Paid Clinical Trials in Boston, MA

As of August 2026, 2,873 paid clinical trials are recruiting in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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Healthy volunteers only

2,484 clinical trials

Geriatric Thoracic Surgery Ambulation Challenge

for Thoracic Diseases

2 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 65+

Code: NCT04630496·Recruiting·Listed Nov 2020

Apply to this trial

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

for Cytomegalovirus Infections

1 location in Boston

Sponsor: Tufts Medical Center

Sex: All·Age: 18 - 75

Code: NCT05626530·Phase 4·Recruiting·Listed Nov 2022

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Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

for Burns Degree Third

Sites in Boston +3 more locations

Sponsor: XenoTherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06223269·Phase 3·Recruiting·Listed Jan 2024

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Impact of Thrombocytopenia and Platelet Transfusions on Neonatal Bleeding and Inflammation

for Neonatal Thrombocytopenia

2 locations in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 Days - 6 Months

Code: NCT03848923·Recruiting·Listed Feb 2019

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ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer

for Prostate Cancer

Sites in Boston +3 more locations

Sponsor: University of California, San Diego

Sex: Male·Age: 18+

Code: NCT06579417·Recruiting·Listed Aug 2024

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Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population

for Anxiety Disorders

1 location in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 18+

Code: NCT04895995·Recruiting·Listed May 2021

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A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT01890590·Recruiting·Listed Jul 2013

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Minority Barriers in Anesthesia

for Minority Barrier

1 location in Boston

Sponsor: Tufts Medical Center

Sex: All·Age: 25 - 75

Code: NCT04694339·Recruiting·Listed Jan 2021

Apply to this trial

Trazodone on OSA Endotypes

for Obstructive Sleep Apnea

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 21 - 70

Code: NCT06286189·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation

for Twin

1 location in Boston

Sponsor: Leiden University Medical Center

Sex: All·Age: 18 - 50

Code: NCT05952583·Recruiting·Listed Jul 2023

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Surgical Treatments for Postamputation Pain

for Residual Limb Pain

Sites in Boston +2 more locations

Sponsor: Prometei Pain Rehabilitation Center

Sex: All·Age: 18+

Code: NCT05009394·Recruiting·Listed Aug 2021

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Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot

for Tetralogy of Fallot

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT05236153·Recruiting·Listed Feb 2022

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Safety and Durability of Sirolimus for Treatment of LAM

for Lymphangioleiomyomatosis

Sites in Boston +7 more locations

Sponsor: University of Cincinnati

Sex: Female·Age: 18+

Code: NCT02432560·Recruiting·Listed May 2015

Apply to this trial

Effects of Ketosis on Brain Function in Patients With T1DM

for Type1diabetes

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 40

Code: NCT04219709·Recruiting·Listed Jan 2020

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Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

for Transthyretin Amyloidosis

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 65+

Code: NCT05577819·Recruiting·Listed Oct 2022

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Validating Gulf War Illness Blood Biomarkers

for Gulf War Syndrome

Sites in Boston +2 more locations

Sponsor: Roskamp Institute Inc.

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT05736146·Recruiting·Listed Feb 2023

Apply to this trial

Studying the Neuronal Basis of Human Social Cognition

for Neurosciences

Sites in Boston +1 more location

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05324579·Recruiting·Listed Apr 2022

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Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

for Thyroid Cancer

Sites in Boston +5 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12+

Code: NCT05668962·Phase 2·Recruiting·Listed Dec 2022

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Aspiration in Acute Respiratory Failure Survivors 2

for Dysphagia

Sites in Boston +4 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT05108896·Recruiting·Listed Nov 2021

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Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

for Comparing Manual and AI Patient Screening in Heart Failure

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06588452·Recruiting·Listed Sep 2024

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International Weight Control Registry

for Weight Loss

Sites in Boston +6 more locations

Sponsor: Tufts University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04907396·Recruiting·Listed May 2021

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TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)

for Cardiovascular Diseases

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 20+

Code: NCT00985049·Recruiting·Listed Sep 2009

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The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

for Sleep Deprivation

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT03767426·Recruiting·Listed Dec 2018

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Orphan Europe Carbaglu® Surveillance Protocol

for N-acetylglutamate Synthase (NAGS) Deficiency

Sites in Boston +2 more locations

Sponsor: Nicholas Ah Mew

Sex: All·Age: All ages

Code: NCT03409003·Recruiting·Listed Jan 2018

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International CDKL5 Clinical Research Network

for CDKL5

Sites in Boston +7 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 1 Month - 100

Code: NCT05558371·Recruiting·Listed Sep 2022

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A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn

for Hemangioma

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: Up to 3 Months·Accepts healthy volunteers

Code: NCT01873131·Recruiting·Listed Jun 2013

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VE416 for Treatment of Food Allergy

for Peanut Allergy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12 - 55

Code: NCT03936998·Phase 1, Phase 2·Recruiting·Listed May 2019

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A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

for Urologic Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05899361·Recruiting·Listed Jun 2023

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Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol

for Bladder Cancer

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 85

Code: NCT03216525·Phase 3·Recruiting·Listed Jul 2017

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Peripheral Neuroimmune Mechanisms of Hyperthermia

for Hyperthermia

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT05366270·Recruiting·Listed May 2022

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Pharmacological Activation of HMN for OSA Aim 2

for Obstructive Sleep Apnea

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 70

Code: NCT03858751·Phase 1, Phase 2·Recruiting·Listed Mar 2019

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The PROGRAM-study: Awake Mapping Versus Asleep Mapping Versus No Mapping for Glioblastoma Resections

for Glioblastoma

Sites in Boston +1 more location

Sponsor: Erasmus Medical Center

Sex: All·Age: 18 - 90

Code: NCT04708171·Recruiting·Listed Jan 2021

Apply to this trial

REtroperitoneal SArcoma Registry: an International Prospective Initiative

for Retroperitoneal Sarcoma

Sites in Boston +5 more locations

Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Sex: All·Age: 18+

Code: NCT03838718·Recruiting·Listed Feb 2019

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A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease

for Parkinson's Disease (PD)

Sites in Boston +2 more locations

Sponsor: Boston University Charles River Campus

Sex: All·Age: 40+

Code: NCT07705373·Recruiting·Listed Jul 15, 2026

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Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care

for Obesity & Overweight

2 locations in Boston

Sponsor: Tufts University

Sex: All·Age: 12 - 17

Code: NCT07717658·Recruiting·Listed Jul 21, 2026

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A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for Acute Migraine

Drug: Elismetrep

Sites in Boston, Waltham +112 more locations

Sponsor: Kallyope Inc.

Sex: All·Age: 18+

Code: NCT07674654·Phase 3·Recruiting·Listed Jun 29, 2026

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Addressing Cancer Care Equity With Social Determinants of Health Screening and Early Intervention

for Leukemia, Acute

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07671209·Recruiting·Listed Jun 26, 2026

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A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Boston +38 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662109·Phase 3·Recruiting·Listed Jun 23, 2026

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Cryoablation for Monomorphic Ventricular Tachycardia (VTS)

for Ventricular Tachycardia, Sustained

Sites in Boston +7 more locations

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT07650032·Recruiting·Listed Jun 2026

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The CARDIOPROTECT Trial

for Diffuse Large B-cell Lymphoma (DLBCL)

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT07654426·Phase 2·Recruiting·Listed Jun 17, 2026

Apply to this trial