Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 30, 2026.

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5,295 clinical trials

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A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

Sites in San Diego, Palo Alto +10 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06879041·Phase 1·Recruiting·Listed Mar 2025

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A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

Sites in San Diego, La Jolla +25 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06417814·Phase 3·Recruiting·Listed May 2024

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Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for Gastric Cancer

Sites in Los Angeles +3 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05702229·Phase 2·Recruiting·Listed Jan 2023

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Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

for Eosinophilic Asthma

Sites in Newport Beach, Pasadena +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12 - 75

Code: NCT06750289·Phase 3·Recruiting·Listed Dec 2024

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Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

for Hereditary Angioedema (HAE)

Sites in San Diego, Santa Monica +10 more locations

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 12+

Code: NCT06679881·Phase 3·Recruiting·Listed Nov 2024

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Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

for Arrhythmia

Sites in La Jolla, Stanford +83 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT00271180·Recruiting·Listed Dec 2005

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Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Drug: Osimertinib

Sites in Los Angeles, San Diego +26 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06350097·Phase 3·Recruiting·Listed Apr 2024

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Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention

for Suicidal Thoughts and Behaviors

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 65

Code: NCT06809348·Recruiting·Listed Feb 2025

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ALXN2420 Versus Placebo in Combination With Somatostatin Analogs in Participants With Acromegaly

for Acromegaly

Sites in Los Angeles, Torrance +6 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18 - 80

Code: NCT07037420·Phase 2·Recruiting·Listed Jun 2025

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Optimizing the Timing of rTMS to Enhance the Administration of Insomnia Treatment

for Insomnia

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 25 - 45

Code: NCT06656533·Recruiting·Listed Oct 2024

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A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

for Multiple Myeloma

Drug: Belantamab mafodotin

Sites in Beverly Hills, Pasadena +28 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06679101·Phase 3·Recruiting·Listed Nov 2024

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A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA

for Growth Hormone Deficiency

Sites in San Francisco, Sacramento +25 more locations

Sponsor: Ascendis Pharma Endocrinology Division A/S

Sex: All·Age: All ages

Code: NCT05820672·Recruiting·Listed Apr 2023

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Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC

for Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Sites in Orange +3 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT04686305·Phase 1·Recruiting·Listed Dec 2020

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First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

for Hepatocellular Carcinoma

Sites in Los Angeles, La Jolla +4 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06795022·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

for Liver Diseases, Alcoholic

Sites in Los Angeles, Davis +24 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 70

Code: NCT06613698·Phase 2·Recruiting·Listed Sep 2024

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Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

for Hypertension

Sites in Walnut Creek, Chula Vista +26 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07090161·Phase 2·Recruiting·Listed Jul 2025

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Observation of Wheeled Device Use After TKA

for Total Knee Arthroplasty

1 location in Redwood City

Sponsor: Stanford University

Sex: All·Age: 18 - 99

Code: NCT06080152·Recruiting·Listed Oct 2023

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A Study of D3L-001 as Monotherapy in Subjects With HER2-Positive Advanced Solid Tumors

for HER-2 Positive Advanced Solid Tumors

Sites in Stanford +2 more locations

Sponsor: D3 Bio (Wuxi) Co., Ltd

Sex: All·Age: 18+

Code: NCT05957536·Phase 1·Recruiting·Listed Jul 2023

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A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for Solid Tumor

Sites in Palo Alto, La Jolla +15 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06384807·Phase 1, Phase 2·Recruiting·Listed Apr 2024

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A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function

for Semen Quality

Sites in Pomona, North Hollywood +2 more locations

Sponsor: ReproNovo Aps

Sex: Male·Age: 18 - 49

Code: NCT06993155·Phase 2·Recruiting·Listed May 2025

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A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

for Lung Diseases, Interstitial

Sites in Los Angeles, San Francisco +14 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06572384·Phase 3·Recruiting·Listed Aug 2024

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A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)

for Chronic Hepatitis B Infection

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: Aligos Therapeutics

Sex: All·Age: 18 - 65

Code: NCT06963710·Phase 2·Recruiting·Listed May 2025

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Optimizing Reperfusion to Improve Outcomes and Neurologic Function

for Acute Ischemic Stroke

Sites in Sacramento, Long Beach +15 more locations

Sponsor: Corxel Pharmaceuticals

Sex: All·Age: 18 - 90

Code: NCT06990867·Phase 2, Phase 3·Recruiting·Listed May 2025

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A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors

for Melanoma (Skin)

Sites in La Jolla +4 more locations

Sponsor: Hummingbird Bioscience

Sex: All·Age: 18+

Code: NCT06956690·Phase 1, Phase 2·Recruiting·Listed May 2025

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Study of AZD0754 in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Duarte +12 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 130

Code: NCT06267729·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

for Acute Respiratory Distress Syndrome

Sites in Sacramento, Irvine +30 more locations

Sponsor: Direct Biologics, LLC

Sex: All·Age: 18 - 75

Code: NCT05354141·Phase 3·Recruiting·Listed Apr 2022

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Safety and Efficacy of VDPHL01 in Females With Androgenetic Alopecia (AGA)

for Androgenetic Alopecia (AGA)

Sites in Santa Monica, Fremont +68 more locations

Sponsor: Veradermics, Inc.

Sex: Female·Age: 18 - 65

Code: NCT07146022·Phase 3·Recruiting·Listed Aug 2025

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A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

for Growth Hormone Deficiency

Sites in San Francisco, Sacramento +25 more locations

Sponsor: Ascendis Pharma Endocrinology Division A/S

Sex: All·Age: 1 - 18

Code: NCT05775523·Recruiting·Listed Mar 2023

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An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

for Dry Eye

Sites in Newport Beach +4 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07179055·Phase 2·Recruiting·Listed Sep 2025

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Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC

for Non-infected Venous Leg Ulcer

Sites in San Francisco, Torrance +19 more locations

Sponsor: BioStem Technologies

Sex: All·Age: 18+

Code: NCT06811909·Recruiting·Listed Feb 2025

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Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

for Colonic Neoplasms

Drug: Dostarlimab

Sites in Los Angeles +26 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT05855200·Phase 3·Recruiting·Listed May 2023

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Randomized Withdrawal Study in Patients With Schizophrenia

for Schizophrenia

Sites in San Diego, Walnut Creek +20 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06961968·Phase 3·Recruiting·Listed May 2025

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A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

for Systemic Sclerosis Associated Interstitial Lung Disease

Sites in Los Angeles, Upland +22 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT05878717·Phase 2, Phase 3·Recruiting·Listed May 2023

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Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sites in Orange, Glendale +26 more locations

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18+

Code: NCT06480383·Phase 2·Recruiting·Listed Jun 2024

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Focused Orticumab Research for Treating Inflammation in Coronary Arteries

for Acute Coronary Syndromes

Drug: Orticumab

Sites in Los Angeles, Torrance +5 more locations

Sponsor: Abcentra

Sex: All·Age: 18+

Code: NCT06927739·Phase 2·Recruiting·Listed Apr 2025

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Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Sites in Los Angeles, Sacramento +20 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT06947993·Phase 2·Recruiting·Listed Apr 2025

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Virtual 1-Session Spanish "Empowered Relief" Group Intervention for Chronic Pain

for Chronic Pain

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT04546685·Recruiting·Listed Sep 2020

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Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

for Major Depressive Disorder (MDD)

Sites in Orange, Walnut Creek +17 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06830044·Phase 3·Recruiting·Listed Feb 2025

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Study of ALTO-300 in MDD

for Major Depressive Disorder

Sites in Los Angeles, Glendale +36 more locations

Sponsor: Alto Neuroscience

Sex: All·Age: 18 - 70

Code: NCT05922878·Phase 2·Recruiting·Listed Jun 2023

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Post-Authorization Safety Study for Assessment of Pregnancy Outcomes in Patients Treated With Mayzent

for Multiple Sclerosis

1 location in La Jolla

Sponsor: Novartis Pharmaceuticals

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT04933552·Recruiting·Listed Jun 2021

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