Paid Clinical Trials in Boston, MA
As of August 2026, 2,876 paid clinical trials are recruiting in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Boston offers studies at sites including Massachusetts General Hospital for conditions such as Breast Cancer, Prostate Cancer, Heart Failure, Ovarian Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Boston
Trials by drug in Boston
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Newly added in Boston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Ecological Momentary Intervention for Post-Stroke Anomia
Artificial Intelligence-Based Health Assessment From Face Photographs - Healthy Volunteer Study
A Study in Patients With Metastatic Castration-Resistant Prostate Cancer
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC
Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care
2,490 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study of Brenipatide in Participants With Opioid Use Disorder
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
Study of DONQ52 in Active Celiac Disease
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
A Study of Brenipatide in Participants With Alcohol Use Disorder
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
Top Research Study Locations in Boston
Researchers run research studies in Boston, MA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Massachusetts General Hospital | Breast Cancer, Heart Failure, Colorectal Cancer | 689 |
| Brigham and Women's Hospital | Breast Cancer, Obesity, Prostate Cancer | 348 |
| Dana-Farber Cancer Institute | Breast Cancer, Acute Myeloid Leukemia, Multiple Myeloma | 344 |
| Beth Israel Deaconess Medical Center | Multiple Myeloma, Breast Cancer, Lymphoma | 264 |
| Boston Children's Hospital | Congenital Heart Disease, Cystic Fibrosis, Sickle Cell Disease | 263 |
| Dana Farber Cancer Institute | Breast Cancer, Ovarian Cancer, Prostate Cancer | 219 |
| Tufts Medical Center | Heart Failure, Acute Myeloid Leukemia, Acute Respiratory Distress Syndrome | 111 |
| Boston Medical Center | Amblyopia, Alpha1-Antitrypsin Deficiency, Anatomic Stage II Breast Cancer AJCC v8 | 95 |
| Massachusetts General Hospital Cancer Center | Breast Cancer, Coping Skills, B Acute Lymphoblastic Leukemia | 56 |
| VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | Chronic Obstructive Pulmonary Disease, Mild Traumatic Brain Injury, Prostate Cancer | 28 |
| Brigham & Women's Hospital | Attention, Chronic Lymphocytic Leukemia, Critical Illness | 25 |
| Boston University | Obsessive-Compulsive Disorder, Adolescent Behavior Problem, Alzheimer Disease | 24 |
| Joslin Diabetes Center | Type 1 Diabetes Mellitus, Type 1 Diabetes (T1D), Diabetes Mellitus, Type 1 | 23 |
| Mass General Brigham | Heart Failure, Heart Failure With Preserved Ejection Fraction, Advanced Solid Tumors | 23 |
| Northeastern University | Cognitive Change, Autism Spectrum Disorder (ASD), Healthy | 21 |
| Massachusetts Eye and Ear | Cone Rod Dystrophy, Glaucoma, Juvenile Macular Degeneration | 16 |
| Massachusetts Eye and Ear Infirmary | Laryngeal Dystonia, Stargardt Disease, Age-related Macular Degeneration | 13 |
| Clinical Trial Site | Transthyretin Amyloidosis With Cardiomyopathy, Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency | 12 |
| Brigham and Womens Hospital | Advanced Prostate Cancer, Alpha1-Antitrypsin Deficiency, Alzheimers Disease | 12 |
| Mass General Hospital | Biliary Tract Cancer (BTC), PDAC - Pancreatic Ductal Adenocarcinoma, AML | 12 |
| Ophthalmic Consultants of Boston | Macular Edema Secondary to Inflammation, Neovascular Age-related Macular Degeneration, Age-Related Macular Degeneration | 12 |
| Adams Clinical Boston | Major Depressive Disorder, Alcohol Use Disorder, Alzheimers Disease | 11 |
| Boston Childrens Hospital | CSTB-related Disease, Crohn's Disease, Cystic Fibrosis | 11 |
| Beth Israel Deaconess Medical Center (BIDMC) | Prostate Cancer, Advanced Melanoma, Early Rectal Cancer | 10 |
| Brigham and Women's Faulkner Hospital | Multimodal Analgesia, Opioid Consumption, Postoperative, Adverse Event | 8 |
Active & Upcoming Studies in Boston (2026)
Recruiting trials in Boston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (873 active studies)
- Early Intervention · Massachusetts General Hospital
- A Stepped Intervention for Coping With Dyspnea in Patients With Lung Cancer-Phase A (Open Pilot) · Massachusetts General Hospital
Neurology & pain (217 active studies)
- Mindfulness Therapy for Chronic Pain After Intimate Partner Violence · Brigham and Women's Hospital
- Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · Brigham and Women's Hospital
Cardiovascular (181 active studies)
- Computerized Decision Support to Prevent Stroke in Atrial Fibrillation · Brigham and Women's Hospital
- Boston Medical Center Ultrasound Decongestion Study in Heart Failure · Boston Medical Center
Diabetes & metabolic (98 active studies)
- Adiposity Distribution in Acute Respiratory Failure · Maurizio F. Cereda, MD
- Creating Linked Inpatient CGM for Kids · Boston Children's Hospital
Mental health & behavior (88 active studies)
- Whole Selves User Testing and Feasibility Study · Boston University
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
Pediatric (61 active studies)
- Clinician Practice Companion to Address Youth Substance Use · Massachusetts General Hospital
- Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease · EARLY_Phase 1 · Massachusetts General Hospital
HIV / STI (34 active studies)
- Intervention to Reduce Implicit Bias in Pharmacies · Massachusetts General Hospital
- Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP · Boston Children's Hospital
Eye & vision (30 active studies)
- Glaucoma Drop Aids Part 2 · Boston Medical Center
- Study of Remimazolam for Cataract Surgery · Phase 4 · Fred E, Shapiro
Vaccines (15 active studies)
- Sauna for Long Covid · Massachusetts General Hospital
- A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Boston
- Breast Cancer (65 active studies)
- Prostate Cancer (39 active studies)
- Heart Failure (34 active studies)
- Ovarian Cancer (34 active studies)
- Acute Myeloid Leukemia (32 active studies)
- Advanced Solid Tumor (31 active studies)
Leading research sponsors in Boston
- Massachusetts General Hospital
- Brigham and Women's Hospital
- Boston Children's Hospital
- Dana-Farber Cancer Institute
- Beth Israel Deaconess Medical Center
Frequently asked questions
How many paid clinical trials are currently recruiting in Boston?
There are approximately 2,876 recruiting clinical trials in Boston, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Boston pay participants?
Most recruiting trials in Boston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Boston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Boston?
The most common conditions under active study in Boston include Breast Cancer (65), Prostate Cancer (39), Heart Failure (34), Ovarian Cancer (34), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Boston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Boston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Boston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Boston?
Recruiting research sites in Boston include Massachusetts General Hospital, Brigham and Women's Hospital, Dana-Farber Cancer Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Boston right now?
The largest active categories in Boston are Cancer & tumors (873), Neurology & pain (217), Cardiovascular (181). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.