How many Sonrotoclax clinical trials are there?

24 Sonrotoclax clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 14 are actively recruiting participants. 2 are marked completed.

Are Sonrotoclax clinical trials recruiting in 2026?

Yes — 14 Sonrotoclax trials are actively recruiting in 2026, with 270 U.S. sites across 38 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Sonrotoclax being studied for?

Sonrotoclax is being studied for Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Small Lymphocytic Lymphoma, Acute Myeloid Leukemia, Refractory Mantle Cell Lymphoma and 43 more. The trials are grouped by indication on this page.

What phase is Sonrotoclax in?

Sonrotoclax clinical trials span 5 Phase 3, 11 Phase 2, 5 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Sonrotoclax clinical trials?

The lead sponsor across the most Sonrotoclax trials is BeOne Medicines, with 12 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sonrotoclax Clinical Trials (2026): 24 Studies for Chronic Lymphocytic Leukemia & Mantle Cell Lymphoma

Creator: Hipa.ai Research
Published: 2026-05-26T17:51:15.330Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: July 17, 2026.

24 Sonrotoclax clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 14 indications (including Chronic Lymphocytic Leukemia & Mantle Cell Lymphoma) and 4,506 total planned enrollment. 5 Phase 3 Sonrotoclax trials and 11 Phase 2 are listed. 17 Sonrotoclax clinical trials are actively recruiting at 270 U.S. sites across 38 states. Most recent activity: NCT06854003 (Nov 2039).

Where to Participate: All Sonrotoclax Trial Sites in the U.S. (270 sites across 38 states)

Every actively recruiting Sonrotoclaxtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AL	University of Alabama At Birmingham Hospital	Birmingham35294-0004	NCT06742996	Map
AL	University of Alabama At Birmingham Hospital	Birmingham35294-0004	NCT04973605	Map
AZ	Mayo Clinic Phoenix	Phoenix85054-4502	NCT06634589	Map
AZ	University of Arizona Cancer Center	Tucson85724-0001	NCT06742996	Map
CA	City of Hope Medical Center	Duarte91010	NCT06859008	Map
CA	City of Hope National Medical Center	Duarte91010-3012	NCT04973605	Map
CA	Ucsf Fresno	Fresno93701	NCT06742996	Map
CA	City of Hope Irvine Lennar	Irvine92618-2377	NCT04973605	Map
CA	Kaiser Permanente Southern California	Irvine92618-3734	NCT06742996	Map
CA	Uci Health Laguna Hills	Laguna Hills92653	NCT06943872	Map
CA	Cedars-Sinai Medical Center	Los Angeles90048	NCT07321652	Map
CA	University of Southern California Norris Comprehensive	Los Angeles90033	NCT06634589	Map
CA	Chao Family Comprehensive Cancer Center	Orange92868-3201	NCT06943872	Map
CA	Stanford Cancer Institute	Palo Alto94304-2205	NCT07277231	Map
CA	Stanford Cancer Institute	Palo Alto94304-2205	NCT06943872	Map
CA	Scripps Prebys Cancer Center	San Diego92103-2106	NCT06943872	Map
CO	Rocky Mountain Cancer Centers (Williams) Usor	Aurora80012-5405	NCT06943872	Map
CT	Yale University Yale Cancer Center	New Haven06520-8028	NCT06742996	Map
CT	Yale University Yale Cancer Center	New Haven06520-8028	NCT06943872	Map
CT	Eastern Connecticut Hematology and Oncology	Norwich06360-2700	NCT06943872	Map
FL	Mayo Clinic Jacksonville	Jacksonville32224-1865	NCT06634589	Map
FL	Jupiter Medical Center	Jupiter33458	NCT07321652	Map
FL	University of Miami	Miami33136-2107	NCT04973605	Map
FL	Memorial Cancer Institute, Memorial Healthcare System	Pembroke Pines33026-4119	NCT06742996	Map
FL	Moffitt Cancer Center	Tampa33612-9496	NCT06634589	Map
FL	Cleveland Clinic Florida	Weston33331-3609	NCT06742996	Map
FL	Cleveland Clinic Florida	Weston33331-3609	NCT06943872	Map
GA	Emory University Winship Cancer Center	Atlanta30322-1013	NCT04973605	Map
ID	Saint Alphonsus Cancer Care Center-Boise	Boise83706	NCT07321652	Map
ID	Saint Alphonsus Cancer Care Center-Caldwell	Caldwell83605	NCT07321652	Map
ID	Kootenai Health - Coeur d'Alene	Coeur d'Alene83814	NCT07321652	Map
ID	Idaho Urologic Institute-Meridian	Meridian83642	NCT07321652	Map
ID	Saint Alphonsus Cancer Care Center-Nampa	Nampa83687	NCT07321652	Map
ID	Kootenai Clinic Cancer Services - Post Falls	Post Falls83854	NCT07321652	Map
ID	Kootenai Clinic Cancer Services - Sandpoint	Sandpoint83864	NCT07321652	Map
IL	Illinois CancerCare-Bloomington	Bloomington61704	NCT07321652	Map
IL	Illinois CancerCare-Canton	Canton61520	NCT07321652	Map
IL	Illinois CancerCare-Carthage	Carthage62321	NCT07321652	Map
IL	Northwestern University	Chicago60611	NCT07321652	Map
IL	Northwestern University	Chicago60611	NCT06943872	Map
IL	Rush University Medical Center	Chicago60607	NCT06742996	Map
IL	University of Chicago Medical Center	Chicago60637-1443	NCT06742996	Map
IL	University of Chicago Medical Center	Chicago60637-1443	NCT04973605	Map
IL	Carle at The Riverfront	Danville61832	NCT07321652	Map
IL	Cancer Care Specialists of Illinois - Decatur	Decatur62526	NCT07321652	Map
IL	Decatur Memorial Hospital	Decatur62526	NCT07321652	Map
IL	Illinois CancerCare-Dixon	Dixon61021	NCT07321652	Map
IL	Carle Physician Group-Effingham	Effingham62401	NCT07321652	Map
IL	Illinois CancerCare-Eureka	Eureka61530	NCT07321652	Map
IL	Illinois CancerCare-Galesburg	Galesburg61401	NCT07321652	Map
IL	Illinois CancerCare-Kewanee Clinic	Kewanee61443	NCT07321652	Map
IL	Illinois CancerCare-Macomb	Macomb61455	NCT07321652	Map
IL	Carle Physician Group-Mattoon/Charleston	Mattoon61938	NCT07321652	Map
IL	Illinois Cancer Specialists (Niles) Usor	Niles60714-5905	NCT06943872	Map
IL	Carle BroMenn Medical Center	Normal61761	NCT07321652	Map
IL	Carle Cancer Institute Normal	Normal61761	NCT07321652	Map
IL	Cancer Care Center of O'Fallon	O'Fallon62269	NCT07321652	Map
IL	HSHS Saint Elizabeth's Hospital	O'Fallon62269	NCT07321652	Map
IL	Illinois CancerCare-Ottawa Clinic	Ottawa61350	NCT07321652	Map
IL	Illinois CancerCare-Pekin	Pekin61554	NCT07321652	Map
IL	Illinois CancerCare-Peoria	Peoria61615	NCT07321652	Map
IL	Illinois CancerCare-Peru	Peru61354	NCT07321652	Map
IL	Illinois CancerCare-Princeton	Princeton61356	NCT07321652	Map
IL	Memorial Hospital East	Shiloh62269	NCT07321652	Map
IL	Southern Illinois University School of Medicine	Springfield62702	NCT07321652	Map
IL	Springfield Clinic	Springfield62702	NCT07321652	Map
IL	Springfield Memorial Hospital	Springfield62781	NCT07321652	Map
IL	Carle Cancer Center	Urbana61801	NCT07321652	Map
IL	Illinois CancerCare - Washington	Washington61571	NCT07321652	Map
IN	Fort Wayne Medical Oncology and Hematology	Fort Wayne46804	NCT06742996	Map
IA	UI Health Care Mission Cancer and Blood - Ankeny Clinic	Ankeny50023	NCT07321652	Map
IA	Saint Anthony Regional Hospital	Carroll51401	NCT07321652	Map
IA	Mercy Hospital	Cedar Rapids52403	NCT07321652	Map
IA	Oncology Associates at Mercy Medical Center	Cedar Rapids52403	NCT07321652	Map
IA	UI Health Care Mission Cancer and Blood - West Des Moines Clinic	Clive50325	NCT07321652	Map
IA	Broadlawns Medical Center	Des Moines50314	NCT07321652	Map
IA	Iowa Methodist Medical Center	Des Moines50309	NCT07321652	Map
IA	Mercy Medical Center - Des Moines	Des Moines50314	NCT07321652	Map
IA	UI Health Care Mission Cancer and Blood - Des Moines Clinic	Des Moines50309	NCT07321652	Map
IA	UI Health Care Mission Cancer and Blood - Laurel Clinic	Des Moines50314	NCT07321652	Map
IA	UI Healthcare Mission Cancer and Blood - Fort Dodge	Fort Dodge50501	NCT07321652	Map
IA	UI Healthcare Mission Cancer and Blood - Pella	Pella50219	NCT07321652	Map
IA	Mission Cancer and Blood	Waukee50263	NCT06742996	Map
IA	UI Health Care Mission Cancer and Blood - Waukee Clinic	Waukee50263	NCT07321652	Map
KS	Cancer Center of Kansas - Chanute	Chanute66720	NCT07321652	Map
KS	Cancer Center of Kansas - Dodge City	Dodge City67801	NCT07321652	Map
KS	Cancer Center of Kansas - El Dorado	El Dorado67042	NCT07321652	Map
KS	Cancer Center of Kansas-Independence	Independence67301	NCT07321652	Map
KS	University of Kansas Cancer Center	Kansas City66160	NCT07321652	Map
KS	Cancer Center of Kansas-Kingman	Kingman67068	NCT07321652	Map
KS	Cancer Center of Kansas-Liberal	Liberal67905	NCT07321652	Map
KS	Cancer Center of Kansas - McPherson	McPherson67460	NCT07321652	Map
KS	Cancer Center of Kansas - Newton	Newton67114	NCT07321652	Map
KS	The University of Kansas Cancer Center - Olathe	Olathe66061	NCT07321652	Map
KS	University of Kansas Cancer Center-Overland Park	Overland Park66210	NCT07321652	Map
KS	Cancer Center of Kansas - Parsons	Parsons67357	NCT07321652	Map
KS	Cancer Center of Kansas - Pratt	Pratt67124	NCT07321652	Map
KS	Cancer Center of Kansas - Salina	Salina67401	NCT07321652	Map
KS	University of Kansas Health System Saint Francis Campus	Topeka66606	NCT07321652	Map
KS	Cancer Center of Kansas - Wellington	Wellington67152	NCT07321652	Map
KS	The University of Kansas Cancer Center	Westwood66205-2003	NCT06634589	Map
KS	University of Kansas Hospital-Westwood Cancer Center	Westwood66205	NCT07321652	Map
KS	Ascension Via Christi Hospitals Wichita	Wichita67214	NCT07321652	Map
KS	Cancer Center of Kansas - Wichita	Wichita67214	NCT07321652	Map
KS	Cancer Center of Kansas-Wichita Medical Arts Tower	Wichita67208	NCT07321652	Map
KS	Cancer Center of Kansas - Winfield	Winfield67156	NCT07321652	Map
KY	The James Graham Brown Cancer Center at University of Louisville	Louisville40202	NCT07321652	Map
KY	University of Louisville, Brown Cancer Center	Louisville40202	NCT06943872	Map
KY	UofL Health Medical Center Northeast	Louisville40245	NCT07321652	Map
LA	Mary Bird Perkins Cancer Center	Baton Rouge70809-3738	NCT06943872	Map
LA	Our Lady of the Lake Hospital	Baton Rouge70808-4365	NCT06742996	Map
MD	The University of Maryland Greenebaum Comprehensive Cancer Center	Baltimore21201	NCT06742996	Map
MD	The University of Maryland Greenebaum Comprehensive Cancer Center	Baltimore21201	NCT06943872	Map
MA	Beth Israel Deaconess Medical Center	Boston02215	NCT06854003	Map
MA	Beth Israel Deaconess Medical Center (Bidmc)	Boston02215-5400	NCT06943872	Map
MA	Dana Farber Cancer Institute	Boston02215-5418	NCT06943872	Map
MA	Dana Farber Cancer Institute Longwood Medical Center	Boston02215-5418	NCT06742996	Map
MA	Dana-Farber Cancer Institute	Boston02215	NCT06854003	Map
MA	Massachusetts General Hospital	Boston02114	NCT06849713	Map
MI	University of Michigan	Ann Arbor48109-1382	NCT06742996	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Brighton	Brighton48114	NCT07321652	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Canton	Canton48188	NCT07321652	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital	Chelsea48118	NCT07321652	Map
MI	The Cancer and Hematology Centers	Grand Rapids49503-2563	NCT06742996	Map
MI	The Cancer and Hematology Centers	Grand Rapids49503-2563	NCT06943872	Map
MI	University of Michigan Health - Sparrow Lansing	Lansing48912	NCT07321652	Map
MI	Trinity Health Saint Mary Mercy Livonia Hospital	Livonia48154	NCT07321652	Map
MI	Trinity Health Saint Joseph Mercy Oakland Hospital	Pontiac48341	NCT07321652	Map
MI	Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus	Ypsilanti48197	NCT07321652	Map
MN	Sanford Joe Lueken Cancer Center	Bemidji56601	NCT07321652	Map
MN	Essentia Health Saint Joseph's Medical Center	Brainerd56401	NCT07321652	Map
MN	Mercy Hospital	Coon Rapids55433	NCT07321652	Map
MN	Essentia Health - Deer River Clinic	Deer River56636	NCT07321652	Map
MN	Essentia Health Cancer Center	Duluth55805	NCT07321652	Map
MN	Essentia Health Hibbing Clinic	Hibbing55746	NCT07321652	Map
MN	Abbott-Northwestern Hospital	Minneapolis55407	NCT07321652	Map
MN	Mayo Clinic Rochester	Rochester55905-0001	NCT06634589	Map
MN	Mayo Clinic Rochester	Rochester55905-0001	NCT06742996	Map
MN	Mayo Clinic Rochester	Rochester55905-0001	NCT06943872	Map
MN	Park Nicollet Clinic - Saint Louis Park	Saint Louis Park55416	NCT07321652	Map
MN	Regions Hospital	Saint Paul55101	NCT07321652	Map
MN	United Hospital	Saint Paul55102	NCT07321652	Map
MN	Essentia Health Sandstone	Sandstone55072	NCT07321652	Map
MN	Essentia Health Virginia Clinic	Virginia55792	NCT07321652	Map
MS	Hattiesburg Hematology and Oncology Clinic	Hattiesburg39401-7233	NCT06742996	Map
MS	Baptist Memorial Hospital and Cancer Center-Desoto	Southhaven38671	NCT07321652	Map
MO	Saint Francis Medical Center	Cape Girardeau63703	NCT07321652	Map
MO	Siteman Cancer Center at Saint Peters Hospital	City of Saint Peters63376	NCT07321652	Map
MO	Siteman Cancer Center at West County Hospital	Creve Coeur63141	NCT07321652	Map
MO	Parkland Health Center - Farmington	Farmington63640	NCT07321652	Map
MO	University of Kansas Cancer Center - Briarcliff	Kansas City64116	NCT07321652	Map
MO	University of Kansas Cancer Center - North	Kansas City64154	NCT07321652	Map
MO	University of Kansas Cancer Center - Lee's Summit	Lee's Summit64064	NCT07321652	Map
MO	Sainte Genevieve County Memorial Hospital	Sainte Genevieve63670	NCT07321652	Map
MO	Missouri Baptist Medical Center	St Louis63131	NCT07321652	Map
MO	Siteman Cancer Center at Christian Hospital	St Louis63136	NCT07321652	Map
MO	Siteman Cancer Center-South County	St Louis63129	NCT07321652	Map
MO	Washington University	St Louis63110	NCT06854003	Map
MO	Washington University School of Medicine	St Louis63110-1010	NCT06634589	Map
MO	Washington University School of Medicine	St Louis63110-1010	NCT06742996	Map
MO	Washington University School of Medicine	St Louis63110	NCT07321652	Map
MO	Washington University School of Medicine	St Louis63110-1010	NCT04973605	Map
MO	Missouri Baptist Sullivan Hospital	Sullivan63080	NCT07321652	Map
MT	Community Hospital of Anaconda	Anaconda59711	NCT07321652	Map
MT	Billings Clinic Cancer Center	Billings59101	NCT07321652	Map
MT	Bozeman Health Deaconess Hospital	Bozeman59715	NCT07321652	Map
MT	Benefis Sletten Cancer Institute	Great Falls59405	NCT07321652	Map
MT	Logan Health Medical Center	Kalispell59901	NCT07321652	Map
MT	Community Medical Center	Missoula59804	NCT07321652	Map
NE	Nebraska Cancer Specialists St Francis Grand Island	Grand Island68803	NCT06742996	Map
NE	Nebraska Cancer Specialists	Omaha68130-2042	NCT06742996	Map
NJ	Jefferson Cherry Hill Hospital	Cherry Hill08002	NCT07321652	Map
NJ	Summit Medical Group	Florham Park07932-1049	NCT06634589	Map
NJ	Hackensack University Medical Center	Hackensack07601-1915	NCT04973605	Map
NJ	The Valley Hospital, Inc	Paramus07652	NCT06742996	Map
NJ	Sidney Kimmel Cancer Center Washington Township	Sewell08080	NCT07321652	Map
NJ	Sidney Kimmel Comprehensive Cancer Center Washington Twp	Sewell08080	NCT06943872	Map
NM	Christus St Vincent Regional Cancer Center	Santa Fe87505	NCT06943872	Map
NY	Columbia University Medical Center	New York10032	NCT06634589	Map
NY	Icahn School of Medicine At Mount Sinai	New York10029-6504	NCT06634589	Map
NY	Memorial Sloan Kettering Cancer Center	New York10065	NCT06854003	Map
NY	Memorial Sloan Kettering Cancer Center Mskcc	New York10065-6800	NCT06634589	Map
NY	Memorial Sloan Kettering Cancer Center Mskcc	New York10065-6800	NCT06742996	Map
NY	Memorial Sloan Kettering Cancer Center Mskcc	New York10065-6800	NCT06943872	Map
NY	Memorial Sloan Kettering Cancer Center Mskcc	New York10065-6800	NCT04973605	Map
NY	Weill Cornell Medical College Newyork Presbyterian Hospital	New York10065-4870	NCT06634589	Map
NY	Weill Cornell Medical College Newyork Presbyterian Hospital	New York10065-4870	NCT04973605	Map
NY	University of Rochester	Rochester14642-0001	NCT06634589	Map
NY	University of Rochester	Rochester14642	NCT07321652	Map
NY	Wilmot Cancer Institute at Webster	Webster14580	NCT07321652	Map
NY	OPTUM	Westbury11590-5119	NCT06943872	Map
NC	UNC Lineberger Comprehensive Cancer Center	Chapel Hill27599	NCT07321652	Map
NC	University of North Carolina At Chapel Hill	Chapel Hill27514-4220	NCT06943872	Map
NC	Atrium Health Levine Cancer Institute (Lci)	Charlotte28204-2990	NCT06742996	Map
NC	Levine Cancer Center	Charlotte28204-2990	NCT06943872	Map
NC	Duke University	Durham27710	NCT06742996	Map
NC	Duke University Medical Center	Durham27710	NCT07321652	Map
NC	Margaret R Pardee Memorial Hospital	Hendersonville28791	NCT07321652	Map
NC	Atrium Health Wake Forest Baptist	Winston-Salem27157	NCT06742996	Map
NC	Atrium Health Wake Forest Baptist	Winston-Salem27157	NCT06943872	Map
ND	Sanford Bismarck Medical Center	Bismarck58501	NCT07321652	Map
ND	Essentia Health Cancer Center-South University Clinic	Fargo58103	NCT07321652	Map
ND	Sanford Broadway Medical Center	Fargo58122	NCT07321652	Map
ND	Sanford Roger Maris Cancer Center	Fargo58122	NCT07321652	Map
OH	Oncology Hematology Care Clinical Trials, Llc	Cincinnati45245-1995	NCT06943872	Map
OH	Cleveland Clinic Foundation	Cleveland44195-0001	NCT06742996	Map
OH	University Hospitals	Cleveland44106-1716	NCT06742996	Map
OH	Ohio Health Research Institute	Columbus43214-3907	NCT06742996	Map
OH	Ohio State University Comprehensive Cancer Center	Columbus43210-1280	NCT06742996	Map
OH	Ohio State University Comprehensive Cancer Center	Columbus43210	NCT07321652	Map
OH	The James Cancer Hospital and Solove Research Institute At Ohio State University	Columbus43210-1240	NCT04973605	Map
OK	University of Oklahoma Health Sciences Center	Oklahoma City73104	NCT07321652	Map
OR	Saint Alphonsus Cancer Care Center-Baker City	Baker City97814	NCT07321652	Map
OR	Oncology Associates of Oregon Willamette Valley Cancer Center	Eugene97401	NCT06943872	Map
OR	Providence Newberg Medical Center	Newberg97132	NCT07321652	Map
OR	Saint Alphonsus Cancer Care Center-Ontario	Ontario97914	NCT07321652	Map
OR	Providence Willamette Falls Medical Center	Oregon City97045	NCT07321652	Map
OR	Providence Portland Medical Center	Portland97213	NCT07321652	Map
OR	Providence Saint Vincent Medical Center	Portland97225	NCT07321652	Map
PA	Penn State Milton S Hershey Medical Center	Hershey17033	NCT06742996	Map
PA	Penn State Milton S Hershey Medical Center	Hershey17033	NCT06943872	Map
PA	Fox Chase Cancer Center	Philadelphia19111-2434	NCT06634589	Map
PA	Jefferson Torresdale Hospital	Philadelphia19114	NCT07321652	Map
PA	Thomas Jefferson University	Philadelphia19107-4216	NCT06943872	Map
PA	Thomas Jefferson University Hospital	Philadelphia19107	NCT07321652	Map
PA	Upmc Hillman Cancer Center(Univ of Pittsburgh)	Pittsburgh15232-1309	NCT06943872	Map
PA	McGlinn Cancer Institute	West Reading19611-2143	NCT06742996	Map
SD	Sanford Cancer Center Oncology Clinic	Sioux Falls57104	NCT07321652	Map
SD	Sanford USD Medical Center - Sioux Falls	Sioux Falls57117-5134	NCT07321652	Map
SD	Avera Cancer Institute at Yankton	Yankton57078	NCT07321652	Map
TN	Tennessee Oncology Greco Hainsworth Centers For Research Chattanooga	Chattanooga37404	NCT06943872	Map
TN	Baptist Memorial Hospital and Cancer Center-Collierville	Collierville38017	NCT07321652	Map
TN	Baptist Memorial Hospital and Cancer Center-Memphis	Memphis38120	NCT07321652	Map
TN	Tennessee Oncology	Nashville37205	NCT06742996	Map
TN	Tennessee Oncology	Nashville37205	NCT06943872	Map
TN	Tennessee Oncology Nashville St Thomas Midtown Clinic	Nashville37205	NCT06742996	Map
TX	Texas Oncology Baylorcharles A Sammons Cancer Center	Dallas75246-2003	NCT06943872	Map
TX	Md Anderson Cancer Center	Houston77030-3907	NCT06742996	Map
TX	The University of Texas Md Anderson Cancer Center	Houston77030-4009	NCT06634589	Map
TX	Texas Oncology Austin Midtown	Round Rock78681-4019	NCT06742996	Map
TX	Texas Oncology San Antonio Medical Center Usor	San Antonio78240-5251	NCT06943872	Map
TX	Texas Oncology Tyler	Tyler75702-7522	NCT06943872	Map
UT	Huntsman Cancer Institute	Salt Lake City84112-5550	NCT06634589	Map
UT	Huntsman Cancer Institute	Salt Lake City84112-5550	NCT04973605	Map
VA	University of Virginia	Charlottesville22908-0817	NCT06742996	Map
VA	Virgina Cancer Specialists	Gainesville20155-3257	NCT06742996	Map
VA	Vcu Massey Cancer Center	Richmond23298-5026	NCT06742996	Map
WA	Swedish Cancer Institute-Edmonds	Edmonds98026	NCT07321652	Map
WA	Swedish Cancer Institute-Issaquah	Issaquah98029	NCT07321652	Map
WA	Fred Hutch/University of Washington Cancer Consortium	Seattle98109	NCT06839053	Map
WA	Fred Hutchinson Cancer Research Center	Seattle98109-4433	NCT07277231	Map
WA	Swedish Medical Center-First Hill	Seattle98122	NCT07321652	Map
WA	University of Washington	Seattle98195	NCT04973605	Map
WA	Northwest Cancer Specialist, Pc(Us Oncology Research)	Vancouver98684-6930	NCT06742996	Map
WA	Northwest Cancer Specialist, Pc(Us Oncology Research)	Vancouver98684-6930	NCT06943872	Map
WI	Duluth Clinic Ashland	Ashland54806	NCT07321652	Map
WI	Saint Vincent Hospital Cancer Center at Saint Mary's	Green Bay54303	NCT07321652	Map
WI	Saint Vincent Hospital Cancer Center Green Bay	Green Bay54301	NCT07321652	Map
WI	Gundersen Lutheran Medical Center	La Crosse54601	NCT07321652	Map
WI	University of Wisconsin	Madison53792-0001	NCT06634589	Map
WI	University of Wisconsin	Madison53792-0001	NCT06742996	Map
WI	University of Wisconsin Carbone Cancer Center	Madison53792-0001	NCT04973605	Map
WI	William S Middleton VA Medical Center	Madison53705	NCT07321652	Map
WI	Medical College of Wisconsin	Milwaukee53226-3522	NCT06634589	Map
WI	Medical College of Wisconsin	Milwaukee53226-3522	NCT04973605	Map
WI	ProHealth D N Greenwald Center	Mukwonago53149	NCT07321652	Map
WI	ProHealth Oconomowoc Memorial Hospital	Oconomowoc53066	NCT07321652	Map
WI	Saint Vincent Hospital Cancer Center at Oconto Falls	Oconto Falls54154	NCT07321652	Map
WI	Saint Vincent Hospital Cancer Center at Sturgeon Bay	Sturgeon Bay54235-1495	NCT07321652	Map
WI	UW Cancer Center at ProHealth Care	Waukesha53188	NCT07321652	Map

Sonrotoclax clinical trials at a glance: phase × recruitment status

Phase	recruiting	active not recruiting	completed	not yet recruiting	Total
P1	1	1	2	1	5
P1/P2	3				3
P2	6	3		2	11
P3	4	1			5

Recruiting Sonrotoclax clinical trials (17)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT06854003	BRAZANBRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma	P2	Mantle Cell Lymphoma	60	Apr 2025
NCT07321652	Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL	P3	Chronic Lymphocytic Leukemia	466	Apr 2026
NCT06697184	A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.	P1/P2	Chronic Lymphocytic Leukemia	258	Jan 2025
NCT06839053	Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma	P2	Chronic Lymphocytic Leukemia	30	Jun 2025
NCT06742996	CELESTIAL-RRMCLA Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)	P3	Mantle Cell Lymphoma	300	Mar 2025
NCT06943872	CELESTIAL-RRCLLA Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)	P3	Chronic Lymphocytic Leukemia	630	Jun 2025
NCT07277231	BGB-11417A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia	P3	Chronic Lymphocytic Leukemia	500	Jan 2026
NCT07341191	Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy	P2	Mantle Cell Lymphoma	40	Jun 2026
NCT06367374	MRD Guided Sonrotoclax and Zanubrutinib in Newly Diagnosed CLL/SLL	P2	Chronic Lymphocytic Leukemia	66	May 2024
NCT06849713	BOSonZanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL	P2	Chronic Lymphocytic Leukemia	40	May 2025
NCT06634589	A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies	P1/P2	B-cell Malignancy	80	Nov 2024
NCT07548255	The Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined With Obinutuzumab in MCL	P1	Intermediate-to-High-Risk Mantle Cell Lymphoma	28	Apr 2026
NCT07335887	Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis	P2	AL Amyloidosis (AL)	39	Jan 2026
NCT06859008	Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma	P1	Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma	37	Aug 2025
NCT07548710	Study of SA+X in the Treatment of Newly Diagnosed AML	P2	Acute Myeloid Leukemia	205	May 2026
NCT04973605	BGB-11417A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma	P1/P2	Relapsed/Refractory Multiple Myeloma	246	Sep 2021
NCT04271956	CLL-RT1Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment with or Without Sonrotoclax for Patients with Richter Transformation	P2	Richter Transformation	83	Feb 2020

Sonrotoclax clinical trials by indication

Chronic Lymphocytic Leukemia (8)

NCT	Acronym	Phase	Status	Title
NCT07321652	—	P3	recruiting	Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
NCT06697184	—	P1/P2	recruiting	A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.
NCT06839053	—	P2	recruiting	Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma
NCT06943872	CELESTIAL-RRCLL	P3	recruiting	A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
NCT07277231	BGB-11417	P3	recruiting	A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia
NCT06367374	—	P2	not yet recruiting	MRD Guided Sonrotoclax and Zanubrutinib in Newly Diagnosed CLL/SLL
NCT06849713	BOSon	P2	recruiting	Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL
NCT06637501	—	P2	active not recruiting	A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia

Mantle Cell Lymphoma (3)

NCT	Acronym	Phase	Status	Title
NCT06854003	BRAZAN	P2	recruiting	BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma
NCT06742996	CELESTIAL-RRMCL	P3	recruiting	A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
NCT07341191	—	P2	recruiting	Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

Acute Myeloid Leukemia (2)

NCT	Acronym	Phase	Status	Title
NCT07548710	—	P2	recruiting	Study of SA+X in the Treatment of Newly Diagnosed AML
NCT06497062	—	P2	active not recruiting	Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia

Intermediate-to-High-Risk Mantle Cell Lymphoma (1)

NCT	Acronym	Phase	Status	Title
NCT07548255	—	P1	not yet recruiting	The Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined With Obinutuzumab in MCL

AL Amyloidosis (AL) (1)

NCT	Acronym	Phase	Status	Title
NCT07335887	—	P2	not yet recruiting	Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis

Healthy Volunteers (1)

NCT	Acronym	Phase	Status	Title
NCT07141511	BG-71332	P1	completed	A Study to Investigate the Relative Bioavailability and Food Effect of a Fixed-Dose Combination Tablet Containing Zanubrutinib and Sonrotoclax (BG-71332) in Healthy Adults

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (1)

NCT	Acronym	Phase	Status	Title
NCT06859008	—	P1	recruiting	Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

B-cell Malignancy (1)

NCT	Acronym	Phase	Status	Title
NCT06634589	—	P1/P2	recruiting	A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Not Determined (1)

NCT	Acronym	Phase	Status	Title
NCT06543043	BGB-11417	P1	completed	A Study to Evaluate the Effects of Phenytoin and Itraconazole on Sonrotoclax (BGB-11417) in Healthy Volunteers

CLL (1)

NCT	Acronym	Phase	Status	Title
NCT06073821	BGB-11417	P3	active not recruiting	Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Waldenstrom Macroglobulinemia (1)

NCT	Acronym	Phase	Status	Title
NCT05952037	—	P2	active not recruiting	A Study to Investigate Efficacy and Safety of BCL2 Inhibitor Sonrotoclax as Monotherapy and in Combination With Zanubrutinib in Adults With Waldenström Macroglobulinemia

Relapsed/Refractory Multiple Myeloma (1)

NCT	Acronym	Phase	Status	Title
NCT04973605	BGB-11417	P1/P2	recruiting	A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Mature B-Cell Malignancies (1)

NCT	Acronym	Phase	Status	Title
NCT04277637	BGB-11417	P1	active not recruiting	Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies

Richter Transformation (1)

NCT	Acronym	Phase	Status	Title
NCT04271956	CLL-RT1	P2	recruiting	Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment with or Without Sonrotoclax for Patients with Richter Transformation

Sonrotoclax pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
BGB-11417	NCT06073821	P3	active not recruiting	CLL	652	—
CELESTIAL-RRMCL	NCT06742996	P3	recruiting	Mantle Cell Lymphoma	300	—
CELESTIAL-RRCLL	NCT06943872	P3	recruiting	Chronic Lymphocytic Leukemia	630	—
BGB-11417	NCT07277231	P3	recruiting	Chronic Lymphocytic Leukemia	500	—
BRAZAN	NCT06854003	P2	recruiting	Mantle Cell Lymphoma	60	—
BOSon	NCT06849713	P2	recruiting	Chronic Lymphocytic Leukemia	40	—
CLL-RT1	NCT04271956	P2	recruiting	Richter Transformation	83	PMID 38071379

All Sonrotoclax trials (24)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT06854003	BRAZAN	BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma	P2	recruiting	60	Christine Ryan	Apr 2025
NCT07321652		Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL	P3	recruiting	466	Alliance for Clinical Trials in Oncology	Apr 2026
NCT06073821	BGB-11417	Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)	P3	active not recruiting	652	BeOne Medicines	Nov 2023
NCT06697184		A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.	P1/P2	recruiting	258	BeOne Medicines	Jan 2025
NCT06839053		Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma	P2	recruiting	30	Fred Hutchinson Cancer Center	Jun 2025
NCT06742996	CELESTIAL-RRMCL	A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)	P3	recruiting	300	BeOne Medicines	Mar 2025
NCT06943872	CELESTIAL-RRCLL	A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)	P3	recruiting	630	BeOne Medicines	Jun 2025
NCT07277231	BGB-11417	A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia	P3	recruiting	500	BeOne Medicines	Jan 2026
NCT07341191		Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy	P2	recruiting	40	Canadian Cancer Trials Group	Jun 2026
NCT06367374		MRD Guided Sonrotoclax and Zanubrutinib in Newly Diagnosed CLL/SLL	P2	not yet recruiting	66	Institute of Hematology & Blood Diseases Hospital, China	May 2024
NCT06849713	BOSon	Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL	P2	recruiting	40	Massachusetts General Hospital	May 2025
NCT06634589		A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies	P1/P2	recruiting	80	BeOne Medicines	Nov 2024
NCT06637501		A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia	P2	active not recruiting	94	BeOne Medicines	Nov 2024
NCT07548255		The Efficacy and Safety of Sonrotoclax, Zanubrutinib Combined With Obinutuzumab in MCL	P1	not yet recruiting	28	Ruijin Hospital	Apr 2026
NCT07335887		Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis	P2	not yet recruiting	39	Peking University People's Hospital	Jan 2026
NCT06859008		Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma	P1	recruiting	37	City of Hope Medical Center	Aug 2025
NCT07548710		Study of SA+X in the Treatment of Newly Diagnosed AML	P2	recruiting	205	Ruijin Hospital	May 2026
NCT05952037		A Study to Investigate Efficacy and Safety of BCL2 Inhibitor Sonrotoclax as Monotherapy and in Combination With Zanubrutinib in Adults With Waldenström Macroglobulinemia	P2	active not recruiting	114	BeOne Medicines	Oct 2023
NCT06497062		Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemia	P2	active not recruiting	47	Shanghai Jiao Tong University School of Medicine	Oct 2024
NCT04277637	BGB-11417	Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies	P1	active not recruiting	437	BeOne Medicines	Mar 2020
NCT04973605	BGB-11417	A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma	P1/P2	recruiting	246	BeOne Medicines	Sep 2021
NCT04271956	CLL-RT1	Efficacy and Safety of Zanubrutinib Plus Tislelizumab Treatment with or Without Sonrotoclax for Patients with Richter Transformation	P2	recruiting	83	German CLL Study Group	Feb 2020
NCT07141511	BG-71332	A Study to Investigate the Relative Bioavailability and Food Effect of a Fixed-Dose Combination Tablet Containing Zanubrutinib and Sonrotoclax (BG-71332) in Healthy Adults	P1	completed	24	BeOne Medicines	Sep 2025
NCT06543043	BGB-11417	A Study to Evaluate the Effects of Phenytoin and Itraconazole on Sonrotoclax (BGB-11417) in Healthy Volunteers	P1	completed	30	BeiGene	Aug 2024

Sonrotoclax clinical trials: frequently asked questions

How many Sonrotoclax clinical trials are there?: 24 Sonrotoclax clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 14 are actively recruiting participants. 2 are marked completed.
Are Sonrotoclax clinical trials recruiting in 2026?: Yes — 14 Sonrotoclax trials are actively recruiting in 2026, with 270 U.S. sites across 38 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Sonrotoclax being studied for?: Sonrotoclax is being studied for Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Small Lymphocytic Lymphoma, Acute Myeloid Leukemia, Refractory Mantle Cell Lymphoma and 43 more. The trials are grouped by indication on this page.
What phase is Sonrotoclax in?: Sonrotoclax clinical trials span 5 Phase 3, 11 Phase 2, 5 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Sonrotoclax clinical trials?: The lead sponsor across the most Sonrotoclax trials is BeOne Medicines, with 12 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Sonrotoclaxas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed July 17, 2026.

Related pages on Hipa.ai:

Sonrotoclax overview Sonrotoclax evidence & publications