Paid Clinical Trials in Colorado

Colorado has 1,892 paid clinical trials enrolling now across cities including Aurora, Denver and Colorado Springs. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Colorado include University of Colorado Anschutz and National Jewish Health, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Breast Cancer, Colorectal Cancer, Obesity, Advanced Solid Tumor — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 30, 2026.

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Healthy volunteers only

Newly added in Colorado

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

Effects of GLP-1 RAs on Human Lactation Outcomes

for Lactation

1 location in Aurora

Sponsor: University of Colorado, Denver

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT07720414·Recruiting·Listed Jul 22, 2026

Apply to this trial

MoblO2 to Maintain Oxygenation

for COPD (Chronic Obstructive Pulmonary Disease)

1 location in Denver

Sponsor: Minnesota HealthSolutions

Sex: All·Age: 25 - 95

Code: NCT07704567·Recruiting·Listed Jul 15, 2026

Apply to this trial

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

for Advanced or Metastatic Solid Tumors

Sites in Denver +2 more locations

Sponsor: SHY Therapeutics

Sex: All·Age: 18+

Code: NCT07705334·Phase 1·Recruiting·Listed Jul 15, 2026

Apply to this trial

SanaMente: A Peer-Led Program to Reduce Health Disparities in Rural Latino/a Communities

for Depression and/or Anxiety in the Mild-to-moderate Range

1 location in Carbondale

Sponsor: University of Colorado, Boulder

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07705776·Recruiting·Listed Jul 15, 2026

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A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for AML

Sites in Aurora, Denver +24 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07702578·Phase 3·Recruiting·Listed Jul 14, 2026

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A Long-Term Safety Follow-up Registry for Patients Who Received Treatment With Prademagene Zamikeracel for Recessive Dystrophic Epidermolysis Bullosa (RDEB) in the Post-Marketing Setting

for Recessive Dystrophic Epidermolysis Bullosa

Sites in Aurora +3 more locations

Sponsor: Abeona Therapeutics, Inc

Sex: All·Age: All ages

Code: NCT07700966·Recruiting·Listed Jul 14, 2026

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1,664 clinical trials

A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine

for Migraine

Drug: Elismetrep

Sites in Colorado Springs, Fort Collins +112 more locations

Sponsor: Kallyope Inc.

Sex: All·Age: 18 - 75

Code: NCT07645924·Phase 3·Recruiting·Listed Jun 12, 2026

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A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration

for Neovascular Age-related Macular Degeneration

Drug: Aflibercept

Sites in Colorado Springs +35 more locations

Sponsor: Amgen

Sex: All·Age: 50+

Code: NCT07614776·Phase 3·Recruiting·Listed May 2026

Apply to this trial

A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

for Pneumococcal Disease

Sites in Aurora +78 more locations

Sponsor: Pfizer

Sex: All·Age: 42 Days - 211 Days·Accepts healthy volunteers

Code: NCT07629440·Phase 3·Recruiting·Listed Jun 5, 2026

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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

Drug: NNC0487-0111

Sites in Aurora, Denver +204 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Recruiting·Listed May 2026

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A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

for Cognitive Dysfunction

Drug: Donanemab

Sites in Englewood +41 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 55 - 85

Code: NCT07589595·Phase 2·Recruiting·Listed May 2026

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A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for Major Depressive Disorder

Sites in Denver +29 more locations

Sponsor: Definium Therapeutics US, Inc.

Sex: All·Age: 18 - 74

Code: NCT07592689·Phase 3·Recruiting·Listed May 2026

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A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

for Obesity

Drug: Semaglutide

Sites in Aurora +98 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07564414·Phase 3·Recruiting·Listed May 2026

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A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis

Sites in Wheat Ridge +32 more locations

Sponsor: Apollo Therapeutics Ltd

Sex: All·Age: 18 - 65

Code: NCT07599813·Phase 2·Recruiting·Listed May 2026

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A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for Macular Degeneration

Sites in Denver, Colorado Springs +48 more locations

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07496567·Phase 2, Phase 3·Recruiting·Listed Mar 2026

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An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

Drug: Pelacarsen

Sites in Aurora +119 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting·Listed Apr 2026

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A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris

for Lichen Planopilaris

Sites in Denver +46 more locations

Sponsor: Priovant Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07532603·Phase 2, Phase 3·Recruiting·Listed Apr 2026

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Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

for Urothelial Cancer

Drug: PF-08634404

Sites in Aurora, Denver +93 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07421700·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for Solid Tumors

Drug: INCB161734

Sites in Denver +67 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07522073·Phase 3·Recruiting·Listed Apr 2026

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A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

Drug: Risankizumab

Sites in Colorado Springs +23 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07499232·Phase 3·Recruiting·Listed Mar 2026

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COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

for Diabetic Macular Edema

Drug: Aflibercept

Sites in Colorado Springs, Lakewood +48 more locations

Sponsor: EyePoint Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07449936·Phase 3·Recruiting·Listed Mar 2026

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CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

for Diabetic Macular Edema

Drug: Aflibercept

Sites in Arvada +49 more locations

Sponsor: EyePoint Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07449923·Phase 3·Recruiting·Listed Mar 2026

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Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma

Drug: PF-08634404

Sites in Aurora, Denver +57 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07392892·Phase 2, Phase 3·Recruiting·Listed Feb 2026

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An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

for Post Traumatic Stress Disorder

Drug: TSND-201

Sites in Evergreen +31 more locations

Sponsor: Transcend Therapeutics

Sex: All·Age: 18+

Code: NCT07456696·Phase 3·Recruiting·Listed Mar 2026

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Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

for HIV Infections

Sites in Denver +30 more locations

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT07473778·Recruiting·Listed Mar 2026

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LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis (UC)

Drug: LY4268989

Sites in Colorado Springs, Lakewood +48 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07415044·Phase 2·Recruiting·Listed Feb 2026

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Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)

for Neovascular Age-Related Macular Degeneration (nAMD)

Drug: Ixo-vec

Sites in Denver +78 more locations

Sponsor: Adverum Biotechnologies, Inc.

Sex: All·Age: 50+

Code: NCT07482176·Phase 3·Recruiting·Listed Mar 2026

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Phase 2 Study to Assess the Safety and Efficacy of ANG003

for Exocrine Pancreatic Insufficiency (EPI)

Sites in Denver +25 more locations

Sponsor: Anagram Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07450547·Phase 2·Recruiting·Listed Mar 2026

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A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for Parkinson Disease

Sites in Englewood +29 more locations

Sponsor: Appello Pharmaceuticals, Inc.

Sex: All·Age: 30 - 80

Code: NCT07432958·Phase 2·Recruiting·Listed Feb 2026

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Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease

for Primary Sjogren's Disease

Drug: Telitacicept

Sites in Denver +27 more locations

Sponsor: Vor Biopharma

Sex: All·Age: 18 - 75

Code: NCT07404865·Phase 3·Recruiting·Listed Feb 2026

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A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

for Chronic Idiopathic Constipation (CIC)

Drug: Tenapanor

Sites in Denver, Lakewood +107 more locations

Sponsor: Ardelyx

Sex: All·Age: 18 - 80

Code: NCT07382167·Phase 3·Recruiting·Listed Feb 2026

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A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

for Systemic Lupus Erythematosus

Drug: BI 3000202

Sites in Denver +29 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 74

Code: NCT07409181·Phase 2·Recruiting·Listed Feb 2026

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A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

for Uncontrolled Gout

Sites in Denver +55 more locations

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07388498·Phase 3·Recruiting·Listed Feb 2026

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A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

Sites in Golden +36 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting·Listed Jan 2026

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Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

for Osteoarthritis

Drug: Eloralintide

Sites in Colorado Springs +37 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07353931·Phase 3·Recruiting·Listed Jan 2026

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A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

Sites in Aurora +31 more locations

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting·Listed Feb 2026

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PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

for Proteinuric Kidney Diseases

Sites in Denver +24 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT07355296·Phase 2·Recruiting·Listed Jan 2026

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A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

Sites in Lakewood +40 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting·Listed Jan 2026

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A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

for Liver Cirrhosis

Drug: BI 3802876

Sites in Colorado Springs +25 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 75

Code: NCT07325526·Phase 2·Recruiting·Listed Jan 2026

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A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

for Overweight

Drug: Eloralintide

Sites in Aurora +59 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07282600·Phase 3·Recruiting·Listed Dec 2025

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A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

for CRC (Colorectal Cancer)

Drug: Bevacizumab

Sites in Aurora +69 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07284849·Phase 3·Recruiting·Listed Dec 2025

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A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

for Breast Neoplasms

Sites in Loveland, Greeley +26 more locations

Sponsor: Eli Lilly and Company

Sex: Female·Age: 18+

Code: NCT07287098·Phase 2·Recruiting·Listed Dec 2025

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Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for Carcinoma, Renal Cell

Drug: PF-08634404

Sites in Denver +108 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07227415·Phase 1, Phase 2·Recruiting·Listed Nov 2025

Apply to this trial

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for Intestinal Neoplasms

Drug: PF-08634404

Sites in Aurora, Denver +179 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07222800·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

Sites in Boulder, Wheat Ridge +68 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT07231419·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Aurora, Denver +27 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

Common conditions studied in Colorado

Breast Cancer (34 active studies)
Colorectal Cancer (23 active studies)
Obesity (23 active studies)
Advanced Solid Tumor (21 active studies)
Heart Failure (21 active studies)
Multiple Myeloma (21 active studies)

Leading research sponsors in Colorado

University of Colorado, Denver
National Cancer Institute (NCI)
AstraZeneca
Merck Sharp & Dohme LLC
Eli Lilly and Company

Frequently asked questions

How many paid clinical trials are currently recruiting in Colorado?

There are approximately 1,892 recruiting clinical trials in Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Colorado pay participants?

Most recruiting trials in Colorado compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Colorado?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Colorado?

The most common conditions under active study in Colorado include Breast Cancer (34), Colorectal Cancer (23), Obesity (23), Advanced Solid Tumor (21), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Colorado?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Colorado on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Colorado?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Browse more clinical trials

All cities in Colorado

Aurora, CO(1,052)Denver, CO(524)Colorado Springs, CO(191)Englewood, CO(88)Lone Tree, CO(88)Fort Collins, CO(81)Lakewood, CO(80)Boulder, CO(65)Littleton, CO(57)Loveland, CO(57)Greeley, CO(48)Longmont, CO(47)Grand Junction, CO(42)Pueblo, CO(37)Highlands Ranch, CO(36)Centennial, CO(35)Golden, CO(32)Westminster, CO(32)Durango, CO(30)Thornton, CO(28)Wheat Ridge, CO(24)Lafayette, CO(22)Edwards, CO(16)Parker, CO(14)Greenwood Village, CO(12)Arvada, CO(10)Castle Rock, CO(9)Broomfield, CO(8)Dillon, CO(5)Brighton, CO(4)Evergreen, CO(4)Vail, CO(4)Basalt, CO(2)Glenwood Springs, CO(2)Greenwood, CO(2)Sheridan, CO(2)Steamboat Springs, CO(2)Air Force Academy, CO(1)Ault, CO(1)Carbondale, CO(1)Cheyenne Wells, CO(1)Craig, CO(1)Cripple Creek, CO(1)Ellicott, CO(1)Estes Park, CO(1)Falcon, CO(1)Firestone, CO(1)Fort Lupton, CO(1)Fountain, CO(1)Fruita, CO(1)Granada, CO(1)Gunnison, CO(1)La Junta, CO(1)Lamar, CO(1)Las Animas, CO(1)Louisville, CO(1)Manzanola, CO(1)Montrose, CO(1)Monument, CO(1)Multiple Locations, CO(1)Platteville, CO(1)Sterling, CO(1)Timnath, CO(1)West Vail, CO(1)Wiggins, CO(1)Windsor, CO(1)Woodland Park, CO(1)

Related healthcare resources in Colorado

Behavioral health news in Colorado Latest Colorado clinical trials research report

Trials by condition in Colorado

Breast Cancer· 34 Colorectal Cancer· 23 Obesity· 23 Heart Failure· 21 Multiple Myeloma· 21 Ovarian Cancer· 20