Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 28, 2026.

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5,286 clinical trials

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A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

for Postoperative Delirium

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT05010148·Phase 3·Recruiting·Listed Aug 2021

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Effect of Ketamine on Intraoperative Motor Evoked Potentials

for Spine Fusion

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 100

Code: NCT06140927·Phase 3·Recruiting·Listed Nov 2023

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Feasibility of Endovascular Repair Of Ascending Aortic Pathologies

for Aortic Dissection

Sites in Long Beach & Torrance

Sponsor: Rodney A. White, MD

Sex: All·Age: 18+

Code: NCT02201589·Recruiting·Listed Jul 2014

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Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)

for Multiple Sclerosis

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06940323·Recruiting·Listed Apr 2025

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Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

for Psoriasis

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: Female·Age: All ages

Code: NCT02103361·Recruiting·Listed Apr 2014

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Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure

for Cardiotoxicity

1 location in San Diego

Sponsor: Hari Narayan

Sex: All·Age: 13 - 39

Code: NCT04262830·Recruiting·Listed Feb 2020

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Monitoring Pregnancy and Infant Outcomes Following Tralokinumab Exposure During Pregnancy in the US and Canada - PROTECT

for Atopic Dermatitis

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: Female·Age: All ages

Code: NCT05938478·Recruiting·Listed Jul 2023

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Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block

for Heart Block Complete

Sites in San Francisco +11 more locations

Sponsor: The Hospital for Sick Children

Sex: Female·Age: 16 - 50

Code: NCT04559425·Recruiting·Listed Sep 2020

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Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis

for Dermatomyositis

Sites in Palo Alto & Stanford

Sponsor: Stanford University

Sex: All·Age: 25 - 72

Code: NCT06298019·Phase 1·Recruiting·Listed Mar 2024

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Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics

for Chronic Daily Headache

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03231241·Recruiting·Listed Jul 2017

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Researchers At UC San Diego Are Learning About the Benefits of Human Milk and How It Influences Infant and Child Health

for Breastfeeding

1 location in San Diego

Sponsor: University of California, San Diego

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05553743·Recruiting·Listed Sep 2022

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Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

for Diabetes Mellitus, Type 2

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 35 - 65·Accepts healthy volunteers

Code: NCT05165706·Recruiting·Listed Dec 2021

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Levothyroxine Supplementation for Heart Transplant Recipients

for Heart Transplant Failure

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06428097·Phase 1·Recruiting·Listed May 2024

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Pilot Study of Pancreatic Cancer Screening

for Pancreatic Carcinoma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05058846·Recruiting·Listed Sep 2021

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Intraamniotic Administrations of ER004 to Male Subjects With X-linked Hypohidrotic Ectodermal Dysplasia

for X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED)

Sites in Los Angeles +1 more location

Sponsor: EspeRare Foundation

Sex: Female·Age: 18+

Code: NCT04980638·Phase 2·Recruiting·Listed Jul 2021

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Massed Prolonged Exposure for PTSD in Substance Use Treatment

for Stress Disorders, Post-Traumatic

Sites in San Diego +3 more locations

Sponsor: Veterans Medical Research Foundation

Sex: All·Age: 18+

Code: NCT06296186·Recruiting·Listed Mar 2024

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Down Syndrome Obstructive Sleep Apnea

for Down Syndrome

Sites in Los Angeles +6 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 5 - 18

Code: NCT06043440·Phase 2·Recruiting·Listed Sep 2023

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Limiting AAA With Metformin (LIMIT) Trial

for Abdominal Aortic Aneurysm

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 50 - 95

Code: NCT04500756·Phase 2·Recruiting·Listed Aug 2020

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First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia

for Alzheimer Disease

1 location in San Francisco

Sponsor: David Wilson

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05374278·Phase 1, Phase 2·Recruiting·Listed May 2022

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Effect of Electro-Acupuncture on Blood Pressure

for Hypertension

Sites in Orange & Irvine

Sponsor: University of California, Irvine

Sex: All·Age: 18 - 85

Code: NCT00932139·Recruiting·Listed Jul 2009

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International Registry of Patients With Alpha Thalassemia

for Alpha-Thalassemia

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT04872179·Recruiting·Listed May 2021

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Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised Immunity

for Adenovirus

2 locations in Palo Alto

Sponsor: Jessie L. Alexander

Sex: All·Age: 1 Month - 65

Code: NCT06909110·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer

for Prostate Cancer

Sites in San Francisco, San Diego +2 more locations

Sponsor: University of California, San Diego

Sex: Male·Age: 18+

Code: NCT06579417·Recruiting·Listed Aug 2024

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Blood Changes After Exercise in Restless Legs Syndrome

for Restless Legs Syndrome

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06481176·Recruiting·Listed Jul 2024

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Decreasing Emergence Agitation With Personalized Music

for Surgical Procedure, Unspecified

Sites in Stanford +1 more location

Sponsor: Stanford University

Sex: All·Age: 3 - 9

Code: NCT05044832·Recruiting·Listed Sep 2021

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Comparing Operative vs Non Operative Treatment for Pilonidal Disease

for Pilonidal Disease

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 8+

Code: NCT05439291·Recruiting·Listed Jun 2022

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HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

for Heart Failure

Sites in La Jolla +11 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18 - 100

Code: NCT06425848·Recruiting·Listed May 2024

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Effect of Dupilumab on the Muscle Function of the Esophagus (food Pipe) in Participants with Eosinophilic Esophagitis (EoE)

for Eosinophilic Esophagitis (EoE)

Drug: Dupilumab

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 22+

Code: NCT06665971·Phase 4·Recruiting·Listed Oct 2024

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Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism

for Autism Spectrum Disorder (ASD)

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 6 - 12

Code: NCT06627205·Recruiting·Listed Oct 2024

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Safer Aging With Diabetes Monitoring

for Diabetes Mellitus, Type 2

Sites in Fremont, San Jose +2 more locations

Sponsor: Kaiser Permanente

Sex: All·Age: 75+

Code: NCT06296485·Recruiting·Listed Mar 2024

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Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC

for HNSCC

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18 - 79

Code: NCT06693323·Phase 2·Recruiting·Listed Nov 2024

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Effects of Acupuncture on Symptoms of Stable Angina

for Angina, Stable

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 21+

Code: NCT06311461·Recruiting·Listed Mar 2024

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International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

for Squamous Cell Carcinoma of the Penis, Usual Type

Sites in Los Angeles +5 more locations

Sponsor: Institute of Cancer Research, United Kingdom

Sex: Male·Age: 18+

Code: NCT02305654·Phase 3·Recruiting·Listed Dec 2014

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Natural History Study of Patients with HPDL Mutations

for Mitochondrial Encephalomyopathies

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: All ages

Code: NCT05848271·Recruiting·Listed May 2023

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Effect of Fetal Aortic Valvuloplasty on Outcomes

for Congenital Heart Disease

Sites in San Francisco +1 more location

Sponsor: Queen Silvia Children's Hospital, Gothenburg, Sweden

Sex: All·Age: 23 Weeks - 31 Weeks

Code: NCT05386173·Recruiting·Listed May 2022

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Near Infrared Spectroscopy (NIRS) for Assessment of Depression

for Major Depressive Disorder

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04061148·Recruiting·Listed Aug 2019

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Partner Navigation Intervention for Hepatitis C Treatment Among Young People Who Inject Drugs

for Hepatitis C

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06179498·Recruiting·Listed Dec 2023

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Recording of Intraoperative Spinal Cord Stimulation and Monitoring

for Cervical Stenosis

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT05356286·Recruiting·Listed May 2022

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Family Intervention to Prevent Childhood Obesity

for Childhood Obesity

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT05606731·Recruiting·Listed Nov 2022

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Spinal Cord Stimulation to Shorten Ventilator Dependence in ARDS Patients

for Respiratory Distress Syndrome

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT05928052·Recruiting·Listed Jul 2023

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