Clinical Trials at Johns Hopkins Hospital

As of September 2026, 118 paid clinical trials are recruiting at Johns Hopkins Hospital, located at JOHNS HOPKINS DEPARTMENT OF SURGERY, 600 N WOLFE ST TOWER 110, BALTIMORE, MD 21287-0001, phone (410) 955-5020 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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121 clinical trials at Johns Hopkins Hospital

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Proton SBRT for Spinal Metastasis

for Spinal Metastasis

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06895564·Recruiting·Listed Mar 2025

Apply to this trial

Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

for Basal Cell Carcinoma

Drug: Ipilimumab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT03521830·Phase 2·Recruiting·Listed May 2018

Apply to this trial

Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe

for Prostate Cancer (Diagnosis)

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Male·Age: 40 - 75

Code: NCT07271017·Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

for Acute Kidney Injury

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06840210·Recruiting·Listed Feb 2025

Apply to this trial

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).

for NF1

Drug: Mirdametinib

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06159166·Phase 1, Phase 2·Recruiting·Listed Dec 2023

Apply to this trial

320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial Fibrillation Before AF Ablation.

for Atrial Fibrillation

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06308094·Recruiting·Listed Mar 2024

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Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

for Endometriosis

Sites in Baltimore +1 more location

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06847685·Recruiting·Listed Feb 2025

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Home Intravenous Fluid Infusion After Undergoing Radical Cystectomy

for Bladder Cancer

2 locations in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07225205·Recruiting·Listed Nov 2025

Apply to this trial

Cerebellar Stimulation for Aphasia Rehabilitation

for Stroke

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 99

Code: NCT05093673·Recruiting·Listed Oct 2021

Apply to this trial

Exercise Intolerance in Heart Failure

for Heart Failure With Normal Ejection Fraction

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT03775577·Recruiting·Listed Dec 2018

Apply to this trial

Community Health Worker-Led Intervention to Increase Cardiac Rehabilitation Participation

for CVD - Cardiovascular Disease

3 locations in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06908590·Recruiting·Listed Apr 2025

Apply to this trial

Study of Healthy Cohort for Early Detection of Cancer

for Healthy

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05193305·Recruiting·Listed Jan 2022

Apply to this trial

Investigating Dyadic Expectations About ARF Survivorship (IDEAS)

for Acute Respiratory Failure

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06401239·Recruiting·Listed May 2024

Apply to this trial

Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

for Sarcoma

Drug: Nivolumab

Sites in Baltimore +2 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 12 Months - 40

Code: NCT03465592·Phase 1, Phase 2·Recruiting·Listed Mar 2018

Apply to this trial

Yoga for Back Pain in Adolescent Scoliosis

for Scoliosis Idiopathic Adolescent Treatment

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 10 - 20

Code: NCT06242821·Recruiting·Listed Feb 2024

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Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure

for Heart Failure With Reduced Ejection Fraction

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT06299436·Recruiting·Listed Mar 2024

Apply to this trial

Pediatric Radiation Therapy Registry

for Sarcoma

Sites in Baltimore +1 more location

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 0 - 26

Code: NCT07129317·Recruiting·Listed Aug 2025

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Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics

for Sleep Apnea, Obstructive

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05429983·Recruiting·Listed Jun 2022

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Full-Field Optical Coherence Tomography (FFOCT) for Evaluation of Bronchoscopic Small Biopsy Specimens

for Lung Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05171478·Recruiting·Listed Dec 2021

Apply to this trial

Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration

for Diabetic Foot Ulcer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT04164641·Recruiting·Listed Nov 2019

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EsophaCap for the Detection of Early Esophageal Carcinoma

for Barrett Esophagus

2 locations in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04214119·Recruiting·Listed Jan 2020

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Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)

for Fibroid

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 55

Code: NCT06135870·Recruiting·Listed Nov 2023

Apply to this trial

Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis

for Post-ERCP Acute Pancreatitis

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05252754·Phase 3·Recruiting·Listed Feb 2022

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The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

for Kidney Neoplasm

1 location in Baltimore

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT02346435·Recruiting·Listed Jan 2015

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Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

for Bladder Cancer

Sites in Baltimore +1 more location

Sponsor: Johns Hopkins University

Sex: Male·Age: 18+

Code: NCT05792722·Recruiting·Listed Mar 2023

Apply to this trial

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

for HIV Infections

Sites in Baltimore & Frederick

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06103370·Recruiting·Listed Oct 2023

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Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

for Chordoma of Spine

Sites in Baltimore +1 more location

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06463262·Recruiting·Listed Jun 2024

Apply to this trial

Personalized Treatment in Thyroid Disorders

for Thyroid Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65

Code: NCT03517579·Recruiting·Listed May 2018

Apply to this trial

The Cancer of the Pancreas Screening-5 CAPS5)Study

for Pancreas Cancer

Sites in Baltimore +8 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT02000089·Phase 3·Recruiting·Listed Dec 2013

Apply to this trial

Gender Related Coping and Survivorship for Genitourinary Cancers

for Bladder Cancer

Sites in Baltimore +1 more location

Sponsor: Johns Hopkins University

Sex: Female·Age: 18+

Code: NCT05649306·Recruiting·Listed Dec 2022

Apply to this trial

American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

for Pancreatic Cancer

Sites in Baltimore +10 more locations

Sponsor: University of Louisville

Sex: All·Age: 18+

Code: NCT02674100·Recruiting·Listed Feb 2016

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Multicenter Trial Evaluating the Safety and Efficacy of Autologous Volar Fibroblast Injection Into the Terminal Limb of Amputees.

for Amputation

1 location in Baltimore

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 75

Code: NCT04839497·Phase 2·Recruiting·Listed Apr 2021

Apply to this trial

POEM-F for Achalasia International Study

for Achalasia

1 location in Baltimore

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18 - 65

Code: NCT06042127·Recruiting·Listed Sep 2023

Apply to this trial

Transventricular Off-pump Mitral Valve Repair

for Mitral Valve (MV) Regurgitation

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT07726173·Recruiting·Listed Jul 2026

Apply to this trial

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

for Systemic Sclerosis

Drug: Nerandomilast

Sites in Baltimore +29 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07497087·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

for Solid Tumors

Sites in Baltimore +15 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07492680·Phase 2·Recruiting·Listed Mar 2026

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A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)

for Fibrosing Interstitial Lung Disease

Drug: Nerandomilast

Sites in Baltimore +6 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07366034·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors

for Periampullary Neoplasms

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT07360119·Recruiting·Listed Jan 2026

Apply to this trial