Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 28, 2026.

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5,286 clinical trials

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Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

for Extensive-stage Small-cell Lung Cancer

Drug: Atezolizumab

Sites in Los Angeles +2 more locations

Sponsor: Kamya Sankar

Sex: All·Age: All ages

Code: NCT05588388·Phase 2·Recruiting·Listed Oct 2022

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Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

for Breast Cancer

Sites in San Diego +8 more locations

Sponsor: Proton Collaborative Group

Sex: Female·Age: 50+

Code: NCT01766297·Phase 2·Recruiting·Listed Jan 2013

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Study of Cryoablation and Nirogacestat for Desmoid Tumor

for Desmoid Tumor

1 location in Palo Alto

Sponsor: Nam Bui

Sex: All·Age: 18+

Code: NCT05949099·Phase 2·Recruiting·Listed Jul 2023

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Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology

for Liver Cancer (Primary and Metastatic)

1 location in Palo Alto

Sponsor: Palo Alto Veterans Institute for Research

Sex: All·Age: 18+

Code: NCT07303725·Recruiting·Listed Dec 2025

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Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

for Spinal Cord Injury

Sites in Palo Alto, Long Beach +5 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06529094·Recruiting·Listed Jul 2024

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Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps

for Colorectal Carcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06376565·Recruiting·Listed Apr 2024

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Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for Differentiated Thyroid Cancer

Sites in San Francisco +4 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 99

Code: NCT05783323·Phase 2·Recruiting·Listed Mar 2023

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Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer

for Pancreatic Ductal Adenocarcinoma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06600906·Recruiting·Listed Sep 2024

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Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial

for Opioid Use Disorder

Sites in Arcata +2 more locations

Sponsor: University of New Mexico

Sex: All·Age: 18+

Code: NCT06565416·Recruiting·Listed Aug 2024

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Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

for Brain Concussion

Sites in San Diego +1 more location

Sponsor: United States Naval Medical Center, San Diego

Sex: All·Age: 18 - 60

Code: NCT06413173·Recruiting·Listed May 2024

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Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

for HIV Infections

Sites in San Francisco +3 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06665646·Phase 1·Recruiting·Listed Oct 2024

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Nab-Paclitaxel PIPAC in Combination With Paclitaxel and Ramucirumab for the Treatment of Stomach Cancer With Peritoneal Metastases

for Clinical Stage IVB Gastric Cancer AJCC v8

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06675136·Phase 1·Recruiting·Listed Nov 2024

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Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

for Stage IV NSCLC

Sites in Long Beach +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06671613·Recruiting·Listed Nov 2024

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Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

for Urethral Stricture, Male

Sites in San Francisco +1 more location

Sponsor: University of California, San Francisco

Sex: Male·Age: 18+

Code: NCT05300685·Phase 3·Recruiting·Listed Mar 2022

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Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 50+

Code: NCT06567717·Phase 2·Recruiting·Listed Aug 2024

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Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers

for Metastatic Pancreatic Adenocarcinoma

Sites in Duarte, Irvine +20 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06524973·Recruiting·Listed Jul 2024

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Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer

for Malignant Neoplasm

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT02280161·Recruiting·Listed Oct 2014

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Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations

for Chronic Disease

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT04160429·Recruiting·Listed Nov 2019

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Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

for Breast Carcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT05978128·Recruiting·Listed Aug 2023

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Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma

for Glioblastoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06090903·Recruiting·Listed Oct 2023

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Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

for Acute Myocardial Infarction

Sites in Los Angeles, San Francisco +11 more locations

Sponsor: Population Health Research Institute

Sex: All·Age: 18+

Code: NCT05701358·Recruiting·Listed Jan 2023

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HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants

for Hydrocephalus

Sites in Los Angeles +14 more locations

Sponsor: University of Utah

Sex: All·Age: 1 Day - 104 Weeks

Code: NCT04177914·Phase 3·Recruiting·Listed Nov 2019

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Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury

for Spinal Cord Injuries

2 locations in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 75

Code: NCT04883463·Recruiting·Listed May 2021

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AAT for Alcohol Use Disorder in Veterans

for Alcohol Use Disorder

1 location in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 65

Code: NCT05372029·Recruiting·Listed May 2022

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Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI

for Suicidal Ideation

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 70

Code: NCT05377177·Recruiting·Listed May 2022

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A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

for Esophageal Adenocarcinoma

Sites in Palo Alto +6 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05563766·Phase 2·Recruiting·Listed Oct 2022

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Electrical Stimulation for Vision Neuroenhancement in Glaucoma

for Glaucoma

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06685211·Recruiting·Listed Nov 2024

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Study for Remote Investigation of Evaporative Dry Eye Disease

for Evaporative Loss Dry Eye Disease

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06976515·Recruiting·Listed May 2025

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The Mechanism Versus PPI Trial

for Laryngopharyngeal Reflux

1 location in San Deigo

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 89

Code: NCT06999577·Phase 4·Recruiting·Listed May 2025

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Ultra-hypofractionated Whole Breast Irradiation With Lumpectomy Cavity Boost for the Treatment of Stage I-III Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte, Irvine +5 more locations

Sponsor: City of Hope Medical Center

Sex: Female·Age: 40+

Code: NCT06954831·Phase 2·Recruiting·Listed May 2025

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A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis

for Multiple Sclerosis

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 65

Code: NCT06138132·Phase 1·Recruiting·Listed Nov 2023

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Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

for Surgery-Complications

Sites in San Francisco, Stanford +18 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05991453·Recruiting·Listed Aug 2023

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Stress Hydrocortisone In Pediatric Septic Shock

for Septic Shock

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: Jerry Zimmerman

Sex: All·Age: 1 Month - 17

Code: NCT03401398·Phase 3·Recruiting·Listed Jan 2018

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Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

for Relapsed Adult AML

Sites in Stanford +19 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT05237258·Recruiting·Listed Feb 2022

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Vancomycin Reduction Practices (VRP) in the NICU

for Antibiotic Stewardship

Sites in San Francisco, Walnut Creek +11 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18+

Code: NCT06772675·Recruiting·Listed Jan 2025

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Feasibility of HPV Testing With Mail-delivered Sample Collection Kits

for HPV Infection

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 35+

Code: NCT07087145·Recruiting·Listed Jul 2025

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THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy

for Abuse, Drug

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 21 - 55·Accepts healthy volunteers

Code: NCT06859710·Phase 1·Recruiting·Listed Mar 2025

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APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

for Overactive Bladder (OAB)

Sites in Palo Alto +8 more locations

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 22+

Code: NCT06797245·Recruiting·Listed Jan 2025

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Implementation of Team Clinic for Type 2 Diabetes (TCT2)

for Type 2 Diabetes

Sites in Los Angeles & San Francisco

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 12 - 18

Code: NCT06923046·Recruiting·Listed Apr 2025

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Prostate Cancer Postoperative Stereotactic Body Radiotherapy With Adaptive Technology for Minimizing Toxicity

for Prostate Cancer (CRPC)

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male·Age: 18+

Code: NCT07077239·Recruiting·Listed Jul 2025

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