Clinical Trials at Boston Children's Hospital

As of July 2026, 214 paid clinical trials are recruiting at Boston Children's Hospital, located at 11 HEREFORD ST, APT 4R, BOSTON, MA 02115-1602, phone (617) 602-9730 in Boston, Massachusetts. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

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220 clinical trials at Boston Children's Hospital

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Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology

for Enteral Feeding Intolerance

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1+

Code: NCT04900597·Recruiting·Listed May 2021

Apply to this trial

NIRS Monitoring in Premature Infants

for Hemorrhage

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Months - 12 Months·Accepts healthy volunteers

Code: NCT02601339·Recruiting·Listed Nov 2015

Apply to this trial

Study of Normal Intestinal Development and Disease in Premature and Term Neonates

for NEC

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 2

Code: NCT06681129·Recruiting·Listed Nov 2024

Apply to this trial

Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress

for Li-Fraumeni Syndrome

3 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: All ages

Code: NCT04541654·Recruiting·Listed Sep 2020

Apply to this trial

Gene Discovery Core, The Manton Center

for Undiagnosed Conditions

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT02743845·Recruiting·Listed Apr 2016

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Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences

for Family Reported Errors and Adverse Events

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05407129·Recruiting·Listed Jun 2022

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A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies

for Acute Myeloid Leukemia

2 locations in Boston

Sponsor: Franziska Wachter

Sex: All·Age: 1 - 39

Code: NCT05796570·Phase 2·Recruiting·Listed Apr 2023

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Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

for Brief Resolved Unexplained Event

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Months - 12 Months

Code: NCT04477460·Recruiting·Listed Jul 2020

Apply to this trial

Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

for Dysphagia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04504227·Recruiting·Listed Aug 2020

Apply to this trial

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

for Hereditary Spastic Paraplegia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 30·Accepts healthy volunteers

Code: NCT04712812·Recruiting·Listed Jan 2021

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Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

for Hereditary Spastic Paraplegia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Month - 30

Code: NCT05354622·Recruiting·Listed Apr 2022

Apply to this trial

CF Wellness Program

for Cystic Fibrosis (CF)

Sites in Boston +2 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07071324·Recruiting·Listed Jul 2025

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Fecal Microbiota Transplant National Registry

for Fecal Microbiota Transplantation

Sites in Boston, Worcester +26 more locations

Sponsor: American Gastroenterological Association

Sex: All·Age: All ages

Code: NCT03325855·Recruiting·Listed Oct 2017

Apply to this trial

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

Sites in Boston +21 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting·Listed Oct 2024

Apply to this trial

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

for Patellar Dislocation, Recurrent

Sites in Boston +15 more locations

Sponsor: Hospital for Special Surgery, New York

Sex: All·Age: 10 - 35

Code: NCT06883396·Recruiting·Listed Mar 2025

Apply to this trial

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

for Sarcoma

3 locations in Boston

Sponsor: David S Shulman, MD

Sex: All·Age: 12 - 49

Code: NCT06709495·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

for Failed or Difficult Intubation, Sequela

Sites in Boston, Springfield +49 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02493478·Recruiting·Listed Jul 2015

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Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome

for Genetic Disease

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT05528744·Recruiting·Listed Sep 2022

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Optimal Ventilation for Cardiac Arrest

for Cardiac Arrest (CA)

Sites in Boston +19 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 37 Weeks - 18

Code: NCT07114510·Recruiting·Listed Aug 2025

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Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

for Congenital Fibrosis of Extraocular Muscles

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Day+·Accepts healthy volunteers

Code: NCT03059420·Recruiting·Listed Feb 2017

Apply to this trial

PediRISE Feasibility

for Pediatric Cancer

Sites in Boston +3 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06283251·Recruiting·Listed Feb 2024

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Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

for Sickle Cell Disease

1 location in Boston

Sponsor: Daniel Bauer

Sex: All·Age: 13 - 40

Code: NCT06647979·Phase 1·Recruiting·Listed Oct 2024

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Low Dose IL-2 for the Treatment of Crohn's Disease

for Crohn Disease

Sites in Boston +2 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 12 - 80

Code: NCT04263831·Phase 1, Phase 2·Recruiting·Listed Feb 2020

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OnTrackCF: Engagement, Feasibility, and Acceptability Study

for Cystic Fibrosis (CF)

Sites in Boston +2 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 18+

Code: NCT07031323·Recruiting·Listed Jun 2025

Apply to this trial

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Boston +67 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

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Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

for Congenital Heart Disease

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Day - 7 Days

Code: NCT06434207·Recruiting·Listed May 2024

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Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency

for Succinic Semialdehyde Dehydrogenase Deficiency

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT03758521·Recruiting·Listed Nov 2018

Apply to this trial

Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

for Drug Effect

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Days - 17

Code: NCT03593408·Recruiting·Listed Jul 2018

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Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery

for Heart Surgery

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 17

Code: NCT06721455·Recruiting·Listed Dec 2024

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Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis

for Sepsis

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Month - 17

Code: NCT04103268·Recruiting·Listed Sep 2019

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Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery

for Congenital Heart Disease

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT04299828·Recruiting·Listed Mar 2020

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Neurofibromatosis Type 1 Tumor Early Detection Study

for Neurofibromatosis Type 1

1 location in Boston

Sponsor: David Miller

Sex: All·Age: 18+

Code: NCT06515860·Recruiting·Listed Jul 2024

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Language During Inhalational Induction

for Emergence Delirium

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 5 - 10

Code: NCT06324955·Recruiting·Listed Mar 2024

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Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia

for Hypoxic Ischemic Brain Injury

3 locations in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 2

Code: NCT02793999·Recruiting·Listed Jun 2016

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Transplantation of Autologously Derived Mitochondria Following Ischemia

for Extracorporeal Membrane Oxygenation Complication

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 17

Code: NCT02851758·Recruiting·Listed Aug 2016

Apply to this trial

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

Sites in Boston +17 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting·Listed Nov 2024

Apply to this trial

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

for Stress

2 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 12 - 25·Accepts healthy volunteers

Code: NCT06038318·Recruiting·Listed Sep 2023

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Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma

for Relapsed Neuroblastoma

2 locations in Boston

Sponsor: Roberto Chiarle

Sex: All·Age: 12 Months - 29

Code: NCT06803875·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Boston, Worcester +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

for Pain, Postoperative

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 8 - 35·Accepts healthy volunteers

Code: NCT04439552·Recruiting·Listed Jun 2020

Apply to this trial