Upmc Children'S Hospital of Pittsburgh

Clinical research site in Pittsburgh, Pennsylvania · 3705 5TH AVE, GROUND FLOOR, PITTSBURGH, PA 15213 · (412) 692-5352 · Website

As of July 2026, 73 paid clinical trials are recruiting at Upmc Children'S Hospital of Pittsburgh in Pittsburgh, Pennsylvania. Active studies at this site cover conditions such as Fabry Disease, Congenital Bone Marrow Failure Syndromes and Diabetes in Adolescence. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Recruiting clinical trials at Upmc Children'S Hospital of Pittsburgh (73)

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for Healthy

122 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 1 Day - 49·Accepts healthy volunteers

Code: NCT07160244·Phase 3·Recruiting·Listed Sep 2025

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Pompe Disease Registry Protocol

for Glycogen Storage Disease Type II

74 locations incl. Birmingham

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00231400·Recruiting·Listed Oct 2005

Apply to this trial

Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

74 locations incl. Birmingham

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting·Listed Sep 2005

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Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

for Allergy

56 locations incl. Birmingham

Sponsor: DBV Technologies

Sex: All·Age: 1 - 3

Code: NCT07003919·Phase 3·Recruiting·Listed Jun 2025

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A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

for Migraine

26 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT06616194·Phase 3·Recruiting·Listed Sep 2024

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A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

for Neoplasms

25 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 39

Code: NCT05999994·Phase 2·Recruiting·Listed Aug 2023

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International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

70 locations incl. Phoenix

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting·Listed Aug 2006

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COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

for Complex Congenital Heart Defect

19 locations incl. Little Rock

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT02744677·Recruiting·Listed Apr 2016

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EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

for COVID-19

24 locations incl. Los Angeles

Sponsor: Pfizer

Sex: All·Age: 0 - 17

Code: NCT05261139·Phase 3·Recruiting·Listed Mar 2022

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Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

37 locations incl. Phoenix

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023

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A Gaucher Disease Gene Therapy Trial With FLT201

for Gaucher Disease Type 1

16 locations incl. Los Angeles

Sponsor: Spur Therapeutics

Sex: All·Age: 18+

Code: NCT07223944·Phase 3·Recruiting·Listed Nov 2025

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SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes

for Type 1 Diabetes

23 locations incl. San Francisco

Sponsor: SAb Biotherapeutics, Inc.

Sex: All·Age: 5 - 40

Code: NCT07187531·Phase 2·Recruiting·Listed Sep 2025

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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

for Ulcerative Colitis

11 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT07071519·Phase 3·Recruiting·Listed Jul 2025

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A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

for Chronic Graft-versus-host-disease

11 locations incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 17

Code: NCT07124078·Phase 2·Recruiting·Listed Aug 2025

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Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

for Primary Mitochondrial Disease

20 locations incl. Orange

Sponsor: Pharming Technologies B.V.

Sex: All·Age: 18+

Code: NCT05650229·Phase 2·Recruiting·Listed Dec 2022

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A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

for Obesity

16 locations incl. Ventura

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT06672549·Phase 3·Recruiting·Listed Nov 2024

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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

for Heart Failure

20 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 29 Days - 17

Code: NCT05714085·Phase 2, Phase 3·Recruiting·Listed Feb 2023

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Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

for Lymphatic Malformations

18 locations incl. Oakland

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT05948943·Phase 2, Phase 3·Recruiting·Listed Jul 2023

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A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

for Crohn's Disease (CD)

15 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT04779320·Phase 3·Recruiting·Listed Mar 2021

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A Global Prospective Observational Registry of Patients With Pompe Disease

for Pompe Disease

15 locations incl. Little Rock

Sponsor: Amicus Therapeutics

Sex: All·Age: All ages

Code: NCT06121011·Recruiting·Listed Nov 2023

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Minima Stent System Post- Approval Study (PAS)

for Pulmonary Artery Stenosis

15 locations incl. Los Angeles

Sponsor: Renata Medical

Sex: All·Age: All ages

Code: NCT06828770·Recruiting·Listed Feb 2025

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Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

for Opioid-Induced Respiratory Depression

2 locations incl. San Francisco

Sponsor: NeurOptics Inc

Sex: All·Age: 3 - 17·Accepts healthy volunteers

Code: NCT07573150·Recruiting·Listed May 2026

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A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria

for Phenylketonuria

3 locations incl. Indianapolis

Sponsor: Agios Pharmaceuticals, Inc.

Sex: All·Age: 18 - 69

Code: NCT07241234·Phase 1·Recruiting·Listed Nov 2025

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A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition

for X-Linked Myotubular Myopathy

6 locations incl. Chicago

Sponsor: Astellas Gene Therapies

Sex: Male·Age: Up to 17

Code: NCT06581146·Recruiting·Listed Sep 2024

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Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

for Juvenile Psoriatic Arthritis

8 locations incl. Gainesville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 17

Code: NCT06751238·Phase 1·Recruiting·Listed Dec 2024

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EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

for PIK3CA-related Overgrowth Spectrum (PROS)

6 locations incl. St Louis

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 100

Code: NCT06997588·Phase 2·Recruiting·Listed May 2025

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A Study of Patients With Fabry Disease (US Specific)

for Fabry Disease

8 locations incl. Birmingham

Sponsor: Amicus Therapeutics

Sex: All·Age: 18+

Code: NCT06906367·Recruiting·Listed Apr 2025

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A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants

for Fabry Disease

6 locations incl. Atlanta

Sponsor: Amicus Therapeutics

Sex: All·Age: 2 - 11

Code: NCT06904261·Phase 3·Recruiting·Listed Apr 2025

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Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease

for Fabry Disease

8 locations incl. Birmingham

Sponsor: UniQure Biopharma B.V.

Sex: Male·Age: 18 - 50

Code: NCT06270316·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

for Patient-Reported Outcome Measures (PROMs)

14 locations incl. Stanford

Sponsor: Carelon Research

Sex: All·Age: 12 - 17

Code: NCT07525843·Recruiting·Listed Apr 2026

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Spinal Cord Stimulation for Children With Cerebral Palsy

for Cerebral Palsy

1 location in Pittsburgh

Sponsor: Martin Piazza

Sex: All·Age: 5 - 17·Accepts healthy volunteers

Code: NCT07516067·Recruiting·Listed Apr 2026

Apply to this trial

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

for Common Variable Immunodeficiency (CVID)

1 location in Pittsburgh

Sponsor: Paul Szabolcs

Sex: All·Age: 5 - 40

Code: NCT07284641·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

113 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

Apply to this trial

Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 16 - 24

Code: NCT07270016·Recruiting·Listed Dec 2025

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Pollution Intervention to Impact Kids Asthma Study

for Childhood Asthma

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 8 - 17

Code: NCT07261423·Recruiting·Listed Dec 2025

Apply to this trial

I-DECIDE After Bronchiolitis Hospitalization

for Bronchiolitis Acute

56 locations incl. Birmingham

Sponsor: Seattle Children's Hospital

Sex: All·Age: 0 Months - 24 Months

Code: NCT07243652·Recruiting·Listed Nov 2025

Apply to this trial

Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs

for Diabetes in Adolescence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT07216118·Recruiting·Listed Oct 2025

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Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

for Congenital Disorders of Glycosylation

12 locations incl. San Diego

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: All ages

Code: NCT04199000·Recruiting·Listed Dec 2019

Apply to this trial

Childhood Cancer Survivor Study

for Cancer

27 locations incl. Birmingham

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

Apply to this trial

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

for Crohn Disease

21 locations incl. Phoenix

Sponsor: Connecticut Children's Medical Center

Sex: All·Age: 6 - 17

Code: NCT05781152·Phase 4·Recruiting·Listed Mar 2023

Apply to this trial

Showing the 40 most relevant of 73 recruiting trials at this site. Browse all with filters →

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Paid clinical trials in Pittsburgh, PA · Pennsylvania clinical trials