Paid Clinical Trials in Boston, MA

As of August 2026, 2,873 paid clinical trials are recruiting in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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2,484 clinical trials

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

for Parkinson's Disease (PD)

2 locations in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 18+

Code: NCT07455760·Recruiting·Listed Mar 2026

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Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Boston

Sponsor: David Avigan

Sex: All·Age: All ages

Code: NCT07374029·Phase 1·Recruiting·Listed Jan 2026

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An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism

for Autism Spectrum Disorder (ASD)

1 location in Boston

Sponsor: Northeastern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07421830·Recruiting·Listed Feb 2026

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CC-97540 in Patients With Antineutrophil Cytoplasmic Antibody-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

1 location in Boston

Sponsor: Marcela V. Maus, M.D.,Ph.D.

Sex: All·Age: 18+

Code: NCT07388277·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

for Cardiovascular Diseases

Sites in Boston +4 more locations

Sponsor: Fundación EPIC

Sex: All·Age: 18 - 85

Code: NCT07286578·Recruiting·Listed Dec 2025

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I-SLEPT: Integrated Sleep and Life Engagement Program for Transitions

for Sleep

1 location in Boston

Sponsor: VA Office of Research and Development

Sex: All·Age: 50+

Code: NCT07317336·Recruiting·Listed Jan 2026

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Cognitive Function and Affective Regulation in Meditators

for Cognitive Function and Affective Regulation

1 location in Boston

Sponsor: Balachundhar Subramaniam

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07546786·Recruiting·Listed Apr 2026

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Assessing MB-Spirit for Psychological Well-being

for Stress

2 locations in Boston

Sponsor: Sara W Lazar

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07325448·Recruiting·Listed Jan 2026

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MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

for Femoral Neck Fractures

Sites in Boston +18 more locations

Sponsor: University of Southern California

Sex: All·Age: 60+

Code: NCT07244211·Recruiting·Listed Nov 2025

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Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

for Renal Cell Carcinoma

3 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07397611·Phase 2·Recruiting·Listed Feb 2026

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The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

for Rheumatoid Arthritis (RA

3 locations in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 79

Code: NCT07315997·Recruiting·Listed Jan 2026

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

Sites in Boston +239 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025

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Pain Control for Cervical Ripening Balloon

for Labor Induction

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: Female·Age: 18+

Code: NCT07268118·Phase 2·Recruiting·Listed Dec 2025

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Dapagliflozin in Active Lupus Nephritis

for Lupus Nephritis (LN)

Drug: Dapagliflozin

2 locations in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 70

Code: NCT07323524·Phase 4·Recruiting·Listed Jan 2026

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The Safety and Efficacy of Roflumilast Foam in HS

for Hidradenitis Suppurativa (HS)

Drug: Roflumilast

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT07263230·Phase 2·Recruiting·Listed Dec 2025

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Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for Astrocytoma, IDH-Mutant, Grade 3

Drug: Vorasidenib

Sites in Boston +96 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 12+

Code: NCT07215910·Phase 3·Recruiting·Listed Oct 2025

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Statins to Prevent Cancer Associated Blood Clots

for Venous Thromboembolism

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07303816·Phase 4·Recruiting·Listed Dec 2025

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Tofersen in Non-SOD1 ALS

for ALS (Amyotrophic Lateral Sclerosis)

Sites in Boston +2 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07294144·Phase 2·Recruiting·Listed Dec 2025

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Body Acceptance After Baby Intervention

for Body Dissatisfaction

1 location in Boston

Sponsor: Northeastern University

Sex: Female·Age: 18+

Code: NCT07422571·Recruiting·Listed Feb 2026

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A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

for Epileptic Encephalopathy

Sites in Boston +4 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 2 - 12

Code: NCT07227857·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia

for Hypertensive Disorder of Pregnancy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07312227·Recruiting·Listed Dec 2025

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Zymfentra (Infliximab-dyyb) REal World Cohort STudy

for Ulcerative Colitis (UC)

Sites in Boston +10 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18+

Code: NCT07237516·Recruiting·Listed Nov 2025

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Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy

for Head Neck Cancer

Sites in Boston +5 more locations

Sponsor: University of Virginia

Sex: All·Age: 18 - 85

Code: NCT07405645·Recruiting·Listed Feb 2026

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Boston, Winchester +1098 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Boston, Brighton +633 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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Pulmonary Embolism and Right-to-Left Shunts

for Pulmonary Embolism (PE)

1 location in Boston

Sponsor: Tufts Medical Center

Sex: All·Age: 18+

Code: NCT07519876·Recruiting·Listed Apr 2026

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Boston, Brighton +913 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

Sites in Boston, Stoneham +777 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023

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Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for Intracranial Meningioma

Sites in Boston +445 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015

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mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

Sites in Boston, Brighton +630 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023

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ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Boston, Peabody +591 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025

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Promoting Recovery After Brain Injury Using Focused Ultrasound

for Consciousness Disorders

Sites in Boston & Cambridge

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 79

Code: NCT07277309·Recruiting·Listed Dec 2025

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

Sites in Boston, Stoneham +295 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020

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On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety

for Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07305740·Recruiting·Listed Dec 2025

Apply to this trial

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

for Malignancy

Sites in Boston +393 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: All ages

Code: NCT04242095·Recruiting·Listed Jan 2020

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Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

Sites in Boston, Stoneham +464 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016

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Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

for Adenocarcinoma of the Colon

Sites in Boston, Jamaica Plain +325 more locations

Sponsor: NRG Oncology

Sex: All·Age: 45 - 70

Code: NCT05080673·Recruiting·Listed Oct 2021

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Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia

for Hypertension

2 locations in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18 - 65

Code: NCT07238400·Phase 2·Recruiting·Listed Nov 2025

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

Sites in Boston, Peabody +525 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023

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A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

for Waldenstrom Macroglobulinemia

Drug: Venetoclax

Sites in Boston +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07231952·Phase 2·Recruiting·Listed Nov 2025

Apply to this trial