Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 29, 2026.

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5,286 clinical trials

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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Los Alamitos, Lomita +22 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662044·Phase 3·Recruiting·Listed Jun 23, 2026

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A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Los Angeles, Bakersfield +37 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662109·Phase 3·Recruiting·Listed Jun 23, 2026

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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Sacramento, Concord +26 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662135·Phase 3·Recruiting·Listed Jun 23, 2026

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A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Semaglutide

Sites in Sacramento, Long Beach +61 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662213·Phase 3·Recruiting·Listed Jun 23, 2026

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A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer

for ER-Positive HER2-Negative Breast Cancer

Drug: Camizestrant

Sites in Palo Alto, Duarte +10 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07647328·Phase 3·Recruiting·Listed Jun 15, 2026

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A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Los Angeles, Sacramento +33 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07652658·Phase 2·Recruiting·Listed Jun 17, 2026

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A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Glendale, Whittier +28 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07623161·Phase 3·Recruiting·Listed Jun 3, 2026

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Trial to Test the Efficacy of Using Magnetic Fields to Stimulate the Back to Treat Chronic Lower Back Pain.

for Lower Back Pain Chronic

1 location in Edwards Air Force Base

Sponsor: Joe X. Zhang

Sex: All·Age: 18 - 64

Code: NCT07652944·Recruiting·Listed Jun 17, 2026

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AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

for Metastatic Castration-resistant Prostate Cancer

Sites in San Francisco, Duarte +22 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT07611110·Phase 3·Recruiting·Listed May 2026

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A Study of LY3439539 in Participants With Alzheimer's Disease

for Alzheimer Disease

1 location in Irvine

Sponsor: Eli Lilly and Company

Sex: All·Age: 50 - 85

Code: NCT07598370·Phase 1·Recruiting·Listed May 2026

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A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies

for Type 2 Diabetes

Sites in Lincoln +7 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07606066·Recruiting·Listed May 2026

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A Study to Assess the Safety, Tolerability and Efficacy of ION775

for Hypertriglyceridemia

Sites in Lincoln +14 more locations

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07604974·Phase 2·Recruiting·Listed May 2026

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Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Encino, South Pasadena +8 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 99

Code: NCT07590934·Phase 1, Phase 2·Recruiting·Listed May 2026

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A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease

for Primary Membranous Nephropathy

Sites in Los Angeles +5 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT07571746·Phase 2·Recruiting·Listed May 2026

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TEAPOT Study Multisite

for Hemorrhage, Surgical

Sites in Davis +2 more locations

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 2 - 17

Code: NCT07565753·EARLY_Phase 1·Recruiting·Listed May 2026

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Effects of Accelerated rTMS on Cognitive Function

for Cognitive Decline

1 location in San Francisco

Sponsor: San Francisco Neurology and Sleep Center

Sex: All·Age: 50 - 90

Code: NCT07547319·Recruiting·Listed Apr 2026

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer (epNEC)

Drug: Obrixtamig

Sites in San Francisco, Palo Alto +19 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Recruiting·Listed Apr 2026

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A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234

for Hepatic Impairment

Sites in Rialto +3 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07546760·Phase 1·Recruiting·Listed Apr 2026

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A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant in Participants With ER+/HER2- Early Breast Cancer Who Are Intolerant to Adjuvant Aromatase Inhibitor Therapy (novERA Breast Cancer)

for Early Breast Cancer

Drug: Giredestrant

1 location in Fountain Valley

Sponsor: Genentech, Inc.

Sex: Female·Age: 18+

Code: NCT07541079·Phase 3·Recruiting·Listed Apr 2026

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A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression

for Ovarian Cancer

Sites in San Francisco, Torrance +9 more locations

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT07546500·Phase 3·Recruiting·Listed Apr 2026

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A Phase 2 Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma

for Severe Asthma

Drug: Frevecitinib

Sites in Lancaster, San Jose +12 more locations

Sponsor: Kinaset Therapeutics Inc

Sex: All·Age: 18 - 75

Code: NCT07532265·Phase 2·Recruiting·Listed Apr 2026

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A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

for Irritable Bowel Syndrome

Sites in Los Angeles, San Diego +108 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 80

Code: NCT07519395·Phase 2·Recruiting·Listed Apr 2026

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ALTO-207 in Adults With Treatment-resistant Depression (TRD)

for Treatment-resistant Depression (TRD)

Sites in San Diego, Palo Alto +36 more locations

Sponsor: Alto Neuroscience

Sex: All·Age: 18 - 75

Code: NCT07553637·Phase 2·Recruiting·Listed Apr 2026

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A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 2

for Narcolepsy Type 2

Drug: ALKS 2680

Sites in Los Angeles +16 more locations

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT07502443·Phase 3·Recruiting·Listed Mar 2026

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A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

for Healthy Participants

Sites in Glendale +1 more location

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07511205·Phase 1·Recruiting·Listed Apr 2026

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Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

for Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms

Drug: Solriamfetol

Sites in Los Angeles, San Diego +38 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT07484217·Phase 3·Recruiting·Listed Mar 2026

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Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa

for Epidermolysis Bullosa (EB)

1 location in Rancho Santa Margarita

Sponsor: Paradigm Therapeutics

Sex: All·Age: 28 Days - 12

Code: NCT07482787·Phase 3·Recruiting·Listed Mar 2026

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Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

Sites in Los Angeles, San Diego +22 more locations

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07474792·Phase 2·Recruiting·Listed Mar 2026

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A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma

for Asthma

Sites in San Diego, Long Beach +9 more locations

Sponsor: AstraZeneca

Sex: All·Age: 4 - 11

Code: NCT07525375·Phase 2·Recruiting·Listed Apr 2026

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A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)

for Pulmonary Arterial Hypertension

Sites in Santa Barbara +1 more location

Sponsor: Insmed Incorporated

Sex: All·Age: 18 - 75

Code: NCT07481981·Phase 3·Recruiting·Listed Mar 2026

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A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

for Extensive-stage Small-cell Lung Cancer

Drug: Lurbinectedin

Sites in Los Angeles +3 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07459634·Phase 2·Recruiting·Listed Mar 2026

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Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer

for Limited Stage Small Cell Lung Cancer

1 location in Oakland

Sponsor: Pharmacosmos A/S

Sex: All·Age: 18+

Code: NCT07473128·Phase 3·Recruiting·Listed Mar 2026

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A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults

for Influenza, Human+COVID-19

Sites in San Diego, Fair Oaks +10 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 65 - 85

Code: NCT07464314·Phase 1·Recruiting·Listed Mar 2026

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A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1

for Narcolepsy Type 1

Drug: ALKS 2680

Sites in Los Angeles +17 more locations

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT07455383·Phase 3·Recruiting·Listed Mar 2026

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A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma

for Asthma

Drug: Depemokimab

Sites in Newport Beach +7 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 12+

Code: NCT07456033·Phase 3·Recruiting·Listed Mar 2026

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An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for Plaque Psoriasis

Sites in Los Angeles, San Diego +14 more locations

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07449702·Phase 2·Recruiting·Listed Mar 2026

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Ceribell Delirium Monitor Outcomes Pilot Study

for Delirium in the Intensive Care Unit

Sites in Irvine +1 more location

Sponsor: Ceribell Inc.

Sex: All·Age: 18+

Code: NCT07449416·Recruiting·Listed Mar 2026

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A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sites in La Jolla, San Leandro +25 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 70

Code: NCT07430306·Phase 3·Recruiting·Listed Feb 2026

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

Sites in La Jolla, Duarte +70 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting·Listed Feb 2026

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A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age

for Measles

Sites in Walnut Creek +16 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 15 Months - 6·Accepts healthy volunteers

Code: NCT07406360·Phase 3·Recruiting·Listed Feb 2026

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