Oncology Clinical Trials in Bethesda, MD

As of July 2026, 186 paid clinical trials are recruiting for Oncology in Bethesda, Maryland. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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187 clinical trials for Oncology

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Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

for Multiple Myeloma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT02682667·Recruiting·Listed Feb 2016

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Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS

for Myelodysplastic Syndromes

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 Day - 120·Accepts healthy volunteers

Code: NCT05350748·Recruiting·Listed Apr 2022

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Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

for Malignant Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00026884·Recruiting·Listed Nov 2001

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Psychological Benefits of a Normalized Camping Experience for Children With Cancer

for Pediatric Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 7 - 25

Code: NCT00001186·Recruiting·Listed Nov 1999

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Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal Cancer

for Non-GI Cancers

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT01313442·Recruiting·Listed Mar 2011

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En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device

for Bladder Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT04235764·Recruiting·Listed Jan 2020

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Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors

for Advanced Malignant Solid Neoplasm

Drug: Peposertib

Sites in Bethesda +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687136·Phase 1·Recruiting·Listed Jan 2023

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Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

for Peritoneal Mesothelioma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT04847063·Phase 1·Recruiting·Listed Apr 2021

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Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

for Malignant Solid Neoplasm

Sites in Bethesda +3 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03750227·Phase 3·Recruiting·Listed Nov 2018

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Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

for Kidney Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00033137·Recruiting·Listed Apr 2002

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A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors

for Neuroendocrine Carcinomas

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06041516·Phase 1·Recruiting·Listed Sep 2023

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Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue

for Prostate Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT02594202·Recruiting·Listed Nov 2015

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Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

for Lymphoma

Drug: Venetoclax

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03223610·Phase 1, Phase 2·Recruiting·Listed Jul 2017

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Studies on Tumors of the Thyroid

for Hurthle Cell Thyroid Cancer

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 6 Months - 98

Code: NCT00001160·Recruiting·Listed Nov 1999

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Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

for Malignant Solid Tumors

Sites in Bethesda +2 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 Weeks+·Accepts healthy volunteers

Code: NCT03739827·Recruiting·Listed Nov 2018

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A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

for Locally Advanced Alveolar Soft Part Sarcoma

Drug: Atezolizumab

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06066138·Phase 1·Recruiting·Listed Oct 2023

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Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

for Epstein-Barr Virus Infections

Drug: Nivolumab

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT03258567·Phase 2·Recruiting·Listed Aug 2017

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Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

for Neuroblastoma

Drug: Irinotecan

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3 - 35

Code: NCT06995872·Phase 1·Recruiting·Listed May 2025

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Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer

for Prostate Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT04808427·Recruiting·Listed Mar 2021

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A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

for Melanoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 72

Code: NCT02621021·Phase 2·Recruiting·Listed Dec 2015

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Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

for Waldenstrom Macroglobulinemia

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 110

Code: NCT00923507·Recruiting·Listed Jun 2009

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Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

for HER2-negative Breast Cancer

Sites in Bethesda +2 more locations

Sponsor: The Methodist Hospital Research Institute

Sex: All·Age: 18+

Code: NCT05660083·Phase 2·Recruiting·Listed Dec 2022

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T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

for Advanced Non-Small Cell Lung Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 72

Code: NCT02133196·Phase 2·Recruiting·Listed May 2014

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Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

for Urothelial Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT04235777·Phase 1·Recruiting·Listed Jan 2020

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Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

for Hearing Loss

Sites in Bethesda, Baltimore +3 more locations

Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD)

Sex: All·Age: 18 - 100

Code: NCT04915183·Phase 2·Recruiting·Listed Jun 2021

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Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

for Chronic Lymphocytic Leukemia (CLL)

Drug: Venetoclax

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 110

Code: NCT05724121·Recruiting·Listed Feb 2023

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5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03366116·Phase 1·Recruiting·Listed Dec 2017

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Rare Tumors and Cancer Predisposition in Individuals and Families

for Cancer

Sites in Bethesda & Rockville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05350761·Recruiting·Listed Apr 2022

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Collection of Blood From Patients With Prostate Cancer

for Cancer Of Prostate

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT00923221·Recruiting·Listed Jun 2009

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in Bethesda, Elkton +178 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

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Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

for Gastric Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 6+

Code: NCT04557969·Recruiting·Listed Sep 2020

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Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

for Leukemia

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT06856226·Recruiting·Listed Mar 2025

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Sample Collection and Tracking for the Developmental Therapeutics Clinic

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03269578·Recruiting·Listed Sep 2017

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Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

for Metastatic Melanoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT05155033·Phase 2·Recruiting·Listed Dec 2021

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Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

for Sarcoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 Weeks+·Accepts healthy volunteers

Code: NCT01109394·Recruiting·Listed Apr 2010

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Tumor Related Epilepsy

for Epilepsy

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 8 - 99

Code: NCT02639325·Recruiting·Listed Dec 2015

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Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

for Prostate Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00451022·Recruiting·Listed Mar 2007

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Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT04449549·Phase 2·Recruiting·Listed Jun 2020

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18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

for Sarcoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06503146·Phase 2·Recruiting·Listed Jul 2024

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Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

for Kidney Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00001238·Recruiting·Listed Nov 1999

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Conditions in Oncology (Bethesda, MD)

Solid tumor· 28 Cancer (any)· 27 Prostate cancer· 25 Breast cancer· 21 Non-Hodgkin lymphoma· 21 Hematologic malignancy· 14 Melanoma· 13 Non-small cell lung cancer (NSCLC)· 11 Multiple myeloma· 11 Ovarian cancer· 10 Acute myeloid leukemia (AML)· 9 Myelodysplastic syndromes (MDS)· 9 Colorectal cancer· 8 Bladder cancer· 8 Chronic lymphocytic leukemia (CLL)· 8 Acute lymphoblastic leukemia· 8 Leukemia (other)· 8 Neuroendocrine tumors· 8 Lung cancer· 7 Kidney cancer· 7 Diffuse large B-cell lymphoma (DLBCL)· 7 Glioblastoma· 6 Small lymphocytic lymphoma· 6 Pancreatic cancer· 5 Liver cancer· 5 Biliary tract cancer· 5 Gastrointestinal cancer· 5 Neuroblastoma· 5 Mesothelioma· 5 Metastatic breast cancer· 4 Colon cancer· 4 Sarcoma· 4 Gastric cancer· 3 Glioma· 3 Brain cancer· 3 Follicular lymphoma· 3 Mantle cell lymphoma· 3 Thyroid cancer· 3 Metastatic colorectal cancer· 2 Endometrial cancer· 2 Cervical cancer· 2 Myelofibrosis· 2 Myeloproliferative neoplasm· 2 Hodgkin lymphoma· 2 Marginal zone lymphoma· 2 Burkitt lymphoma· 2 Head and neck cancer· 2 Osteosarcoma· 2 HER2-negative breast cancer· 1 Small cell lung cancer· 1 Rectal cancer· 1 Esophageal cancer· 1 Gastroesophageal junction cancer· 1 Metastatic prostate cancer· 1 Uterine cancer· 1 Brain metastases· 1 Skin cancer· 1 Rhabdomyosarcoma· 1 Pediatric cancer· 1