Clinical Trials at Children's Hospital Colorado

As of July 2026, 157 paid clinical trials are recruiting at Children's Hospital Colorado, located at 13123 E 16TH AVE, BOX 030, AURORA, CO 80045-7106, phone (720) 777-6800 in Aurora, Colorado. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

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159 clinical trials at Children's Hospital Colorado

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Post-operative Cesarean Trial of Pain Control

for Post-operative Pain

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: Female·Age: 18 - 50

Code: NCT05131178·Recruiting·Listed Nov 2021

Apply to this trial

Improving Communication and Building a Stronger Medical Home Among Spanish-speaking Families

for Leukemia

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: Up to 22

Code: NCT05425992·Recruiting·Listed Jun 2022

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

Sites in Aurora +113 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

Sites in Aurora, Denver +16 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting·Listed Nov 2024

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Aurora, Denver +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALL

for B-cell Acute Lymphoblastic Leukemia

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 3 Months - 30

Code: NCT06559189·Phase 1·Recruiting·Listed Aug 2024

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A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

for Chronic Pain

Sites in Aurora +6 more locations

Sponsor: Telethon Kids Institute

Sex: All·Age: Up to 16·Accepts healthy volunteers

Code: NCT06354699·Recruiting·Listed Apr 2024

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Neurophysiologic Biomarkers in Rett Syndrome

for Rett Syndrome

Sites in Aurora +5 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: Female·Age: 1 - 18·Accepts healthy volunteers

Code: NCT05932589·Recruiting·Listed Jul 2023

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Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

for Ewing Sarcoma

Drug: Cabozantinib

Sites in Aurora +3 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 5 - 40

Code: NCT06156410·Phase 1·Recruiting·Listed Dec 2023

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Genesis Electrical Impedance Tomography (EIT): A Preliminary Study

for Premature Infant

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 14 Days - 40·Accepts healthy volunteers

Code: NCT03797183·Recruiting·Listed Jan 2019

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The RightCall: Implementing a Sepsis Diagnostic Toolkit to Improve Pediatric Diagnosis in ED Transfer Calls

for Sepsis

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 1 Month+

Code: NCT07051668·Recruiting·Listed Jul 2025

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STXBP1 and SYNGAP1 Related Disorders Natural History Study

for Genetic Disease

Sites in Aurora +4 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT06555965·Recruiting·Listed Aug 2024

Apply to this trial

HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

Sites in Aurora +14 more locations

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting·Listed Nov 2019

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Fetoscopic Endoluminal Tracheal Occlusion

for Congenital Diaphragmatic Hernia

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: Female·Age: 18+

Code: NCT03674372·Recruiting·Listed Sep 2018

Apply to this trial

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth

for Transgenderism

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 13 - 16

Code: NCT04596592·Recruiting·Listed Oct 2020

Apply to this trial

Immune Responses to Gluten

for Celiac Disease

Sites in Aurora +1 more location

Sponsor: Boston Children's Hospital

Sex: All·Age: 2 - 101·Accepts healthy volunteers

Code: NCT05209568·Recruiting·Listed Jan 2022

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Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

for Relapsed/Refractory KMT2A-r Acute Leukemia

Sites in Aurora +10 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 0 - 21

Code: NCT06376162·Phase 1·Recruiting·Listed Apr 2024

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Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry

for Pulmonary Vascular Disease

Sites in Aurora +12 more locations

Sponsor: New York Medical College

Sex: All·Age: 1 Day - 21

Code: NCT02249923·Recruiting·Listed Sep 2014

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Navigating Together for Equitable Asthma Management for Children in Families Who Communicate in Language Other Than English

for Asthma in Children

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 4 - 89

Code: NCT06239844·Recruiting·Listed Feb 2024

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Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

for Type 2 Diabetes Mellitus

Sites in Aurora +1 more location

Sponsor: Petter Bjornstad

Sex: All·Age: 8 - 14·Accepts healthy volunteers

Code: NCT05008276·Recruiting·Listed Aug 2021

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Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent Training

for Behavioral Problem

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 3 - 5·Accepts healthy volunteers

Code: NCT06505980·Recruiting·Listed Jul 2024

Apply to this trial

The Pediatric Spine Foundation

for Chest Wall and Spinal Disorders

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: Up to 17

Code: NCT02540915·Recruiting·Listed Sep 2015

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The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy

for Klinefelter Syndrome

Sites in Aurora +1 more location

Sponsor: University of Colorado, Denver

Sex: All·Age: 6 Weeks - 13 Months

Code: NCT03396562·Recruiting·Listed Jan 2018

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Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY)

for Sex Chromosome Aneuploidy

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 0 Days - 100·Accepts healthy volunteers

Code: NCT06373861·Recruiting·Listed Apr 2024

Apply to this trial

UCD19 CarT in Treatment of Pediatric B-ALL and B-NHL

for B-cell Acute Lymphoblastic Leukemia

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 31 Days - 30

Code: NCT04544592·Phase 1, Phase 2·Recruiting·Listed Sep 2020

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Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

for Tuberous Sclerosis Complex

Sites in Aurora +9 more locations

Sponsor: Darcy Krueger

Sex: All·Age: 1 Day - 6 Months

Code: NCT05104983·Phase 2·Recruiting·Listed Nov 2021

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Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Aurora +51 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

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Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

for Survivors of Childhood Cancer

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 5 - 13

Code: NCT04993859·Recruiting·Listed Aug 2021

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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

Sites in Aurora +58 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting·Listed Aug 2016

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CNS Qualitative Interview

for Central Nervous System Cancer

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: All ages

Code: NCT05219149·Recruiting·Listed Feb 2022

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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

for B-cell Acute Lymphoblastic Leukemia

Sites in Aurora +23 more locations

Sponsor: Pediatric Transplantation & Cellular Therapy Consortium

Sex: All·Age: 1 - 25

Code: NCT03509961·Phase 2·Recruiting·Listed Apr 2018

Apply to this trial

Puberty, Testosterone, and Brain Development

for Gender Identity

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 12 - 20

Code: NCT06670053·Recruiting·Listed Nov 2024

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Mindfulness Application Effects on Mental Health Symptoms in Children With Severe Tinnitus and Misophonia

for Tinnitus

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 10 - 18·Accepts healthy volunteers

Code: NCT06493825·Recruiting·Listed Jul 2024

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Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry

for Turner Syndrome

Sites in Aurora +9 more locations

Sponsor: University of Colorado, Denver

Sex: Female·Age: All ages

Code: NCT05052606·Recruiting·Listed Sep 2021

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One-4-ALL Initiative

for Literacy

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05454969·Recruiting·Listed Jul 2022

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Longitudinal Study of Urea Cycle Disorders

for Brain Diseases, Metabolic, Inborn

Sites in Aurora +11 more locations

Sponsor: Andrea Gropman

Sex: All·Age: All ages

Code: NCT00237315·Recruiting·Listed Oct 2005

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Uric Acid Lowering Trial in Youth Onset T2D

for Diabetic Kidney Disease

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: Male·Age: 18 - 25

Code: NCT03899883·Phase 2·Recruiting·Listed Apr 2019

Apply to this trial