Clinical Trials at Johns Hopkins University/Sidney Kimmel Cancer Center

As of July 2026, 73 paid clinical trials are recruiting at Johns Hopkins University/Sidney Kimmel Cancer Center, located at Sidney Kimmel Comprehensive Cancer Center, 401 N Broadway, Baltimore, MD 21231, phone (410) 955-5222 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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73 clinical trials at Johns Hopkins University/Sidney Kimmel Cancer Center

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

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Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

for Recurrent B Acute Lymphoblastic Leukemia

156 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 21

Code: NCT02981628·Phase 2·Recruiting

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

112 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

106 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

156 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

101 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting

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A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

for Malignant Glioma

Drug: Selinexor

109 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 Months - 21

Code: NCT05099003·Phase 1, Phase 2·Recruiting

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A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

76 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

58 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for Anatomic Stage IV Breast Cancer AJCC v8

58 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500481·Phase 3·Recruiting

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Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

43 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06287775·Phase 1, Phase 2·Recruiting

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

69 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting

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CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

for Diffuse Midline Glioma, H3 K27-Altered

34 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 21

Code: NCT04870944·Phase 1, Phase 2·Recruiting

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Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for Lymphoid Leukemia

22 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: Up to 26

Code: NCT05865301·Recruiting

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Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

for Metastatic Colorectal Adenocarcinoma

Drug: Cemiplimab

5 locations incl. Atlanta

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07147231·Phase 1, Phase 2·Recruiting

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

29 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

22 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting

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Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

for Castration Resistant Metastatic Prostate Cancer

6 locations incl. San Diego

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Male·Age: 18 - 90

Code: NCT04363164·Phase 2·Recruiting

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Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

for Recurrent Mantle Cell Lymphoma

Drug: Glofitamab

9 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07003295·Phase 2·Recruiting

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Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

for Human Papillomavirus-Related Carcinoma

4 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05985681·Phase 1·Recruiting

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Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for Clinical Stage III Cutaneous Melanoma AJCC v8

26 locations incl. La Jolla

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05896839·Phase 1, Phase 2·Recruiting

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Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

for Metastatic Dedifferentiated Liposarcoma

Drug: Peposertib

16 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05711615·Phase 1·Recruiting

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Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

for Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation

13 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT05691465·Phase 2·Recruiting

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

10 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting

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A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

for Plasmablastic Lymphoma

Drug: Daratumumab

8 locations incl. Miami

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT04139304·EARLY_Phase 1·Recruiting

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Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers

for Malignant Female Reproductive System Neoplasm

2 locations incl. Baltimore

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03968406·Phase 1·Recruiting

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Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

for Acute Myeloid Leukemia

3 locations incl. Baltimore

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 12+

Code: NCT03383575·Phase 2·Recruiting

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Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Newly Diagnosed, Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

for Desmoplastic Small Round Cell Tumor

28 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 39

Code: NCT04616560·Phase 1, Phase 2·Recruiting

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