City of Hope Orange County Lennar Foundation Cancer Center

Clinical research site in Irvine, California

Part of City of Hope

As of July 2026, 10 paid clinical trials are recruiting at City of Hope Orange County Lennar Foundation Cancer Center in Irvine, California. Active studies at this site cover conditions such as Multiple Myeloma, Breast Neoplasms and Carcinoma, Non-Small-Cell Lung. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Recruiting clinical trials at City of Hope Orange County Lennar Foundation Cancer Center (10)

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting·Listed Dec 2025

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

116 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting·Listed Sep 2025

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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

129 locations incl. Daphne

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting·Listed Oct 2024

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A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

66 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting·Listed Sep 2022

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A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

for Nausea

20 locations incl. Greenbrae

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07169851·Phase 2·Recruiting·Listed Sep 2025

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Study of XB010 in Subjects With Solid Tumors

for Locally Advanced or Metastatic Solid Tumors

16 locations incl. Irvine

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06545331·Phase 1·Recruiting·Listed Aug 2024

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AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)

5 locations incl. Irvine

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07403721·Phase 1·Recruiting·Listed Feb 2026

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

for Relapsed or Refractory Multiple Myeloma

9 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05652335·Phase 1·Recruiting·Listed Dec 2022

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Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

for Prostate Cancer

3 locations incl. Duarte

Sponsor: Varian, a Siemens Healthineers Company

Sex: Male·Age: 18+

Code: NCT05804318·Recruiting·Listed Apr 2023

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Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

for Recurrent Grade 1 Follicular Lymphoma

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06453044·Phase 2·Recruiting·Listed Jun 2024

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More research sites in Irvine

City of Hope at Irvine Lennar (57 trials)
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care (54 trials)
University of California, Irvine (34 trials)
University of California Irvine (19 trials)
Kaiser Permanente-Irvine (18 trials)
City of Hope - Orange County Lennar Foundation Cancer Center (10 trials)
City of Hope (8 trials)
Irvine Clinical Research (6 trials)
Beckman Laser Institute and Medical Clinic (4 trials)
Chao Family Comprehensive Cancer Center and Ambulatory Care (4 trials)

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Paid clinical trials in Irvine, CA · California clinical trials