Paid Clinical Trials in Bethesda, MD

As of August 2026, 900 paid clinical trials are recruiting in Bethesda, Maryland. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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Healthy volunteers only

803 clinical trials

MEHMO Natural History and Biomarkers

for Intellectual Disability

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 1 Week - 100

Code: NCT06019182·Recruiting·Listed Aug 2023

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Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

for Adenocarcinoma of the Bladder

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06041503·Phase 2·Recruiting·Listed Sep 2023

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Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer

for Prostatic Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT03354416·Recruiting·Listed Nov 2017

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Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic Dermatitis

for Milk and/or Peanut Allergy

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 21

Code: NCT03835767·Phase 2·Recruiting·Listed Feb 2019

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Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

for Dry Age-Related Macular Degeneration

Sites in Bethesda & Baltimore

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 55 - 95

Code: NCT04339764·Phase 1, Phase 2·Recruiting·Listed Apr 2020

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Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

for Malignant Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00026884·Recruiting·Listed Nov 2001

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COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study

for Alcohol Drinking

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT04391816·Recruiting·Listed May 2020

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Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

for Total Thyroidectomy

Sites in Bethesda & Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06383091·Recruiting·Listed Apr 2024

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Training Protocol on the Natural History of Tuberculosis

for Mycobacterium Infections

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 2 - 100

Code: NCT01212003·Recruiting·Listed Sep 2010

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NIAAA Natural History Protocol

for Alcohol Use Disorder

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT02231840·Recruiting·Listed Sep 2014

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Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

for Gastric Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 6+

Code: NCT04557969·Recruiting·Listed Sep 2020

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Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.

for Cerebral Palsy

1 location in Bethesda

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 5 - 25·Accepts healthy volunteers

Code: NCT06498596·Recruiting·Listed Jul 2024

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Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis

for HAM/TSP

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 120

Code: NCT04799288·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

for Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)

Drug: Ruxolitinib

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75·Accepts healthy volunteers

Code: NCT05398809·Phase 2·Recruiting·Listed Jun 2022

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Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 85

Code: NCT03986034·Phase 2·Recruiting·Listed Jun 2019

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5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03366116·Phase 1·Recruiting·Listed Dec 2017

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Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

for Prostate Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3+

Code: NCT01441089·Recruiting·Listed Sep 2011

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Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

for Brain Mapping

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT01266577·Recruiting·Listed Dec 2010

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Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal Cancer

for Non-GI Cancers

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT01313442·Recruiting·Listed Mar 2011

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Study of Inherited Neurological Disorders

for Motor Neuron Disease

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 2 - 120

Code: NCT00004568·Recruiting·Listed Feb 2000

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Natural History of Depression, Bipolar Disorder and Suicide Risk

for Behavioral Symptoms

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 120

Code: NCT06462196·Recruiting·Listed Jun 2024

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A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

for Carcinoma, Neuroendocrine

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06406465·Phase 2·Recruiting·Listed May 2024

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Role of Genetic Factors in the Development of Lung Disease

for Cystic Fibrosis

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 2 - 90·Accepts healthy volunteers

Code: NCT00001532·Recruiting·Listed Nov 1999

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Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques

for Multiple Sclerosis

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 120

Code: NCT02784210·Phase 2·Recruiting·Listed May 2016

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Metabolic Profiling of Immune Responses in Immune-mediated Diseases

for Primary Immunodeficiency

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT04864886·Recruiting·Listed Apr 2021

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Collection of Blood From Patients With Prostate Cancer

for Cancer Of Prostate

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT00923221·Recruiting·Listed Jun 2009

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Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

for Idiopathic CD4+ Lymphocytopenia

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00867269·Recruiting·Listed Mar 2009

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Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors

for Advanced Malignant Solid Neoplasm

Drug: Peposertib

Sites in Bethesda +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687136·Phase 1·Recruiting·Listed Jan 2023

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CHIP/CCUS Natural History Protocol

for Clonal Hematopoiesis of Indeterminate Potential

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 99

Code: NCT04102423·Recruiting·Listed Sep 2019

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National Eye Institute Biorepository for Retinal Diseases

for Age-Related Macular Degeneration

1 location in Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 2 - 120·Accepts healthy volunteers

Code: NCT01496625·Recruiting·Listed Dec 2011

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Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

for Malignant Solid Neoplasm

Sites in Bethesda +3 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03750227·Phase 3·Recruiting·Listed Nov 2018

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Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

for Healthy Volunteers

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06484075·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

for Kidney Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00033137·Recruiting·Listed Apr 2002

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Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies

for Influenza

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04772170·Recruiting·Listed Feb 2021

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Novel Genetic Disorders of the Immune System

for PI3KCD

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 99

Code: NCT02257892·Recruiting·Listed Oct 2014

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Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

for Malaria

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT02639299·Recruiting·Listed Dec 2015

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Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

for Healthy Volunteer

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT03065335·Phase 1·Recruiting·Listed Feb 2017

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Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression

for Depression

1 location in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 18 - 70

Code: NCT03973268·Phase 1·Recruiting·Listed Jun 2019

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Human Milk Oligosaccharide-Based Synbiotic Supplement for Intestinal Microbiota Dysbiosis

for Healthy Volunteers

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06615986·EARLY_Phase 1·Recruiting·Listed Sep 2024

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Controls and Healthy Vasculature Initiative

for Vascular And Immunologic Diseases

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT05403151·Recruiting·Listed Jun 2022

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