated and withdrawn Iadademstat trials (2)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

  • NCT06514261suspendedTesting the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML
  • NCT05420636terminatedIadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NET

All Iadademstat trials (8)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT07113691TIARAIadademstat + SBRT With Atezo in ES-SCLCP1recruiting15Yale UniversityJan 2026
NCT06287775Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung CancerP1/P2recruiting45National Cancer Institute (NCI)Apr 2025
NCT06357182Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid LeukemiaP1recruiting30OHSU Knight Cancer InstituteAug 2024
NCT06661915A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)P2recruiting78National Cancer Institute (NCI)Aug 2025
NCT06502145Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic SyndromeP1recruiting12Medical College of WisconsinJan 2025
NCT06514261Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AMLP1suspended45National Cancer Institute (NCI)Dec 2024
NCT05546580FRIDAStudy of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)P1active not recruiting50Oryzon Genomics S.A.Nov 2022
NCT05420636Iadademstat in Combination With Paclitaxel in Relapsed/Refractory SCLC and Extrapulmonary High Grade NETP2terminated20Fox Chase Cancer CenterDec 2022

Iadademstat clinical trials: frequently asked questions

How many Iadademstat clinical trials are there?
8 Iadademstat clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 5 are actively recruiting participants.
Are Iadademstat clinical trials recruiting in 2026?
Yes — 5 Iadademstat trials are actively recruiting in 2026, with 74 U.S. sites across 21 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Iadademstat being studied for?
Iadademstat is being studied for Acute Myeloid Leukemia, Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in Relapse, Blast Phase Myeloproliferative Neoplasm, Essential Thrombocythemia and 13 more. The trials are grouped by indication on this page.
What phase is Iadademstat in?
Iadademstat clinical trials span 2 Phase 2, 5 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Iadademstat clinical trials?
The lead sponsor across the most Iadademstat trials is National Cancer Institute (NCI), with 5 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Iadademstatas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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