Paid Clinical Trials in Bethesda, MD

As of September 2026, 892 paid clinical trials are recruiting in Bethesda, Maryland. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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794 clinical trials

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Natural History and Genetics of Food Allergy and Related Conditions

for Food Allergy

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 99·Accepts healthy volunteers

Code: NCT02504853·Recruiting·Listed Jul 2015

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Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

for Peritoneal Mesothelioma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT04847063·Phase 1·Recruiting·Listed Apr 2021

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Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

for Pheochromocytoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 100

Code: NCT03206060·Phase 2·Recruiting·Listed Jul 2017

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Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors

for Advanced Malignant Solid Neoplasm

Drug: Peposertib

Sites in Bethesda +5 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687136·Phase 1·Recruiting·Listed Jan 2023

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A Natural History Study of Bone and Mineral Disorders

for Tumor Induced Osteomalcia

1 location in Bethesda

Sponsor: National Institute of Dental and Craniofacial Research (NIDCR)

Sex: All·Age: 1 Day - 100

Code: NCT00024804·Recruiting·Listed Oct 2001

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Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients

for Autoimmune Lymphoproliferative Syndrome

Drug: Soquelitinib

Sites in Bethesda +2 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 16 - 120

Code: NCT06730126·Phase 2·Recruiting·Listed Dec 2024

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Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

for Cardiovascular Disease

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT03372733·Phase 2·Recruiting·Listed Dec 2017

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Studies of the Natural History of Rheumatic Diseases

for Rheumatic Diseases

1 location in Bethesda

Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Sex: All·Age: 18 - 100

Code: NCT00024479·Recruiting·Listed Sep 2001

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PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

for Kaposi Sarcoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 99

Code: NCT04303117·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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Natural History of KSHV-Associated Multicentric Castleman s Disease

for Multicentric Castleman s Disease

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04968288·Recruiting·Listed Jul 2021

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Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

for Neurofibromatosis 1

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05361811·Recruiting·Listed May 2022

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Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)

for KSHV Inflammatory Cytokine Syndrome (KICS)

Drug: Pacritinib

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06052618·Phase 2·Recruiting·Listed Sep 2023

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Top-Down Attentional Control of Visual-Processing

for Focal Brain Lesion

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT01087281·Recruiting·Listed Mar 2010

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Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

for Neuropsychiatric Disorder

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 30 Days - 99·Accepts healthy volunteers

Code: NCT01778504·Recruiting·Listed Jan 2013

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Genetic Studies of Insulin and Diabetes

for Diabetes Mellitus

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 6 Months - 120·Accepts healthy volunteers

Code: NCT00001987·Recruiting·Listed Jan 2000

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Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

for Pancreatic Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 72

Code: NCT03190941·Phase 1, Phase 2·Recruiting·Listed Jun 2017

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Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

for Alcohol Dependence

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT02108080·Recruiting·Listed Apr 2014

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Admission and Management of Occupational or Other Exposures to Biodefense/Bioterrorism Agents or to Epidemic/Emerging Infectious Diseases

for Occupational Accidents

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 99·Accepts healthy volunteers

Code: NCT01200953·Recruiting·Listed Sep 2010

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Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

for Neurofibroma, Plexiform

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3 - 35

Code: NCT02390752·Phase 1·Recruiting·Listed Mar 2015

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Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

for Malignancy, Hematologic

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06904066·Phase 1·Recruiting·Listed Apr 2025

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Natural History, Pathogenesis, and Outcome of Ocular Disorders

for Eye Disease

1 location in Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 2 - 100

Code: NCT02821767·Recruiting·Listed Jul 2016

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NIAAA Natural History Protocol

for Alcohol Use Disorder

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT02231840·Recruiting·Listed Sep 2014

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Studies of Disorders With Increased Susceptibility to Fungal Infections

for Fungal Infections

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT01222741·Recruiting·Listed Oct 2010

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Nicotinic Receptor Genetic Variation and Alcohol Reward

for Alcohol Drinking

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 21 - 60·Accepts healthy volunteers

Code: NCT03294460·Phase 1·Recruiting·Listed Sep 2017

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Blood Sampling for Research Related to Sickle Cell Disease

for Sickle Cell Trait

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT00542230·Recruiting·Listed Oct 2007

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Natural History of Familial Carcinoid Tumor

for Carcinoid

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 100

Code: NCT00646022·Recruiting·Listed Mar 2008

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Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques

for Multiple Sclerosis

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 120

Code: NCT02784210·Phase 2·Recruiting·Listed May 2016

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Tirzepatide in MetALD

for Metabolic Alcohol-associated Liver Disease

Drug: Tirzepatide

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 21 - 100

Code: NCT07046819·Phase 2·Recruiting·Listed Jul 2025

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Inflammatory and Infectious Diseases of the Nervous System

for Brain Disease

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 2 - 110

Code: NCT02435810·Recruiting·Listed May 2015

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A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

for Melanoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 72

Code: NCT02621021·Phase 2·Recruiting·Listed Dec 2015

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Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies

for Costello Syndrome

Sites in Bethesda & Rockville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 Month - 99·Accepts healthy volunteers

Code: NCT04888936·Recruiting·Listed May 2021

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Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

for Malignant Solid Neoplasm

Sites in Bethesda +3 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03750227·Phase 3·Recruiting·Listed Nov 2018

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PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

for Long COVID

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06920628·Phase 1·Recruiting·Listed Apr 2025

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Sample Collection and Tracking for the Developmental Therapeutics Clinic

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03269578·Recruiting·Listed Sep 2017

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Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

for Prostate Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT04692675·Recruiting·Listed Jan 2021

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Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents

for Hypereosinophilic Syndrome

Drug: Dupilumab

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 99

Code: NCT06477653·Phase 2·Recruiting·Listed Jun 2024

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Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

for Lymphoproliferative Disorders

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 - 69

Code: NCT04339777·Phase 2·Recruiting·Listed Apr 2020

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Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers

for Healthy

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 101·Accepts healthy volunteers

Code: NCT06874205·Phase 1·Recruiting·Listed Mar 2025

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Natural History of Individuals With Immune System Problems That Lead to Fungal Infections

for Chronic Mucocutaneous Candidiasis

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 1 Day - 99·Accepts healthy volunteers

Code: NCT01386437·Recruiting·Listed Jul 2011

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A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

for AMPD3, OMIM*102772, AMP Deaminase Deficiency

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 100

Code: NCT06092346·Recruiting·Listed Oct 2023

Apply to this trial