Clinical Trials at National Institutes of Health Clinical Center

As of July 2026, 593 paid clinical trials are recruiting at National Institutes of Health Clinical Center, located at 10 CENTER DR, BLDG. 10 ROOM 2-5940, BETHESDA, MD 20892-0001, phone (301) 496-6353 in Bethesda, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

599 clinical trials at National Institutes of Health Clinical Center

·Clear filters·↓ Download CSV

Genomic Services Research Program

for Colon Cancer

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 105

Code: NCT02595957·Recruiting·Listed Nov 2015

Apply to this trial

Study of Factors Regulating Mast Cell Proliferation

for Mastocytosis

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 80·Accepts healthy volunteers

Code: NCT00044122·Recruiting·Listed Aug 2002

Apply to this trial

MRS Measurement of Glutamate and GABA Metabolism in Brain

for Normal Physiology

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT00109174·Recruiting·Listed Apr 2005

Apply to this trial

Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers

for Neuromuscular Disease

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 2 - 110·Accepts healthy volunteers

Code: NCT01900132·Recruiting·Listed Jul 2013

Apply to this trial

Neural and Psychological Mechanisms of Pain Perception

for Pain

1 location in Bethesda

Sponsor: National Center for Complementary and Integrative Health (NCCIH)

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT02446262·Recruiting·Listed May 2015

Apply to this trial

Clinical and Laboratory Study of Methylmalonic Acidemia

for Organic Acidemia

Sites in Bethesda +1 more location

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 115·Accepts healthy volunteers

Code: NCT00078078·Recruiting·Listed Feb 2004

Apply to this trial

Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

for Genetic Eye Disease

1 location in Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 1 Day - 120

Code: NCT02077894·Recruiting·Listed Mar 2014

Apply to this trial

A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...

for B-All

Sites in Bethesda +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 25

Code: NCT05621291·Recruiting·Listed Nov 2022

Apply to this trial

Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents

for Hypereosinophilic Syndrome

Drug: Dupilumab

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 99

Code: NCT06477653·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

Genetic Analysis of Immune Disorders

for DOK 8

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 101

Code: NCT00001467·Recruiting·Listed Nov 1999

Apply to this trial

Characterization and Treatment of Adolescent Depression

for Depression

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 11 - 25·Accepts healthy volunteers

Code: NCT03388606·Recruiting·Listed Jan 2018

Apply to this trial

Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder

for Mood Disorder

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 7 - 60

Code: NCT00025935·Recruiting·Listed Nov 2001

Apply to this trial

Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma

for Melanoma

2 locations in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 Weeks - 99·Accepts healthy volunteers

Code: NCT00040352·Recruiting·Listed Jun 2002

Apply to this trial

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

for GATA2

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 6 - 70

Code: NCT01861106·Phase 2·Recruiting·Listed May 2013

Apply to this trial

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

for Lymphoma

Sites in Bethesda +2 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT05237986·Recruiting·Listed Feb 2022

Apply to this trial

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

for Astrocytoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06344130·Phase 1·Recruiting·Listed Apr 2024

Apply to this trial

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

for Glioblastoma Multiforme

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT00083512·Recruiting·Listed May 2004

Apply to this trial

Caregiving Networks Across Disease Context and the Life Course

for Inherited Metabolic Disorders

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05007990·Recruiting·Listed Aug 2021

Apply to this trial

Evaluation of Patients With Gastrointestinal Disease

for Lower GI Disease

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 120

Code: NCT05041374·Recruiting·Listed Sep 2021

Apply to this trial

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

for Hematologic Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 120·Accepts healthy volunteers

Code: NCT05327023·Phase 1, Phase 2·Recruiting·Listed Apr 2022

Apply to this trial

Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation

for Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 5 - 70

Code: NCT06093867·Recruiting·Listed Oct 2023

Apply to this trial

Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change

for Overweight

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 50

Code: NCT06325722·Recruiting·Listed Mar 2024

Apply to this trial

Influence of Brain Oscillation-Dependent TMS on Motor Function

for Healthy

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT03288220·Recruiting·Listed Sep 2017

Apply to this trial

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

for Herpes Zoster

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05580458·Phase 1, Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

Evaluation of Patients With Liver Disease

for Hepatitis D

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 2 - 100·Accepts healthy volunteers

Code: NCT00001971·Recruiting·Listed Jan 2000

Apply to this trial

Studies of the Natural History of Rheumatic Diseases

for Rheumatic Diseases

1 location in Bethesda

Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: All·Age: 18 - 100

Code: NCT00024479·Recruiting·Listed Sep 2001

Apply to this trial

Studies of Skin Microbes in Healthy People and in People With Skin Conditions

for Eczema

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 2 - 100·Accepts healthy volunteers

Code: NCT00605878·Recruiting·Listed Jan 2008

Apply to this trial

Screening Volunteers for Clinical Trials

for Screening

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT01375530·Recruiting·Listed Jun 2011

Apply to this trial

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

for Epilepsy

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 8 - 120·Accepts healthy volunteers

Code: NCT02107989·Recruiting·Listed Apr 2014

Apply to this trial

Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders

for Neurological Regression

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Day - 100

Code: NCT00029965·Recruiting·Listed Jan 2002

Apply to this trial

Men at High Genetic Risk for Prostate Cancer

for Prostatic Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 30 - 75

Code: NCT03805919·Recruiting·Listed Jan 2019

Apply to this trial

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 70

Code: NCT06795581·Phase 1·Recruiting·Listed Jan 2025

Apply to this trial

Natural History of Sickle Cell Disease

for Pain Crisis

Sites in Bethesda +1 more location

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 2 - 90

Code: NCT00081523·Recruiting·Listed Apr 2004

Apply to this trial

Study of Proteus Syndrome and Related Congenital Disorders

for Proteus Syndrome

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 99

Code: NCT00001403·Recruiting·Listed Nov 1999

Apply to this trial

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

for Mortality in Sickle Cell

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 100

Code: NCT05213572·Recruiting·Listed Jan 2022

Apply to this trial

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

for Intellectual Disability

1 location in Bethesda

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 8 - 30·Accepts healthy volunteers

Code: NCT05473429·Recruiting·Listed Jul 2022

Apply to this trial

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

for Prostate Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT05588128·Recruiting·Listed Oct 2022

Apply to this trial

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

for Human Immunodeficiency Virus

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03300830·Recruiting·Listed Oct 2017

Apply to this trial

Natural History of Bronchiectasis

for Bronchiectasis

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 5 - 100·Accepts healthy volunteers

Code: NCT00943514·Recruiting·Listed Jul 2009

Apply to this trial

Natural History of Individuals With Immune System Problems That Lead to Fungal Infections

for Chronic Mucocutaneous Candidiasis

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 99·Accepts healthy volunteers

Code: NCT01386437·Recruiting·Listed Jul 2011

Apply to this trial