Clinical Trials at National Institutes of Health Clinical Center

As of July 2026, 593 paid clinical trials are recruiting at National Institutes of Health Clinical Center, located at 10 CENTER DR, BLDG. 10 ROOM 2-5940, BETHESDA, MD 20892-0001, phone (301) 496-6353 in Bethesda, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

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599 clinical trials at National Institutes of Health Clinical Center

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Diagnosis and Treatment of Leishmania Infections

for Leishmaniasis

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 100

Code: NCT00344188·Recruiting·Listed Jun 2006

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Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

for Pancreatic Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 72

Code: NCT02830724·Phase 1, Phase 2·Recruiting·Listed Jul 2016

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Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

for Primary Sclerosing Cholangitis

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04685200·Recruiting·Listed Dec 2020

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Clinical and Genetic Studies of Li-Fraumeni Syndrome

for Li-Fraumeni Syndrome

2 locations in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01443468·Recruiting·Listed Sep 2011

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Children s Growth and Behavior Study

for Obesity

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 8 - 100·Accepts healthy volunteers

Code: NCT02390765·Recruiting·Listed Mar 2015

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PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

for Metastatic Colorectal Cancer (Mcrc)

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT05286814·Phase 2·Recruiting·Listed Mar 2022

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Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial

for Attention Deficit Hyperactivity Disorder

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 8 - 16

Code: NCT05608434·Phase 1, Phase 2·Recruiting·Listed Nov 2022

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Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06694454·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Studies of Disorders With Increased Susceptibility to Fungal Infections

for Fungal Infections

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT01222741·Recruiting·Listed Oct 2010

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Tissue Collection for Studies of Lymph Cancer

for Hodgkin Disease

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT01676805·Recruiting·Listed Aug 2012

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Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

for Thymoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 100

Code: NCT01950572·Recruiting·Listed Sep 2013

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Evaluation of Adults With Endocrine and Metabolic-Related Conditions

for Endocrine Diseases

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT02830308·Recruiting·Listed Jul 2016

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Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

for Alpha and Beta Thalassemia

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT03937817·Recruiting·Listed May 2019

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Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)

for Gastroenteropancreatico Tumors

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 100

Code: NCT04086485·Phase 1, Phase 2·Recruiting·Listed Sep 2019

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Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

for Cone-Rod Degeneration

1 location in Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 5 - 120·Accepts healthy volunteers

Code: NCT04289571·Phase 1·Recruiting·Listed Feb 2020

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Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity

for Androgen Insensitivity Syndrome

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 8 - 99·Accepts healthy volunteers

Code: NCT04708431·Recruiting·Listed Jan 2021

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Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

for Graft vs Host Disease

Drug: Pacritinib

Sites in Bethesda +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT05531786·Phase 1, Phase 2·Recruiting·Listed Sep 2022

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Causes and Natural History of Dyslipidemias

for Hypercholesterolemia

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 2 - 100

Code: NCT00353782·Recruiting·Listed Jul 2006

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Effects of Treatments on Atopic Dermatitis

for Eczema

1 location in Bethesda

Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: All·Age: 2 - 50·Accepts healthy volunteers

Code: NCT01631617·Phase 2·Recruiting·Listed Jun 2012

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Spironolactone for Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

1 location in Bethesda

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 18 - 100

Code: NCT01712620·Phase 2·Recruiting·Listed Oct 2012

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Deep Brain Stimulation Therapy in Movement Disorders

for Parkinson's Disease

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 100

Code: NCT02119611·Recruiting·Listed Apr 2014

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Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

for Severe Aplastic Anemia

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 2 - 99

Code: NCT05012111·Recruiting·Listed Aug 2021

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Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

for HIV

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 120·Accepts healthy volunteers

Code: NCT05470491·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Gene

for Genotype

1 location in Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 18 - 120

Code: NCT01145196·Recruiting·Listed Jun 2010

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A Prospective Natural History Study of Lymphatic Anomalies

for Lymphatic Diseases

Sites in Bethesda +1 more location

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 1 Day - 100·Accepts healthy volunteers

Code: NCT05731141·Recruiting·Listed Feb 2023

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Evaluation for NCI Surgery Branch Clinical Research Protocols

for Synovial Cell Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT00001823·Recruiting·Listed Nov 1999

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Inherited Reproductive Disorders

for Genetic Disorder

Sites in Bethesda +1 more location

Sponsor: National Institute of Environmental Health Sciences (NIEHS)

Sex: All·Age: 6 Weeks - 120

Code: NCT01500447·Recruiting·Listed Dec 2011

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Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

for Peripheral T-cell Lymphomas

Sites in Bethesda +1 more location

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 120·Accepts healthy volunteers

Code: NCT03922724·Phase 2·Recruiting·Listed Apr 2019

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Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

for Neurofibromatosis 1

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT04750928·Phase 1, Phase 2·Recruiting·Listed Feb 2021

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Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

for Acute Ovarian Failure

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: Female·Age: 4 - 35

Code: NCT05440617·Recruiting·Listed Jul 2022

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Thrombosis and Inflammation in Vessels Initiative (TIVI)

for Cardiovascular Diseases

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 5 - 100·Accepts healthy volunteers

Code: NCT06552767·Recruiting·Listed Aug 2024

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Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

for Immune System Diseases

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 - 100

Code: NCT00001406·Recruiting·Listed Nov 1999

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Study of Mycobacterial Infections

for Mycobacterium Infections

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: Up to 100·Accepts healthy volunteers

Code: NCT00018044·Recruiting·Listed Jun 2001

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Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

for Graft-versus-leukemia

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 7 - 80·Accepts healthy volunteers

Code: NCT00106925·Recruiting·Listed Apr 2005

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Deep Brain Stimulation Surgery for Movement Disorders

for Parkinson's Disease

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 99

Code: NCT01581580·Recruiting·Listed Apr 2012

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Natural History and Development of Spondyloarthritis

for Arthritis

1 location in Bethesda

Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: All·Age: 2 - 99·Accepts healthy volunteers

Code: NCT01422694·Recruiting·Listed Aug 2011

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The Mechanistic Biology of Primary Immunodeficiency Disorders

for Primary Immunodeficiency Disorders

Sites in Bethesda +1 more location

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 90·Accepts healthy volunteers

Code: NCT03394053·Recruiting·Listed Jan 2018

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Children and Adults With Chordoma

for Chordoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+

Code: NCT03910465·Recruiting·Listed Apr 2019

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Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

for Sickle Cell

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03685721·Recruiting·Listed Sep 2018

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Leukapheresis to Obtain Plasma or Lymphocytes for Studies of HIV-infected Patients, Including Long-term Non-progressors

for HIV

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 100

Code: NCT00029445·Recruiting·Listed Jan 2002

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