Paid Clinical Trials in California

California has 6,346 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 8, 2026.

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5,270 clinical trials

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Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

Sites in Palo Alto, Oakland +10 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT06332534·Phase 3·Recruiting·Listed Mar 2024

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Hydrus® Microstent New Enrollment Post-Approval Study

for Primary Open Angle Glaucoma

Sites in Sacramento +19 more locations

Sponsor: Alcon Research

Sex: All·Age: 45+

Code: NCT04553523·Recruiting·Listed Sep 2020

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The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

Sites in Torrance +14 more locations

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting·Listed Sep 2023

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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

Sites in Los Angeles, San Francisco +20 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting·Listed Mar 2023

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Sacramento +22 more locations

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting·Listed Aug 2024

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XTX301 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Sacramento +9 more locations

Sponsor: Xilio Development, Inc.

Sex: All·Age: 18+

Code: NCT05684965·Phase 1, Phase 2·Recruiting·Listed Jan 2023

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SPEARHEAD-3 Pediatric Study

for Synovial Sarcoma

Sites in Palo Alto +9 more locations

Sponsor: USWM CT, LLC

Sex: All·Age: 2 - 21

Code: NCT05642455·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for Glioblastoma (GBM)

Sites in San Francisco, Duarte +15 more locations

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT06805305·Phase 2·Recruiting·Listed Feb 2025

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A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

for Acute Myeloid Leukemia

Sites in Sacramento, Duarte +6 more locations

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 12 - 78

Code: NCT03802695·Phase 1·Recruiting·Listed Jan 2019

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Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)

for Multiple Myeloma

Drug: Elranatamab

Sites in Orange, Irvine +15 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06057402·Phase 4·Recruiting·Listed Sep 2023

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Study of XB010 in Subjects With Solid Tumors

for Locally Advanced or Metastatic Solid Tumors

Sites in Los Angeles, Irvine +14 more locations

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06545331·Phase 1·Recruiting·Listed Aug 2024

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A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sites in Sacramento, La Jolla +22 more locations

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06706076·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for Myelofibrosis

Sites in Los Angeles, San Francisco +22 more locations

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT05320198·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

for NSCLC Stage IV

Sites in Fountain Valley, El Segundo +15 more locations

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 90

Code: NCT06745908·Phase 3·Recruiting·Listed Dec 2024

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A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

for Acute Pancreatitis

Sites in Los Angeles +9 more locations

Sponsor: Panafina, Inc.

Sex: All·Age: 18 - 85

Code: NCT06080789·Phase 2·Recruiting·Listed Oct 2023

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Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in San Francisco, Newport Beach +8 more locations

Sponsor: Ensem Therapeutics

Sex: All·Age: 18+

Code: NCT06993844·Phase 1, Phase 2·Recruiting·Listed May 2025

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A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

for Advanced Solid Tumor

Drug: NXP900

Sites in La Jolla +12 more locations

Sponsor: Nuvectis Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05873686·Phase 1·Recruiting·Listed May 2023

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KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

for Solid Tumors With HRAS Alterations

Sites in Los Angeles +21 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06026410·Phase 1·Recruiting·Listed Sep 2023

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Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

for Myasthenia Gravis

Sites in Irvine +8 more locations

Sponsor: NMD Pharma A/S

Sex: All·Age: 18+

Code: NCT06414954·Phase 2·Recruiting·Listed May 2024

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A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

for Ulcerative Colitis

Sites in San Francisco, Loma Linda +18 more locations

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT05287126·Phase 2·Recruiting·Listed Mar 2022

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A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

for Solid Tumor Malignancies

Sites in Los Angeles, La Jolla +11 more locations

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT07207707·Phase 1·Recruiting·Listed Oct 2025

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VTP-1000 in Adults With Celiac Disease

for Celiac Disease

Sites in Los Angeles +15 more locations

Sponsor: Barinthus Biotherapeutics

Sex: All·Age: 18 - 70

Code: NCT06310291·EARLY_Phase 1·Recruiting·Listed Mar 2024

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Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

for Overactive Bladder (OAB)

Sites in Los Angeles, San Diego +13 more locations

Sponsor: FemPulse Corporation

Sex: Female·Age: 21+

Code: NCT07195656·Recruiting·Listed Sep 2025

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A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee

for Chondral Defect

Sites in Palo Alto, Sacramento +9 more locations

Sponsor: Vericel Corporation

Sex: All·Age: 10 - 17

Code: NCT03588975·Phase 3·Recruiting·Listed Jul 2018

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A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

for Alzheimer Disease

Drug: LY4006895

Sites in Los Alamitos +10 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 45 - 85·Accepts healthy volunteers

Code: NCT06657768·Phase 1·Recruiting·Listed Oct 2024

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HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

for Degenerative Disc Disease (DDD)

Sites in Walnut Creek, Santa Monica +12 more locations

Sponsor: ReGelTec, Inc.

Sex: All·Age: 22 - 85

Code: NCT06011551·Recruiting·Listed Aug 2023

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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for Uncontrolled Hypertension

Sites in San Jose, West Hills +20 more locations

Sponsor: Retension Pharmaceuticals. Inc.

Sex: All·Age: 18 - 70

Code: NCT07142356·Phase 2·Recruiting·Listed Aug 2025

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Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV)

for Non-small Cell Lung Cancer (NSCLC)

Sites in Los Angeles, Orange +10 more locations

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT07154706·Phase 3·Recruiting·Listed Sep 2025

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A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

for Non-small Cell Lung Cancer

Drug: Calderasib

Sites in Beverly Hills, Bakersfield +11 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06345729·Phase 3·Recruiting·Listed Apr 2024

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Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

for Pancreatic Cancer

Sites in Los Angeles +12 more locations

Sponsor: Alpha Tau Medical LTD.

Sex: All·Age: 18 - 120

Code: NCT06698458·Recruiting·Listed Nov 2024

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A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for Non-Squamous Non-Small Cell Lung Cancer

Drug: Osimertinib

Sites in Los Angeles, Newport Beach +11 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07005102·Phase 2, Phase 3·Recruiting·Listed Jun 2025

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Single and Multiple Ascending Dose Study of AMG 513 in Participants With Obesity

for Cardiometabolic Disease

Sites in Anaheim, Oxnard +8 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06585462·Phase 1·Recruiting·Listed Sep 2024

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A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

for Ulcerative Colitis

Sites in Palo Alto, Orange +12 more locations

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT06405087·Phase 3·Recruiting·Listed May 2024

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Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

for Regional Citrate Anticoagulation (RCA)

Sites in Los Angeles +7 more locations

Sponsor: Vantive Health LLC

Sex: All·Age: 18+

Code: NCT05399537·Phase 3·Recruiting·Listed Jun 2022

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A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

for Chronic Lymphocytic Leukemia (CLL)

Sites in San Francisco, Duarte +13 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05131022·Phase 1·Recruiting·Listed Nov 2021

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This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.

for Peripheral Nerve Injury Upper Limb

Sites in Los Angeles +23 more locations

Sponsor: Neuraptive Therapeutics Inc.

Sex: All·Age: 18 - 80

Code: NCT06616025·Phase 3·Recruiting·Listed Sep 2024

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A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)

for Gram-negative Bacterial Infection

Sites in Orange +10 more locations

Sponsor: Pfizer

Sex: All·Age: Up to 39 Weeks

Code: NCT06462235·Phase 2·Recruiting·Listed Jun 2024

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A Study of Zasocitinib in Adults With Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Zasocitinib

Sites in Fountain Valley +14 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07244263·Phase 2·Recruiting·Listed Nov 2025

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Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

for Prostate Cancer

Sites in Orange, Santa Monica +22 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05803941·Phase 4·Recruiting·Listed Apr 2023

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MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

for Recurrent Melanoma (Skin)

Drug: Nivolumab

Sites in Orange +11 more locations

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05655312·Phase 1, Phase 2·Recruiting·Listed Dec 2022

Apply to this trial