Tapinarof Clinical Trials (2026): 19 Studies for Plaque Psoriasis & Atopic Dermatitis
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
19 Tapinarof clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 7 indications (including Plaque Psoriasis & Atopic Dermatitis) and 4,920 total planned enrollment. 9 Phase 3 Tapinarof trials and 3 Phase 2, 4 Phase 4 are listed. 4 Tapinarof clinical trials are actively recruiting at 36 U.S. sites across 24 states. Most recent activity: NCT07352566 (Jun 2030).
Where to Participate: All Tapinarof Trial Sites in the U.S. (36 sites across 24 states)
Every actively recruiting Tapinaroftrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AL | AllerVie Clinical Research | Birmingham35209 | NCT07265479 | Map |
| AR | Dermatology Trial Associates | Bryant72022 | NCT07265479 | Map |
| CA | Dermatology Research Associates | Los Angeles90045 | NCT07265479 | Map |
| CA | Integrative Skin Science and Research | Sacramento95815 | NCT07265479 | Map |
| CA | Allergy and Asthma Medical Group and Research Center | San Diego92123 | NCT07265479 | Map |
| CA | Clinical Trials Research Institute | Thousand Oaks91320 | NCT07265479 | Map |
| CO | Clarity Dermatology | Castle Rock80109 | NCT07265479 | Map |
| FL | Skin Care Research, LLC. | Boca Raton33486 | NCT07265479 | Map |
| FL | APEX Clinical Trials | Jacksonville32256 | NCT07265479 | Map |
| FL | TruDerm Research | Wellington33449 | NCT07265479 | Map |
| GA | Cleaver Medical Group Dermatology, Inc | Cumming30040 | NCT07265479 | Map |
| ID | Ada West Research | Meridian83646 | NCT07265479 | Map |
| IL | Endeavor Health Clinical Trials Center | Skokie60077 | NCT07265479 | Map |
| IN | Dawes Fretzin Clinical Research Group, LLC | Indianapolis46250 | NCT07265479 | Map |
| IN | The Indiana Clinical Trials Center, PC | Plainfield46168 | NCT07265479 | Map |
| KY | Equity Medical, LLC | Bowling Green42104 | NCT07265479 | Map |
| MD | Lawrence J Green, MD LLC | Rockville20850 | NCT07265479 | Map |
| MI | Oakland Hills Dermatology | Auburn Hills48326 | NCT07265479 | Map |
| MN | Minnesota Clinical Study Center | New Brighton55112 | NCT07265479 | Map |
| MS | SKY Integrative Medical Center | Ridgeland39157 | NCT07265479 | Map |
| MO | MediSearch Clinical Trials | Saint Joseph64506 | NCT07265479 | Map |
| NV | Skin Cancer and Dermatology Institute | Reno89509 | NCT07265479 | Map |
| NY | Forest Hills Dermatology Group | Kew Gardens11415 | NCT07265479 | Map |
| NY | Bobby Buka MD, PC | New York10012 | NCT07265479 | Map |
| NY | Equity Medical, LLC | The Bronx10455 | NCT07265479 | Map |
| NC | The University of North Carolina Dermatology and Skin Cancer Center | Chapel Hill27516 | NCT07265479 | Map |
| OH | Dermatologists of Central States, LLC | Fairborn45324 | NCT07265479 | Map |
| OK | Allergy Asthma and Clinical Research Center | Oklahoma City73120 | NCT07265479 | Map |
| OR | Oregon Dermatology and Research Center | Portland97210 | NCT07265479 | Map |
| OR | Oregon Health & Science University | Portland97239 | NCT07265479 | Map |
| SC | Medical University of South Carolina | Charleston29425 | NCT07265479 | Map |
| SC | National Allergy and Asthma Research, LLC. | North Charleston29420 | NCT07265479 | Map |
| TX | The University of Texas Health Science Center at Houston | Bellaire77401 | NCT07265479 | Map |
| TX | Dermatology Treatment and Research Center | Dallas75230 | NCT07265479 | Map |
| TX | Stryde Research - Epiphany Dermatology | Southlake76092 | NCT07265479 | Map |
| WA | Dermatology Specialists of Spokane | Spokane99202 | NCT07265479 | Map |
Tapinarof clinical trials at a glance: phase × recruitment status
| Phase | recruiting | active not recruiting | enrolling by invitation | completed | not yet recruiting | Total |
|---|---|---|---|---|---|---|
| Early P1 | 1 | 1 | ||||
| P1 | 1 | 1 | ||||
| P2 | 1 | 2 | 3 | |||
| P2/P3 | 1 | 1 | ||||
| P3 | 1 | 1 | 7 | 9 | ||
| P4 | 3 | 1 | 4 |
Recruiting Tapinarof clinical trials (4)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT07352566 | Utilization of a Microdevice for Psoriasis and Atopic Dermatitis | P4 | Psoriasis | 10 | Aug 2026 |
| NCT07265479 | AdoringA Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis | P3 | Atopic Dermatitis | 180 | Dec 2025 |
| NCT06661213 | Tapinarof for Cutaneous Lupus Erythematosus | Early P1 | Cutaneous Lupus Erythematosus | 10 | Apr 2025 |
| NCT05981118 | Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant) | P2/P3 | ICD10 Code L40.9 for Psoriasis | 40 | Jul 2024 |
Tapinarof clinical trials by indication
Plaque Psoriasis (6)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05172726 | — | P3 | active not recruiting | Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects |
| NCT07546214 | — | P1 | completed | A Study Comparing Tapinarof Cream 1% and Vtama® Cream 1% in the Treatment of Plaque Psoriasis. |
| NCT04053387 | — | P3 | completed | Long Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003) |
| NCT03983980 | — | P3 | completed | Tapinarof for the Treatment of Plaque Psoriasis in Adults (3002) |
| NCT03956355 | — | P3 | completed | Tapinarof for the Treatment of Plaque Psoriasis in Adults (3001) |
| NCT04042103 | — | P2 | completed | Maximal Use Study of Tapinarof Cream, 1% in Adults With Extensive Plaque Psoriasis |
Atopic Dermatitis (5)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07265479 | Adoring | P3 | recruiting | A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis |
| NCT05142774 | — | P3 | completed | Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis |
| NCT05014568 | — | P3 | completed | Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults |
| NCT05032859 | DMVT-505-3102 | P3 | completed | Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102) |
| NCT05186805 | — | P2 | completed | Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis |
Psoriasis (4)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07352566 | — | P4 | not yet recruiting | Utilization of a Microdevice for Psoriasis and Atopic Dermatitis |
| NCT06103695 | — | P4 | completed | Vtama in Psoriasis Patients Being Treated With Biologics. |
| NCT05789576 | — | P4 | completed | A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region |
| NCT05680740 | — | P4 | completed | A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis |
Cutaneous Lupus Erythematosus (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06661213 | — | Early P1 | enrolling by invitation | Tapinarof for Cutaneous Lupus Erythematosus |
Plaque Type Psorisis (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06742957 | — | P3 | completed | Study Comparing Tapinarof Cream 1% To VTAMA ® (Tapinarof Cream 1%) In the Treatment of Plaque Psoriasis |
Palmoplantar Keratoderma (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06561321 | — | P2 | active not recruiting | Study to Evaluate the Safety and Efficacy of Tapinarof in Adults With Palmoplantar Keratoderma |
ICD10 Code L40.9 for Psoriasis (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05981118 | — | P2/P3 | enrolling by invitation | Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant) |
Tapinarof pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| Adoring | NCT07265479 | P3 | recruiting | Atopic Dermatitis | 180 | — |
| DMVT-505-3102 | NCT05032859 | P3 | completed | Atopic Dermatitis | 406 | PMID 38777187 |
All Tapinarof trials (19)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT07352566 | Utilization of a Microdevice for Psoriasis and Atopic Dermatitis | P4 | not yet recruiting | 10 | University of California, San Francisco | Aug 2026 | |
| NCT07265479 | Adoring | A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis | P3 | recruiting | 180 | Organon and Co | Dec 2025 |
| NCT06561321 | Study to Evaluate the Safety and Efficacy of Tapinarof in Adults With Palmoplantar Keratoderma | P2 | active not recruiting | 6 | Indiana University | Oct 2024 | |
| NCT06661213 | Tapinarof for Cutaneous Lupus Erythematosus | Early P1 | enrolling by invitation | 10 | Northwestern University | Apr 2025 | |
| NCT05981118 | Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant) | P2/P3 | enrolling by invitation | 40 | Wake Forest University Health Sciences | Jul 2024 | |
| NCT05172726 | Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects | P3 | active not recruiting | 58 | Organon and Co | Dec 2021 | |
| NCT07546214 | A Study Comparing Tapinarof Cream 1% and Vtama® Cream 1% in the Treatment of Plaque Psoriasis. | P1 | completed | 575 | Sun Pharmaceutical Industries, Inc. | Oct 2025 | |
| NCT06742957 | Study Comparing Tapinarof Cream 1% To VTAMA ® (Tapinarof Cream 1%) In the Treatment of Plaque Psoriasis | P3 | completed | 560 | Teva Pharmaceuticals USA | Dec 2024 | |
| NCT05142774 | Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis | P3 | completed | 728 | Organon and Co | Oct 2021 | |
| NCT06103695 | Vtama in Psoriasis Patients Being Treated With Biologics. | P4 | completed | 30 | Psoriasis Treatment Center of Central New Jersey | Feb 2023 | |
| NCT05789576 | A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region | P4 | completed | 31 | Organon and Co | Mar 2023 | |
| NCT05680740 | A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis | P4 | completed | 34 | Organon and Co | Dec 2022 | |
| NCT05014568 | Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults | P3 | completed | 407 | Organon and Co | Sep 2021 | |
| NCT05032859 | DMVT-505-3102 | Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102) | P3 | completed | 406 | Organon and Co | Sep 2021 |
| NCT05186805 | Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis | P2 | completed | 36 | Organon and Co | Nov 2021 | |
| NCT04053387 | Long Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003) | P3 | completed | 763 | Organon and Co | Aug 2019 | |
| NCT03983980 | Tapinarof for the Treatment of Plaque Psoriasis in Adults (3002) | P3 | completed | 515 | Organon and Co | Jun 2019 | |
| NCT03956355 | Tapinarof for the Treatment of Plaque Psoriasis in Adults (3001) | P3 | completed | 510 | Organon and Co | May 2019 | |
| NCT04042103 | Maximal Use Study of Tapinarof Cream, 1% in Adults With Extensive Plaque Psoriasis | P2 | completed | 21 | Organon and Co | Jul 2019 |
Tapinarof clinical trials: frequently asked questions
- How many Tapinarof clinical trials are there?
- 19 Tapinarof clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 3 are actively recruiting participants. 13 are marked completed.
- Are Tapinarof clinical trials recruiting in 2026?
- Yes — 3 Tapinarof trials are actively recruiting in 2026, with 36 U.S. sites across 24 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is Tapinarof being studied for?
- Tapinarof is being studied for Plaque Psoriasis, Atopic Dermatitis, Psoriasis, Plaque Type Psorisis, Palmoplantar Keratoderma and 2 more. The trials are grouped by indication on this page.
- What phase is Tapinarof in?
- Tapinarof clinical trials span 4 Phase 4, 9 Phase 3, 3 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors Tapinarof clinical trials?
- The lead sponsor across the most Tapinarof trials is Organon and Co, with 7 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Tapinarofas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
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