Clinical Trials at University of Michigan

As of September 2026, 352 paid clinical trials are recruiting at University of Michigan, located at 1500 E MEDICAL CENTER DR, ANN ARBOR, MI 48109-5000, phone (734) 615-9888 in Ann Arbor, Michigan. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 21, 2026.

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356 clinical trials at University of Michigan

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Belimumab With Rituximab for Primary Membranous Nephropathy

for Membranous Nephropathy

Drug: Rituximab

Sites in Ann Arbor +19 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 75

Code: NCT03949855·Phase 2·Recruiting·Listed May 2019

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Home Transcutaneous Electrical Acustimulation (TEA)

for Irritable Bowel Syndrome With Constipation

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT05519683·Phase 2, Phase 3·Recruiting·Listed Aug 2022

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VIBRANT: VIB4920 for Active Lupus Nephritis

for Lupus Nephritis

Sites in Ann Arbor +15 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT05201469·Phase 2·Recruiting·Listed Jan 2022

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Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

for Primary Immune Deficiency

Sites in Ann Arbor +1 more location

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Month - 100

Code: NCT00246857·Recruiting·Listed Oct 2005

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Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction

for ACL

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 14 - 45

Code: NCT06529692·Recruiting·Listed Jul 2024

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Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

for Neoadjuvant Treatment

Sites in Ann Arbor +3 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06959511·Phase 2·Recruiting·Listed May 2025

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Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

for Obstructive Sleep Apnea

Sites in Ann Arbor +5 more locations

Sponsor: Oregon Health and Science University

Sex: All·Age: 2 - 17

Code: NCT05508971·Recruiting·Listed Aug 2022

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A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

for Endogenous Cushing Syndrome

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 75

Code: NCT06430528·Recruiting·Listed May 2024

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Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing

for Hypothyroidism

Sites in Ann Arbor, Detroit +1 more location

Sponsor: University of Michigan

Sex: All·Age: 65+

Code: NCT06629272·Recruiting·Listed Oct 2024

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Lurbinectedin in FET-Fused Tumors

for Ewing Sarcoma

Drug: Lurbinectedin

Sites in Ann Arbor +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10+

Code: NCT05918640·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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Speech Signals in Stuttering

for Stuttering, Childhood

Sites in Ann Arbor +1 more location

Sponsor: University of Pittsburgh

Sex: All·Age: 5 - 17·Accepts healthy volunteers

Code: NCT05668923·Recruiting·Listed Dec 2022

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Addressing Root Causes for Gun Violence Prevention (ARC-GVP)

for Violence

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 14 - 24·Accepts healthy volunteers

Code: NCT05887973·Recruiting·Listed Jun 2023

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Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

for Osteoarthritis, Knee

1 location in Ann Arbor

Sponsor: Steven E Harte, PhD

Sex: All·Age: 21 - 75

Code: NCT04992624·Phase 2·Recruiting·Listed Aug 2021

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The SEQUENCE Trial

for Pulmonary Nodules

Sites in Ann Arbor +4 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06676956·Recruiting·Listed Nov 2024

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Short-term Implanted Electrodes Following Regenerative Peripheral Nerve Surgery for Improving Prosthetic Limb Control Signals

for Amputation Neuroma

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 22 - 75

Code: NCT03260400·Recruiting·Listed Aug 2017

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REVEAL Biomarkers of Engraftment After Alternative Donor HSCT

for Primary Graft Failure

Sites in Ann Arbor +3 more locations

Sponsor: University of Oklahoma

Sex: All·Age: 4 - 80

Code: NCT03541889·Phase 1·Recruiting·Listed May 2018

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EDRN Prostate MRI Biomarker Study

for PSA

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: Male·Age: 18+

Code: NCT03784924·Recruiting·Listed Dec 2018

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Implant Phenotype Modification Via GBR and ADM

for Horizontal Ridge Deficiency

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07082244·Recruiting·Listed Jul 2025

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Feasibility Pilot Sequential Multiple Assignment Randomized Trial (SMART) for Acute Severe Ulcerative Colitis

for Ulcerative Colitis Acute

1 location in Ann Arbor

Sponsor: Berinstein, Jeffrey

Sex: All·Age: 18 - 75

Code: NCT05867329·Phase 4·Recruiting·Listed May 2023

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Deep Functional Phenotyping of the ALA Lung Health Cohort

for Lung Diseases

Sites in Ann Arbor +11 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT06177717·Recruiting·Listed Dec 2023

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Ann Arbor, Detroit +34 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

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Efficacy of a Wearable Noninvasive Neuromodulation Device

for Spinal Cord Injuries

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07171489·Recruiting·Listed Sep 2025

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Ann Arbor +18 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

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Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

Sites in Ann Arbor +23 more locations

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting·Listed Jan 2024

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Ann Arbor, Detroit +14 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy

for Posterior Cortical Atrophy

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50+

Code: NCT07191327·Recruiting·Listed Sep 2025

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Inorganic Nitrate (NaNO3) Prevention of Contrast-Associated Acute Kidney Injury

for Kidney Injury, Acute

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07016074·Phase 2·Recruiting·Listed Jun 2025

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Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

for Post Traumatic Stress Disorder

Sites in Ann Arbor, Detroit +9 more locations

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT05751473·Recruiting·Listed Mar 2023

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Mobile Platform for Optimizing Wellness and Engagement in Recovery

for Opioid Agonist Treatment

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 19 - 63

Code: NCT07178990·Recruiting·Listed Sep 2025

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Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients

for Inflammatory Bowel Diseases

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06188793·Recruiting·Listed Jan 2024

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Improve New Learning and Memory in Individuals With Mild Cognitive Impairment

for Mild Cognitive Impairment

Sites in Ann Arbor +1 more location

Sponsor: Kessler Foundation

Sex: All·Age: 60+

Code: NCT05396248·Recruiting·Listed May 2022

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CTSN Embolic Protection Trial

for Delirium

Sites in Ann Arbor +18 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting·Listed Sep 2023

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A Community Health Worker-Led Program for Chronic Pain and Loneliness in Older Adults

for Chronic Pain

1 location in Ann Arbor

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 60+

Code: NCT06671925·Recruiting·Listed Nov 2024

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Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype

for Multiple Sclerosis

1 location in Ann Arbor

Sponsor: Tiffany J. Braley, MD, MS

Sex: All·Age: 18 - 65

Code: NCT05269628·Phase 2·Recruiting·Listed Mar 2022

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Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

for Chronic Kidney Disease(CKD)

Sites in Ann Arbor +6 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06906627·Recruiting·Listed Apr 2025

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Improving Coping to Reduce Suicide Risk Following ED Discharge

for Suicidal

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 65

Code: NCT06614946·Recruiting·Listed Sep 2024

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Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer

for Breast Cancer

Drug: Ribociclib

Sites in Ann Arbor, Wyoming +1 more location

Sponsor: University of Michigan Rogel Cancer Center

Sex: Female·Age: 18+

Code: NCT05996107·Phase 1·Recruiting·Listed Aug 2023

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Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance

for Obesity

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 15 - 75·Accepts healthy volunteers

Code: NCT02043457·Recruiting·Listed Jan 2014

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Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

for Type 2 Diabetes

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 14 - 18·Accepts healthy volunteers

Code: NCT06007404·Recruiting·Listed Aug 2023

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in Ann Arbor, Ypsilanti +38 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

Apply to this trial