Paid Clinical Trials in California

California has 6,346 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 8, 2026.

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5,270 clinical trials

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Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)

for Chronic Neuropathic Pain

Sites in La Jolla +10 more locations

Sponsor: Sangamo Therapeutics

Sex: All·Age: 18+

Code: NCT06980948·Phase 1, Phase 2·Recruiting·Listed May 2025

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A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A

for Haemophilia A

Sites in Los Angeles +11 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: All ages

Code: NCT05685238·Phase 3·Recruiting·Listed Jan 2023

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A Study of PYX-201 in Advanced Solid Tumors

for Solid Tumor

Sites in Los Angeles +16 more locations

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT05720117·Phase 1·Recruiting·Listed Feb 2023

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Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

for Advanced Melanoma

Sites in Los Angeles, Santa Rosa +9 more locations

Sponsor: Eikon Therapeutics

Sex: All·Age: 18+

Code: NCT06697301·Phase 2, Phase 3·Recruiting·Listed Nov 2024

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ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

Sites in Los Angeles, San Francisco +12 more locations

Sponsor: Zenith Epigenetics

Sex: Male·Age: 18+

Code: NCT04986423·Phase 2·Recruiting·Listed Aug 2021

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A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors

for Urothelial Carcinoma Bladder

Sites in Duarte, Irvine +10 more locations

Sponsor: Aktis Oncology, Inc.

Sex: All·Age: 18+

Code: NCT07020117·Phase 1·Recruiting·Listed Jun 2025

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Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

for Metastatic Uveal Melanoma

Sites in Los Angeles +6 more locations

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT03947385·Phase 1, Phase 2·Recruiting·Listed May 2019

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Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting·Listed Oct 2018

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A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

for Pemphigus Vulgaris

Sites in Sacramento, Redwood City +8 more locations

Sponsor: Cabaletta Bio

Sex: All·Age: 18+

Code: NCT04422912·Phase 1, Phase 2·Recruiting·Listed Jun 2020

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To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

for Peripheral T Cell Lymphoma

Sites in Santa Monica, Clovis +7 more locations

Sponsor: Acrotech Biopharma Inc.

Sex: All·Age: 18+

Code: NCT06072131·Phase 3·Recruiting·Listed Oct 2023

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Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

for Familial Adenomatous Polyposis (FAP)

Sites in Arcadia +17 more locations

Sponsor: Rapamycin Holdings Inc.

Sex: All·Age: 18+

Code: NCT06950385·Phase 3·Recruiting·Listed Apr 2025

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A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine

for Migraine

Sites in Los Angeles, La Jolla +11 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 70

Code: NCT06602479·Phase 2·Recruiting·Listed Sep 2024

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A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for Locally Advanced Solid Tumor

Sites in Sacramento, Orange +18 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05384626·Phase 1, Phase 2·Recruiting·Listed May 2022

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A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

for Crohn's Disease

Drug: Upadacitinib

Sites in Los Angeles, La Jolla +7 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06227910·Phase 3·Recruiting·Listed Jan 2024

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Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

Sites in Sacramento, Duarte +17 more locations

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting·Listed Jan 2019

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STOP-HAE: A Phase 3 Study of ADX-324 in HAE

for Hereditary Angioedema

Sites in San Diego, Walnut Creek +13 more locations

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06960213·Phase 3·Recruiting·Listed May 2025

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Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)

for Nausea

Sites in Los Angeles, San Francisco +10 more locations

Sponsor: Enterra Medical, Inc.

Sex: All·Age: 18+

Code: NCT06464926·Recruiting·Listed Jun 2024

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A Study to Evaluate Safety and Effectiveness of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Improvement of Mid-Face Volume

for Mid Face Volume Deficit

Sites in San Diego +14 more locations

Sponsor: AbbVie

Sex: All·Age: 22+

Code: NCT06734351·Phase 3·Recruiting·Listed Dec 2024

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EFS of the DUO System for Tricuspid Regurgitation

for Tricuspid Regurgitation

Sites in Thousand Oaks +11 more locations

Sponsor: CroiValve Limited

Sex: All·Age: 18+

Code: NCT05913908·Recruiting·Listed Jun 2023

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Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

for Focal Segmental Glomerulosclerosis

Drug: Sparsentan

Sites in Los Angeles +16 more locations

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 17

Code: NCT05003986·Phase 2·Recruiting·Listed Aug 2021

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A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

for Advanced Hepatocellular Carcinoma

Sites in Los Angeles, La Jolla +13 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06600321·Phase 1·Recruiting·Listed Sep 2024

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A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

for LGLL - Large Granular Lymphocytic Leukemia

Sites in Duarte, Irvine +13 more locations

Sponsor: Dren Bio

Sex: All·Age: 18+

Code: NCT05475925·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.

for Infertility (IVF Patients)

Sites in Encino +15 more locations

Sponsor: Granata Bio Corporation

Sex: Female·Age: 18 - 42

Code: NCT07216742·Phase 3·Recruiting·Listed Oct 2025

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A Study to Learn About a Vaccine Against E Coli in Healthy Adults

for Healthy Participants

Sites in Walnut Creek, Anaheim +9 more locations

Sponsor: Pfizer

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT07122986·Phase 1·Recruiting·Listed Aug 2025

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Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

for Acute Ischemic Stroke

Sites in Oxnard, Carmichael +12 more locations

Sponsor: Pharmazz, Inc.

Sex: All·Age: 18 - 80

Code: NCT05691244·Phase 3·Recruiting·Listed Jan 2023

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A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

for Spinal Muscular Atrophy

Drug: Apitegromab

Sites in Palo Alto, Orange +12 more locations

Sponsor: Scholar Rock, Inc.

Sex: All·Age: Up to 2

Code: NCT07047144·Phase 2·Recruiting·Listed Jul 2025

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ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

for Refractory Cancer

Drug: Nivolumab

Sites in Stanford +12 more locations

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT03686124·Phase 1, Phase 2·Recruiting·Listed Sep 2018

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Prospective, Open-label, Non-significant Risk, Multicenter Study Comparing the Polyp Detection of the Study Device to That of the Colonoscopy Reference

for Colonic Polyps

Sites in Orange, Lancaster +9 more locations

Sponsor: Capso Vision, Inc.

Sex: All·Age: 45 - 75

Code: NCT07089615·Recruiting·Listed Jul 2025

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A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

for Primary Myelofibrosis

Sites in Palo Alto +12 more locations

Sponsor: Ajax Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06343805·Phase 1·Recruiting·Listed Apr 2024

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OssDsign® Spine Registry Study ("Propel")

for Degenerative Disc Disease

Sites in Long Beach, Fresno +6 more locations

Sponsor: OssDsign

Sex: All·Age: 21+

Code: NCT05329129·Recruiting·Listed Apr 2022

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A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

for Melanoma

Drug: Cemiplimab

Sites in Los Angeles, San Francisco +9 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06413680·Phase 1, Phase 2·Recruiting·Listed May 2024

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Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

for Cystic Fibrosis

Sites in Los Angeles +11 more locations

Sponsor: Arcturus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06747858·Phase 2·Recruiting·Listed Dec 2024

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A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

for Solid Tumor

Sites in Los Angeles +14 more locations

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06586957·Phase 1·Recruiting·Listed Sep 2024

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A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

for Advanced Solid Tumors Cancer

Sites in Los Angeles +9 more locations

Sponsor: Nimbus Wadjet, Inc.

Sex: All·Age: 18 - 99

Code: NCT06898450·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

for Parkinson Disease

Drug: LY4006896

Sites in Los Alamitos +10 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 30 - 85·Accepts healthy volunteers

Code: NCT06809400·Phase 1·Recruiting·Listed Feb 2025

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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

for Ulcerative Colitis

Sites in San Diego +7 more locations

Sponsor: Takeda

Sex: All·Age: 2+

Code: NCT05442567·Phase 3·Recruiting·Listed Jul 2022

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An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for Advanced Solid Tumors

Sites in Los Angeles +9 more locations

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 18+

Code: NCT06480552·Phase 1·Recruiting·Listed Jun 2024

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A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

for Solid Tumor

Sites in Palo Alto +4 more locations

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT04300556·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

for Advanced Cancer

Sites in Los Angeles +14 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05557045·Phase 1·Recruiting·Listed Sep 2022

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A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for Pancreatic Ductal Adenocarcinoma

Sites in Los Angeles +12 more locations

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07020221·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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