Clinical Trials at Johns Hopkins Hospital

As of July 2026, 124 paid clinical trials are recruiting at Johns Hopkins Hospital, located at JOHNS HOPKINS DEPARTMENT OF SURGERY, 600 N WOLFE ST TOWER 110, BALTIMORE, MD 21287-0001, phone (410) 955-5020 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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124 clinical trials at Johns Hopkins Hospital

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Safety of Erythropoietin and Melatonin for Very Preterm Infants With Intraventricular Hemorrhage

for Intraventricular Hemorrhage of Prematurity

2 locations incl. St. Petersburg

Sponsor: Johns Hopkins University

Sex: All·Age: 12 Hours - 2 Months

Code: NCT05617833·Phase 1·Recruiting

Apply to this trial

Investigating Dyadic Expectations About ARF Survivorship (IDEAS)

for Acute Respiratory Failure

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06401239·Recruiting

Apply to this trial

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

for Primary Progressive Aphasia

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT05386394·Phase 2·Recruiting

Apply to this trial

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).

for NF1

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06159166·Phase 1, Phase 2·Recruiting

Apply to this trial

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]

for Coronary Artery Disease

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05994014·Recruiting

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Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

for Brain Tumor

2 locations incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 1 - 26·Accepts healthy volunteers

Code: NCT05658731·Recruiting

Apply to this trial

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

for AMCI - Amnestic Mild Cognitive Impairment

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 55+

Code: NCT05282550·Phase 2·Recruiting

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Proton Radiation Therapy Registry

for Cancer, Therapy-Related

4 locations incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18 - 100

Code: NCT04376229·Recruiting

Apply to this trial

Skeletal Muscle Energetics and Fatiguability in Older Individuals

for HIV

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 60 - 90·Accepts healthy volunteers

Code: NCT04142047·Recruiting

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Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy

for Cerebral Palsy

4 locations incl. Baltimore

Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT05197946·Recruiting

Apply to this trial

Ketogenic Diet for New-Onset Absence Epilepsy

for Absence Epilepsy

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 3 - 12

Code: NCT04274179·Phase 3·Recruiting

Apply to this trial

The Impact of COVID-19 on Maternal and Neonatal Outcomes

for COVID-19

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 14 - 55·Accepts healthy volunteers

Code: NCT05197621·Recruiting

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Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

for Basal Cell Carcinoma

Drug: Ipilimumab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT03521830·Phase 2·Recruiting

Apply to this trial

Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

for Chordoma of Spine

2 locations incl. Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06463262·Recruiting

Apply to this trial

Cerebellar Stimulation for Aphasia Rehabilitation

for Stroke

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 99

Code: NCT05093673·Recruiting

Apply to this trial

Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)

for Systemic Lupus Erythematosus

8 locations incl. Chicago

Sponsor: Hospital for Special Surgery, New York

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT00198068·Recruiting

Apply to this trial

Exercise Intolerance in Heart Failure

for Heart Failure With Normal Ejection Fraction

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT03775577·Recruiting

Apply to this trial

Study of Healthy Cohort for Early Detection of Cancer

for Healthy

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05193305·Recruiting

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Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)

for Fibroid

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 55

Code: NCT06135870·Recruiting

Apply to this trial

Transrectal Ultrasound Robot-Assisted Prostate Biopsy

for Prostate Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Male·Age: 45 - 75

Code: NCT02871726·Recruiting

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Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

for Sarcoma

Drug: Nivolumab

4 locations incl. St. Petersburg

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 12 Months - 40

Code: NCT03465592·Phase 1, Phase 2·Recruiting

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Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

for Bladder Cancer

2 locations incl. Washington D.C.

Sponsor: Johns Hopkins University

Sex: Male·Age: 18+

Code: NCT05792722·Recruiting

Apply to this trial

Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis

for Post-ERCP Acute Pancreatitis

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05252754·Phase 3·Recruiting

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Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics

for Sleep Apnea, Obstructive

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05429983·Recruiting

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Full-Field Optical Coherence Tomography (FFOCT) for Evaluation of Bronchoscopic Small Biopsy Specimens

for Lung Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05171478·Recruiting

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Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration

for Diabetic Foot Ulcer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT04164641·Recruiting

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Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

for Pleural Effusion

5 locations incl. Arlington Heights

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT03831386·Recruiting

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EsophaCap for the Detection of Early Esophageal Carcinoma

for Barrett Esophagus

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04214119·Recruiting

Apply to this trial

Gender Related Coping and Survivorship for Genitourinary Cancers

for Bladder Cancer

2 locations incl. Washington D.C.

Sponsor: Johns Hopkins University

Sex: Female·Age: 18+

Code: NCT05649306·Recruiting

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Multicenter Trial Evaluating the Safety and Efficacy of Autologous Volar Fibroblast Injection Into the Terminal Limb of Amputees.

for Amputation

1 location in Baltimore

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 75

Code: NCT04839497·Phase 2·Recruiting

Apply to this trial

The Cancer of the Pancreas Screening-5 CAPS5)Study

for Pancreas Cancer

9 locations incl. New Haven

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT02000089·Phase 3·Recruiting

Apply to this trial

Personalized Treatment in Thyroid Disorders

for Thyroid Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65

Code: NCT03517579·Recruiting

Apply to this trial

Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

for Logopenic Progressive Aphasia

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT03887481·Recruiting

Apply to this trial

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

for Ischemic Stroke

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05556395·Recruiting

Apply to this trial

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

for Kidney Neoplasm

1 location in Baltimore

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT02346435·Recruiting

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Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

for Pancreatic Cancer

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT05141513·Phase 1·Recruiting

Apply to this trial

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

for Barrett's Esophagus

10 locations incl. Baltimore

Sponsor: Case Western Reserve University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00288119·Recruiting

Apply to this trial

Pancreatic Cancer Registry: For Any Person With a Personal or Family History

for Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT02886247·Recruiting

Apply to this trial

Effects of Simvastatin on Uterine Leiomyoma Size

for Fibroid Uterus

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 55

Code: NCT03400826·Phase 2·Recruiting

Apply to this trial

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

for Child

11 locations incl. Madera

Sponsor: Johns Hopkins University

Sex: All·Age: Up to 18

Code: NCT04989790·Recruiting

Apply to this trial