Clinical Trials at National Institutes of Health Clinical Center

As of July 2026, 593 paid clinical trials are recruiting at National Institutes of Health Clinical Center, located at 10 CENTER DR, BLDG. 10 ROOM 2-5940, BETHESDA, MD 20892-0001, phone (301) 496-6353 in Bethesda, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 21, 2026.

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599 clinical trials at National Institutes of Health Clinical Center

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NIAID Centralized Sequencing Protocol

for Atopy

Sites in Bethesda +1 more location

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 100·Accepts healthy volunteers

Code: NCT03206099·Recruiting·Listed Jul 2017

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A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

for Brain Tumor

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 15+

Code: NCT05588141·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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Natural History of Inflammatory Muscle Diseases

for Inflammation In Skeletal Muscle

1 location in Bethesda

Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: All·Age: 2 - 120·Accepts healthy volunteers

Code: NCT05738824·Recruiting·Listed Feb 2023

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Screening for Research Participants

for Eye Diseases

1 location in Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 2 - 100·Accepts healthy volunteers

Code: NCT00655096·Recruiting·Listed Apr 2008

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The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

for Thyroid Cancer

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 90

Code: NCT03841617·Phase 2·Recruiting·Listed Feb 2019

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Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

for Chronic Graft vs. Host Disease

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 120

Code: NCT00092235·Recruiting·Listed Sep 2004

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Use of Cysteamine in the Treatment of Cystinosis

for Cystinosis

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Week - 115

Code: NCT00359684·Recruiting·Listed Aug 2006

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Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

for Mood Disorders

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 3 - 99·Accepts healthy volunteers

Code: NCT00024635·Recruiting·Listed Apr 2005

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The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

for Neurologic Disorders

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 6 Weeks+·Accepts healthy volunteers

Code: NCT00271622·Recruiting·Listed Jan 2006

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Evaluation of Children With Endocrine and Metabolic-Related Conditions

for Adrenal Insufficiency

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 3 Months - 100

Code: NCT02769975·Recruiting·Listed May 2016

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Vascular Disease Discovery Protocol

for Vascular Dysfunction

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 2 - 100·Accepts healthy volunteers

Code: NCT03538639·Recruiting·Listed May 2018

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Longitudinal Studies of Patient With FPDMM

for Inherited Hematological Diseases

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Day - 100·Accepts healthy volunteers

Code: NCT03854318·Recruiting·Listed Feb 2019

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Developing Brain, Impulsivity and Compulsivity

for Typical Development

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 6 - 80

Code: NCT04631042·Recruiting·Listed Nov 2020

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Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy

for Turner Syndrome

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 2 - 35

Code: NCT04948658·Recruiting·Listed Jul 2021

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PT-112 in Subjects With Thymoma and Thymic Carcinoma

for Thymic Epithelial Tumor

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT05104736·Phase 2·Recruiting·Listed Nov 2021

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Natural History Protocol for Movement Disorders

for Movement Disorder

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 2 - 100·Accepts healthy volunteers

Code: NCT05413291·Recruiting·Listed Jun 2022

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MEHMO Natural History and Biomarkers

for Intellectual Disability

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 1 Week - 100

Code: NCT06019182·Recruiting·Listed Aug 2023

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Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

for Adenocarcinoma of the Bladder

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06041503·Phase 2·Recruiting·Listed Sep 2023

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Diagnosis and Management of Inflammatory and Infectious Diseases

for Infection

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 100

Code: NCT00557726·Recruiting·Listed Nov 2007

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Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer

for Prostatic Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT03354416·Recruiting·Listed Nov 2017

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Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic Dermatitis

for Milk and/or Peanut Allergy

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 21

Code: NCT03835767·Phase 2·Recruiting·Listed Feb 2019

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Study of Lung Proteins in Patients With Pneumonia

for Pneumonia

1 location in Bethesda

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 3 - 99

Code: NCT00077909·Recruiting·Listed Feb 2004

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Belimumab With Rituximab for Primary Membranous Nephropathy

for Membranous Nephropathy

Drug: Rituximab

Sites in Bethesda, Baltimore +18 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 75

Code: NCT03949855·Phase 2·Recruiting·Listed May 2019

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Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

for Dry Age-Related Macular Degeneration

Sites in Bethesda & Baltimore

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 55 - 95

Code: NCT04339764·Phase 1, Phase 2·Recruiting·Listed Apr 2020

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Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols

for Multiple Myeloma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT02682667·Recruiting·Listed Feb 2016

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Psychological Treatments for Youth With Severe Irritability.

for Irritability

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 8 - 17

Code: NCT02531893·Recruiting·Listed Aug 2015

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Natural History of Familial Carcinoid Tumor

for Carcinoid

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 100

Code: NCT00646022·Recruiting·Listed Mar 2008

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Study of Endocrine-Related Conditions and Physiology

for Endocrine Disease

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 90

Code: NCT03867448·Recruiting·Listed Mar 2019

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Immune Regulation in Ulcerative Colitis or Crohn s Disease

for Inflammatory Bowel Disease

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 75·Accepts healthy volunteers

Code: NCT00001184·Recruiting·Listed Nov 1999

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Study of Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

1 location in Bethesda

Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: All·Age: 3 - 120·Accepts healthy volunteers

Code: NCT00001372·Recruiting·Listed Nov 1999

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Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use

for Blood Donors

1 location in Bethesda

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT00001846·Recruiting·Listed Nov 1999

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Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

for Mesothelioma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06885697·Phase 1·Recruiting·Listed Mar 2025

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Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

for Neuropsychiatric Disorder

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 1 Day - 99·Accepts healthy volunteers

Code: NCT01778504·Recruiting·Listed Jan 2013

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NIAAA Natural History Protocol

for Alcohol Use Disorder

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT02231840·Recruiting·Listed Sep 2014

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Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

for Normal Physiology

1 location in Bethesda

Sponsor: National Center for Complementary and Integrative Health (NCCIH)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT03258580·Recruiting·Listed Aug 2017

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Apheresis of Patients With Immunodeficiency

for LAD-1

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 40

Code: NCT01212055·Recruiting·Listed Sep 2010

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Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.

for Cerebral Palsy

1 location in Bethesda

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 5 - 25·Accepts healthy volunteers

Code: NCT06498596·Recruiting·Listed Jul 2024

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Psychological Benefits of a Normalized Camping Experience for Children With Cancer

for Pediatric Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 7 - 25

Code: NCT00001186·Recruiting·Listed Nov 1999

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Natural History Study of Parathyroid Disorders

for Parathyroid Cancer

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 6 Months - 100

Code: NCT04969926·Recruiting·Listed Jul 2021

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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers

for Cardiovascular Disease

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT04216342·Phase 1·Recruiting·Listed Jan 2020

Apply to this trial