Clinical Trials at University of Vermont Medical Center

As of August 2026, 71 paid clinical trials are recruiting at University of Vermont Medical Center, located at 111 COLCHESTER AVE, BURLINGTON, VT 05401-1473, phone (802) 847-9852 in Burlington, Vermont. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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72 clinical trials at University of Vermont Medical Center

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

Sites in Burlington +74 more locations

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting·Listed Dec 2022

Apply to this trial

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Burlington, Saint Johnsbury +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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Genomically Profiling, Collecting, Archiving and Distributing Hematologic Malignancy Specimens

for Leukemia

Sites in Burlington +5 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 30

Code: NCT04968834·Recruiting·Listed Jul 2021

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Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for Retroperitoneal Sarcoma

Sites in Burlington +96 more locations

Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All·Age: 18+

Code: NCT04031677·Phase 3·Recruiting·Listed Jul 2019

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SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

for Oropharyngeal Cancer

Sites in Burlington, Berlin Corners +21 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT05451004·Phase 3·Recruiting·Listed Jul 2022

Apply to this trial

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

for Glioblastoma

Sites in Burlington +10 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06934889·Phase 1·Recruiting·Listed Apr 2025

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Contingency Management to Improve Medication for Opioid Use Disorder Continuation After the Emergency Department

for Opioid Use Disorder

1 location in Burlington

Sponsor: University of Vermont

Sex: All·Age: 18+

Code: NCT07129902·Recruiting·Listed Aug 2025

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MOHs Surgery and Short-Course Radiation Therapy With Structured Follow-Up for Head & Neck Squamous Cell Skin Cancer

for Cutaneous Squamous Cell Carcinoma (CSCC)

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT06998342·Phase 2·Recruiting·Listed May 2025

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Avoiding Radiation Therapy Due to Intracranial Response to Chemotherapy, Targeted Therapy and/or Immuno-ONcology Therapy for Brain Metastases: Pilot Pragmatic Trial

for Brain Metastases, Adult

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT06974370·Phase 2·Recruiting·Listed May 2025

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Burlington, Berlin Corners +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

Sites in Burlington, Saint Johnsbury +378 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting·Listed Sep 2021

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Burlington, Saint Johnsbury +81 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

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Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

for Peritoneal Carcinomatosis

Sites in Burlington +1 more location

Sponsor: Prakash Pandalai

Sex: All·Age: 18+

Code: NCT04779554·Phase 2·Recruiting·Listed Mar 2021

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

Sites in Burlington, Berlin Corners +292 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting·Listed Sep 2018

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Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)

for Malnutrition

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT07072377·Recruiting·Listed Jul 2025

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Pyridostigmine for the Treatment of Constipation in Parkinson Disease

for Parkinson Disease

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT05603715·Phase 2·Recruiting·Listed Nov 2022

Apply to this trial

DOAC - Dosing Options in AntiCoagulation Prophylaxis

for Cancer

1 location in Burlington

Sponsor: University of Vermont

Sex: All·Age: 18+

Code: NCT07005024·Phase 3·Recruiting·Listed Jun 2025

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Fezolinetant for Treating Hot Flashes in Men With Prostate Cancer

for Prostate CA

1 location in Burlington

Sponsor: University of Vermont

Sex: Male·Age: 18+

Code: NCT06972875·Phase 2·Recruiting·Listed May 2025

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Burlington +67 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

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Hybrid Arc Palliative Radiation Therapy (HART): A Single Arm Phase II Trial

for Palliative Radiotherapy

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT06778408·Phase 2·Recruiting·Listed Jan 2025

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Venous Thromboembolism Prevention in Outpatients With Glioma

for Glioblastoma

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT05683808·Phase 2·Recruiting·Listed Jan 2023

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Multi-disciplinary Care for Brain Metastases

for Brain Metastases, Adult

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT06280300·Recruiting·Listed Feb 2024

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Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

Sites in Burlington +21 more locations

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting·Listed Dec 2025

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IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

for Nontuberculous Mycobacterium Infection

Sites in Burlington +9 more locations

Sponsor: Chris Goss

Sex: All·Age: 18+

Code: NCT04294043·Phase 1·Recruiting·Listed Mar 2020

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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for Cutaneous Melanoma, Stage II

Sites in Burlington +129 more locations

Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All·Age: 18+

Code: NCT03860883·Recruiting·Listed Mar 2019

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Accelerated Pulmonary Rehabilitation in the Preoperative Period

for Chronic Obstructive Pulmonary Disease

1 location in Burlington

Sponsor: University of Vermont

Sex: All·Age: 18+

Code: NCT06432972·Recruiting·Listed May 2024

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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

Sites in Burlington +54 more locations

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting·Listed Nov 2020

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International CIPN Assessment and Validation Study

for Chemotherapy-induced Peripheral Neuropathy

Sites in Burlington +7 more locations

Sponsor: University of Milano Bicocca

Sex: All·Age: 18+

Code: NCT04633655·Recruiting·Listed Nov 2020

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Improving Neurodevelopmental ouTcomes After Prenatal Cannabinoid in uTero Exposure

for Developmental Delay

Sites in Burlington +2 more locations

Sponsor: IDeA States Pediatric Clinical Trials Network

Sex: All·Age: Up to 7 Days·Accepts healthy volunteers

Code: NCT06423664·Recruiting·Listed May 2024

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Remote Smoking Cessation in Hospitalized Cardiac Patients

for Smoking Cessation

1 location in Burlington

Sponsor: University of Vermont Medical Center

Sex: All·Age: 18+

Code: NCT05738408·Recruiting·Listed Feb 2023

Apply to this trial

Pridopidine Phase 3 Study in Huntington's Disease

for Huntington Disease

Sites in Burlington +24 more locations

Sponsor: Prilenia

Sex: All·Age: 23 - 65

Code: NCT07609108·Phase 3·Recruiting·Listed May 2026

Apply to this trial