Paid Clinical Trials in Bethesda, MD
As of September 2026, 892 paid clinical trials are recruiting in Bethesda, Maryland. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Bethesda offers studies at sites including National Institutes of Health Clinical Center for conditions such as Healthy Volunteers, Breast Cancer, Prostate Cancer, Healthy Volunteer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Bethesda
Trials by drug in Bethesda
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Newly added in Bethesda
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
794 clinical trials
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
GEMINI-NSCLC: NSCLC Biomarker Study
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis
A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
MEASuRE: Metreleptin Effectiveness And Safety Registry
Top Research Study Locations in Bethesda
Researchers run research studies in Bethesda, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| National Institutes of Health Clinical Center | Healthy Volunteers, Healthy Volunteer, Prostate Cancer | 654 |
| Walter Reed National Military Medical Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Amputation | 68 |
| National Cancer Institute Developmental Therapeutics Clinic | Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm | 11 |
| National Institutes of Health | Abdominal Neoplasm, Advanced Solid Tumors, Anaplastic Astrocytoma | 7 |
| Mid-Atlantic Epilepsy and Sleep Center | Focal Epilepsy, Epilepsy, Focal Onset Seizures | 6 |
| NIH Clinical Center | Age-Related Macular Degeneration, COVID-19, Long Haul, Chronic Granulomatous Disease | 5 |
| National Institute of Health | Cervical Cancer, Chronic Lymphocytic Leukemia (CLL), Diffuse Large B Cell Lymphoma (DLBCL) | 5 |
| The Center for Cancer and Blood Disorders | Acute Myeloid Leukaemia (AML), Advanced Melanoma, Colorectal Cancer | 5 |
| Uniformed Services University of the Health Sciences | Alcohol Use, Arrythmia, Cardiovascular Diseases | 5 |
| National Cancer Institute | Advanced Solid Tumor, Advanced or Metastatic Solid Tumor Malignancies, Cutaneous Squamous Cell Carcinoma | 4 |
| National Cancer Institute (NCI) | Melanoma, Breast Cancer, Cardiofaciocutaneous Syndrome | 4 |
| Center for Cancer and Blood Disorders | Leukemia, Myeloid, Acute, Multiple Myeloma, Sickle Cell Disease | 4 |
| American Oncology Partners of Maryland, PA | Chronic Lymphocytic Leukemia, Immune Thrombocytopenic Purpura (ITP), Leukemia, B-cell | 3 |
| American Oncology Partners, PA | Breast Neoplasms, Chronic Lymphocytic Leukemia, Multiple Myeloma Refractory | 3 |
| American Oncology Partners, PA dba The Center for Cancer and Blood Disorders | Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis, Relapsed/Refractory Multiple Myeloma (RRMM), Secondary Immune Deficiency | 3 |
| Maryland Oncology Hematology, P.A. | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 3 |
| National Institutes of Health (NIH) | Eosinophilic Colitis, Eosinophilic Esophagitis, Eosinophilic Gastritis | 3 |
| Suburban Hospital | Biochemically Recurrent Prostate Carcinoma, Malignant Neoplasm, Metastatic Prostate Carcinoma | 3 |
| American Oncology Partners of Maryland Pa | Chronic Lymphocytic Leukemia, B-cell Malignancy, CLL | 2 |
| GSK Investigational Site | Colonic Neoplasms, Multiple Myeloma, Neoplasms, Colon | 2 |
| Mid Atlantic Epilepsy and Sleep Ctr | Generalized Myasthenia Gravis, Secondary Progressive Multiple Sclerosis (SPMS) | 2 |
| NCI - Center for Cancer Research | Hairy Cell Leukemia, Hereditary Leiomyomatosis and Renal Cell Carcinoma, Papillary Renal Cell Carcinoma | 2 |
| NIH Clinical Site | Drug Induced Liver Injury, Liver Diseases | 2 |
| National Eye Institute (NEI) | Albinism, Aniridia, Best Disease | 2 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Healthy Volunteer Samples, Staphylococcal Infections | 2 |
Active & Upcoming Studies in Bethesda (2026)
Recruiting trials in Bethesda grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (236 active studies)
- A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph... · National Cancer Institute (NCI)
- A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity · Phase 2 · National Cancer Institute (NCI)
Neurology & pain (60 active studies)
- Noninvasive Neuromodulation Of The Subjective Value Network In Chronic Pain · Phase 1 · National Institute of Neurological Disorders and Stroke (NINDS)
- Longitudinal Natural History Protocol for PRKN- and PINK1-Linked PD · National Institute of Neurological Disorders and Stroke (NINDS)
Diabetes & metabolic (25 active studies)
- Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Effects of Meal Macronutrients on Postprandial Lipids · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Mental health & behavior (20 active studies)
- Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum · National Institute of Mental Health (NIMH)
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) · National Institute on Deafness and Other Communication Disorders (NIDCD)
Cardiovascular (19 active studies)
- NHLBI-Emory Advanced Cardiac CT Reconstruction · National Heart, Lung, and Blood Institute (NHLBI)
- Pulmonary Hypertension (PH) Biorepository for Translational Research · National Institutes of Health Clinical Center (CC)
Vaccines (18 active studies)
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) · National Institute on Deafness and Other Communication Disorders (NIDCD)
- BPL-1357 Against H1N1 Influenza Virus Challenge · Phase 2 · National Institute of Allergy and Infectious Diseases (NIAID)
HIV / STI (17 active studies)
- Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ART · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pediatric (10 active studies)
- NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors · National Cancer Institute (NCI)
- A Repository to Study Host-Microbiome Interactions in Health and Disease · National Institute of Allergy and Infectious Diseases (NIAID)
Eye & vision (5 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4 · National Eye Institute (NEI)
Common conditions studied in Bethesda
- Healthy Volunteers (25 active studies)
- Breast Cancer (19 active studies)
- Prostate Cancer (19 active studies)
- Healthy Volunteer (17 active studies)
- Obesity (15 active studies)
- Neoplasms (13 active studies)
Leading research sponsors in Bethesda
- National Cancer Institute (NCI)
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute of Neurological Disorders and Stroke (NINDS)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Frequently asked questions
How many paid clinical trials are currently recruiting in Bethesda?
There are approximately 892 recruiting clinical trials in Bethesda, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Bethesda pay participants?
Most recruiting trials in Bethesda compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Bethesda?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Bethesda?
The most common conditions under active study in Bethesda include Healthy Volunteers (25), Breast Cancer (19), Prostate Cancer (19), Healthy Volunteer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Bethesda?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Bethesda on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Bethesda?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Bethesda?
Recruiting research sites in Bethesda include National Institutes of Health Clinical Center, Walter Reed National Military Medical Center, National Cancer Institute Developmental Therapeutics Clinic, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Bethesda right now?
The largest active categories in Bethesda are Cancer & tumors (236), Neurology & pain (60), Diabetes & metabolic (25). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.