Paid Clinical Trials in California

California has 6,389 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

for Solid Tumours

Drug: Zongertinib

Sites in Los Angeles, La Jolla +18 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06581432·Phase 2·Recruiting·Listed Sep 2024

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Abbott Cephea Mitral Valve Disease Registry

for Mitral Regurgitation

Sites in Thousand Oaks +22 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07069673·Recruiting·Listed Jul 2025

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Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

Sites in Palo Alto +15 more locations

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting·Listed Aug 2025

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A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

for Colorectal Cancer

Drug: Bevacizumab

Sites in Los Angeles +10 more locations

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT06948448·Phase 2·Recruiting·Listed Apr 2025

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Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

for Schizophrenia

Drug: KarXT

Sites in Orange, San Jose +15 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07101094·Recruiting·Listed Aug 2025

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BoxX-NoAF Clinical Trial

for Post Operative Atrial Fibrillation

Sites in San Diego +23 more locations

Sponsor: AtriCure, Inc.

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06989775·Recruiting·Listed May 2025

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Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for Non-small Cell Lung Cancer

Sites in Orange, Newport Beach +20 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06765109·Phase 3·Recruiting·Listed Jan 2025

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A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome

for Lipidemia

Drug: Obicetrapib

Sites in La Jolla +19 more locations

Sponsor: NewAmsterdam Pharma

Sex: All·Age: 18+

Code: NCT07219602·Phase 3·Recruiting·Listed Oct 2025

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A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

for Colorectal Neoplasms

Sites in Duarte +20 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT06131840·Phase 1·Recruiting·Listed Nov 2023

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A Study of PHST001 in Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Los Angeles, Palo Alto +18 more locations

Sponsor: Pheast Therapeutics

Sex: All·Age: 18+

Code: NCT06840886·Phase 1·Recruiting·Listed Feb 2025

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A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for Chronic Lymphocytic Leukemia

Drug: Ibrutinib

Sites in Palo Alto, Anaheim +10 more locations

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05254743·Phase 3·Recruiting·Listed Feb 2022

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A Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid Tumors

for Non-small Cell Lung Cancer

Sites in Los Angeles, Glendale +10 more locations

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18 - 85

Code: NCT07160335·Phase 1·Recruiting·Listed Sep 2025

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A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP

for Chronic Inflammatory Demyelinating Polyneuropathy

Sites in Rancho Mirage +8 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07091630·Phase 3·Recruiting·Listed Jul 2025

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A Study of LY4175408 in Participants With Advanced Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY4175408

Sites in Stanford +14 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07046923·Phase 1·Recruiting·Listed Jul 2025

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A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

for Human Immunodeficiency Virus (HIV)

Sites in Los Angeles, San Francisco +21 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07044297·Phase 3·Recruiting·Listed Jun 2025

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A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema

for Macular Edema

Sites in San Francisco, Pasadena +21 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06962839·Phase 2·Recruiting·Listed May 2025

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A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Sotorasib

Sites in Santa Barbara +18 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT05920356·Phase 3·Recruiting·Listed Jun 2023

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Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

for Small Cell Lung Cancer Metastatic or Locally Advanced

Sites in Los Angeles, San Francisco +18 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT07080242·Phase 1·Recruiting·Listed Jul 2025

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A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

for Solid Tumors

Drug: INCB161734

Sites in Palo Alto, Santa Monica +11 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06179160·Phase 1·Recruiting·Listed Dec 2023

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A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

for Obesity

Sites in Los Angeles, Orange +49 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT06672549·Phase 3·Recruiting·Listed Nov 2024

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A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for Lymphoma

Drug: Glofitamab

Sites in Duarte, Santa Monica +13 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06084936·Phase 3·Recruiting·Listed Oct 2023

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for Metastatic Solid Tumor

Drug: LY4052031

Sites in Los Angeles, La Jolla +18 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06465069·Phase 1·Recruiting·Listed Jun 2024

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A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for Metastatic Solid Tumor

Sites in Duarte +17 more locations

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06657144·Phase 1·Recruiting·Listed Oct 2024

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Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

for Biliary Tract Cancer

Sites in Duarte +12 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06282575·Phase 3·Recruiting·Listed Feb 2024

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Sacral Neuromodulation for Male Overactive Bladder (MOAB)

for Overactive Bladder

Sites in Mountain View, Murrieta +17 more locations

Sponsor: Axonics, Inc.

Sex: Male·Age: 18+

Code: NCT06511141·Recruiting·Listed Jul 2024

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Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Sites in Los Angeles, Santa Rosa +23 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06899126·Phase 3·Recruiting·Listed Mar 2025

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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

Sites in Los Angeles, Stanford +22 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting·Listed Oct 2024

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Study of COYA 302 for the Treatment of ALS

for Amyotrophic Lateral Sclerosis (ALS)

Sites in Los Angeles, San Francisco +19 more locations

Sponsor: Coya Therapeutics

Sex: All·Age: 18 - 80

Code: NCT07161999·Phase 2·Recruiting·Listed Sep 2025

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Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

for Systemic Lupus Erythematosus

Drug: Ianalumab

Sites in Burbank, La Palma +17 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT06133972·Phase 3·Recruiting·Listed Nov 2023

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A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

for Multiple Sclerosis (MS) Primary Progressive

Sites in West Hollywood +13 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07067463·Phase 3·Recruiting·Listed Jul 2025

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BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)

for Solid Tumor Cancer

Sites in San Francisco +10 more locations

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07193511·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

Sites in Los Angeles +21 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06919965·Phase 3·Recruiting·Listed Apr 2025

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Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors

for Gastric Adenocarcinoma

Sites in Los Angeles +16 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT07021066·Phase 1·Recruiting·Listed Jun 2025

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Pivotal Study of the Velocity™ pAVF System

for Chronic Kidney Disease

Sites in Riverside, Concord +10 more locations

Sponsor: Venova Medical

Sex: All·Age: 18 - 80

Code: NCT07153939·Recruiting·Listed Sep 2025

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An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

for Lennox Gastaut Syndrome

Sites in Orange +11 more locations

Sponsor: Epygenix

Sex: All·Age: 2 - 55

Code: NCT05066217·Phase 3·Recruiting·Listed Oct 2021

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Onyx™ Liquid Embolic IDE Clinical Study

for Peripheral Arterial Hemorrhage

Sites in Palo Alto, Irvine +15 more locations

Sponsor: Medtronic Endovascular

Sex: All·Age: 22+

Code: NCT06742801·Recruiting·Listed Dec 2024

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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for Uncontrolled Hypertension

Sites in San Jose, West Hills +20 more locations

Sponsor: Retension Pharmaceuticals. Inc.

Sex: All·Age: 18 - 70

Code: NCT07142356·Phase 2·Recruiting·Listed Aug 2025

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A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for Metastatic Colorectal Cancer

Drug: Bevacizumab

Sites in Duarte, Santa Monica +12 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06820463·Phase 2·Recruiting·Listed Feb 2025

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A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies

for NSCLC

Drug: EP0031

Sites in Los Angeles, Stanford +13 more locations

Sponsor: Ellipses Pharma

Sex: All·Age: 18+

Code: NCT05443126·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

for Solid Malignancies

Sites in Los Angeles, Duarte +15 more locations

Sponsor: Immunome, Inc.

Sex: All·Age: 18+

Code: NCT06823167·Phase 1·Recruiting·Listed Feb 2025

Apply to this trial