Paid Clinical Trials in Boston, MA
As of September 2026, 2,914 paid clinical trials are recruiting in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Boston offers studies at sites including Massachusetts General Hospital for conditions such as Breast Cancer, Prostate Cancer, Ovarian Cancer, Colorectal Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Boston
Trials by drug in Boston
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Newly added in Boston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa
Outcomes of Neurosurgical Tone Management
Post-Prandial Carbohydrate Metabolism in Individuals With and Without Post-Bariatric Surgery Hypoglycemia (PBH)
Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
2,520 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Phase 2 Study to Assess the Safety and Efficacy of ANG003
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
A Study of Brenipatide in Participants With Opioid Use Disorder
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Study of DONQ52 in Active Celiac Disease
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study of Brenipatide in Participants With Alcohol Use Disorder
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Top Research Study Locations in Boston
Researchers run research studies in Boston, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Massachusetts General Hospital | Breast Cancer, Advanced Solid Tumor, Colorectal Cancer | 693 |
| Brigham and Women's Hospital | Obesity, Prostate Cancer, Breast Cancer | 356 |
| Dana-Farber Cancer Institute | Breast Cancer, Acute Myeloid Leukemia, Metastatic Breast Cancer | 344 |
| Boston Children's Hospital | Congenital Heart Disease, Cystic Fibrosis, Sickle Cell Disease | 259 |
| Beth Israel Deaconess Medical Center | Multiple Myeloma, Lymphoma, Acute Myeloid Leukemia | 258 |
| Dana Farber Cancer Institute | Breast Cancer, Ovarian Cancer, Prostate Cancer | 217 |
| Tufts Medical Center | Heart Failure, Acute Myeloid Leukemia, Acute Respiratory Distress Syndrome | 111 |
| Boston Medical Center | Amblyopia, Alpha1-Antitrypsin Deficiency, Anatomic Stage II Breast Cancer AJCC v8 | 92 |
| Massachusetts General Hospital Cancer Center | Breast Cancer, Coping Skills, B Acute Lymphoblastic Leukemia | 52 |
| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | Chronic Obstructive Pulmonary Disease, Mild Traumatic Brain Injury, Prostate Cancer | 30 |
| Brigham & Women's Hospital | Attention, Chronic Lymphocytic Leukemia, Critical Illness | 26 |
| Boston University | Obsessive-Compulsive Disorder, Adolescent Behavior Problem, Alzheimer Disease | 23 |
| Joslin Diabetes Center | Type 1 Diabetes Mellitus, Type 1 Diabetes (T1D), Hypoglycemia | 23 |
| Mass General Brigham | Heart Failure, Heart Failure With Preserved Ejection Fraction, Advanced Solid Tumors | 23 |
| Northeastern University | Cognitive Change, Autism Spectrum Disorder (ASD), Healthy | 22 |
| Massachusetts Eye and Ear | Cone Rod Dystrophy, Glaucoma, Juvenile Macular Degeneration | 16 |
| Brigham and Womens Hospital | Advanced Prostate Cancer, Alpha1-Antitrypsin Deficiency, Alzheimers Disease | 13 |
| Ophthalmic Consultants of Boston | Neovascular Age-related Macular Degeneration, Macular Edema Secondary to Inflammation, Age-Related Macular Degeneration | 13 |
| Adams Clinical Boston | Depressive Disorder, Major, Major Depressive Disorder, Alcohol Use Disorder | 12 |
| Mass General Hospital | Biliary Tract Cancer (BTC), PDAC - Pancreatic Ductal Adenocarcinoma, AML | 12 |
| Massachusetts Eye and Ear Infirmary | Laryngeal Dystonia, Stargardt Disease, Age-related Macular Degeneration | 12 |
| Clinical Trial Site | Transthyretin Amyloidosis With Cardiomyopathy, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency | 11 |
| Boston Childrens Hospital | CSTB-related Disease, Crohn's Disease, Cystic Fibrosis | 11 |
| Beth Israel Deaconess Medical Center (BIDMC) | Prostate Cancer, Advanced Melanoma, Endometrial Cancer | 9 |
| GSK Investigational Site | Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms | 8 |
Active & Upcoming Studies in Boston (2026)
Recruiting trials in Boston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (883 active studies)
- Early Intervention · Massachusetts General Hospital
- Losartan and Paclitaxel in Platinum Resistant Ovarian Cancer · Phase 2 · Massachusetts General Hospital
Neurology & pain (221 active studies)
- Relationships Among Pupil Responses to Light, Circadian Rhythms, and Sleep · Elizabeth B Klerman MD PhD
- Mindfulness Therapy for Chronic Pain After Intimate Partner Violence · Brigham and Women's Hospital
Cardiovascular (191 active studies)
- Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · Brigham and Women's Hospital
- Beta-2 Adrenergic Receptor Polymorphic Variants: An Endotype of Salt Sensitive Hypertension (Beta2AR). · Brigham and Women's Hospital
Diabetes & metabolic (100 active studies)
- Adiposity Distribution in Acute Respiratory Failure · Maurizio F. Cereda, MD
- Creating Linked Inpatient CGM for Kids · Boston Children's Hospital
Mental health & behavior (89 active studies)
- Whole Selves User Testing and Feasibility Study · Boston University
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
Pediatric (63 active studies)
- Reference Range Study for the Quantra System With the QPlus Cartridge in Pediatric Patients · HemoSonics LLC
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
HIV / STI (34 active studies)
- Intervention to Reduce Implicit Bias in Pharmacies · Massachusetts General Hospital
- Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP · Boston Children's Hospital
Eye & vision (33 active studies)
- Glaucoma Drop Aids Part 2 · Boston Medical Center
- Study of Remimazolam for Cataract Surgery · Phase 4 · Fred E, Shapiro
Vaccines (16 active studies)
- A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age · Phase 3 · GlaxoSmithKline
- Sauna for Long Covid · Massachusetts General Hospital
Common conditions studied in Boston
- Breast Cancer (64 active studies)
- Prostate Cancer (42 active studies)
- Ovarian Cancer (38 active studies)
- Colorectal Cancer (34 active studies)
- Heart Failure (34 active studies)
- Endometrial Cancer (33 active studies)
Leading research sponsors in Boston
- Massachusetts General Hospital
- Brigham and Women's Hospital
- Dana-Farber Cancer Institute
- Boston Children's Hospital
- Beth Israel Deaconess Medical Center
Frequently asked questions
How many paid clinical trials are currently recruiting in Boston?
There are approximately 2,914 recruiting clinical trials in Boston, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Boston pay participants?
Most recruiting trials in Boston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Boston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Boston?
The most common conditions under active study in Boston include Breast Cancer (64), Prostate Cancer (42), Ovarian Cancer (38), Colorectal Cancer (34), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Boston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Boston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Boston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Boston?
Recruiting research sites in Boston include Massachusetts General Hospital, Brigham and Women's Hospital, Dana-Farber Cancer Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Boston right now?
The largest active categories in Boston are Cancer & tumors (883), Neurology & pain (221), Cardiovascular (191). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.