Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor

for Upper Limb Essential Tremor

Sites in Fresno +2 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 85

Code: NCT07673107·Phase 2·Recruiting·Listed Jun 29, 2026

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Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients

for Migraine

Sites in Walnut Creek +5 more locations

Sponsor: Aspeya, Inc.

Sex: All·Age: 18 - 65

Code: NCT07646613·Phase 2·Recruiting·Listed Jun 15, 2026

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Renal Impairment Study for Oral EC5026

for Chronic Kidney Disease

1 location in Sacramento

Sponsor: EicOsis Human Health Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07694544·Phase 1·Recruiting·Listed Jul 10, 2026

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MiniMed Fit Payload Wear Pediatric Study

for Diabetes (DM)

Sites in Sacramento, Santa Barbara +3 more locations

Sponsor: Medtronic MiniMed, Inc.

Sex: All·Age: 7 - 17

Code: NCT07675161·Recruiting·Listed Jun 30, 2026

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A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)

for Lipoprotein(a)

Sites in Beverly Hills, Lincoln +10 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07614984·Phase 2·Recruiting·Listed May 29, 2026

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A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia

for Schizophrenia

Sites in Garden Grove +7 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 55

Code: NCT07615426·Phase 1·Recruiting·Listed May 29, 2026

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Phase 1 Study Evaluating Safety and Pharmacokinetics of ASY202 in Adults With Asthma

for Safety in Asthma Patients

Sites in Anaheim +2 more locations

Sponsor: Aspeya, Inc.

Sex: All·Age: 18 - 55

Code: NCT07665892·Phase 1·Recruiting·Listed Jun 24, 2026

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CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life

for Premenstrual Syndrome

1 location in San Francisco

Sponsor: Samphire Group, Inc.

Sex: Female·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07679074·Recruiting·Listed Jul 1, 2026

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Optimizing Extended-Duration (XD-) TOMAC Therapy for Restless Legs Syndrome (RLS)

for Restless Legs Syndrome (RLS)

1 location in Pleasanton

Sponsor: Noctrix Health, Inc.

Sex: All·Age: 21+

Code: NCT07675109·Recruiting·Listed Jun 30, 2026

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A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects

for Health Adult Subjects

1 location in Chula Vista

Sponsor: TIXiMED, Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07675590·Phase 1·Recruiting·Listed Jun 30, 2026

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A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

for Colorectal Cancer

Sites in Los Angeles +4 more locations

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07659795·Phase 2·Recruiting·Listed Jun 22, 2026

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A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

for Acute Treatment of Migraine

Drug: Rimegepant

Sites in Canoga Park +6 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07609914·Phase 4·Recruiting·Listed May 2026

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A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure

for Pneumonia

Sites in San Francisco +2 more locations

Sponsor: MiNK Therapeutics

Sex: All·Age: 18+

Code: NCT07615010·Phase 2·Recruiting·Listed May 29, 2026

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kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot

for Stroke

1 location in San Francisco

Sponsor: Magnetic Tides

Sex: All·Age: 18 - 80

Code: NCT07631078·Recruiting·Listed Jun 5, 2026

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A Study of TAK-360 in Adults With Narcolepsy Type 1 (Narcolepsy With Cataplexy)

for Narcolepsy Type 1

Sites in Redwood City +2 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT07633301·Phase 2·Recruiting·Listed Jun 8, 2026

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A Comprehensive Digital Care Program for Migraine Management

for Migraine

1 location in San Francisco

Sponsor: Hinge Health, Inc

Sex: All·Age: 18+

Code: NCT07642414·Recruiting·Listed Jun 11, 2026

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A Study to Assess the Adverse Events and How Bretisilocin Intramuscular Injection Moves Through the Body of Healthy Adult Participants

for Healthy Volunteer

1 location in Los Alamitos

Sponsor: AbbVie

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07604558·Phase 1·Recruiting·Listed May 2026

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The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment

for Pregnant Individuals

Sites in West Covina +5 more locations

Sponsor: BillionToOne Inc.

Sex: Female·Age: All ages

Code: NCT07643896·Recruiting·Listed Jun 12, 2026

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Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications

for Negative Symptoms of Schizophrenia

Sites in Culver City +4 more locations

Sponsor: Minerva Neurosciences

Sex: All·Age: 18 - 55

Code: NCT07565428·Phase 3·Recruiting·Listed May 2026

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A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

for Major Depressive Disorder (MDD)

Sites in Lafayette +10 more locations

Sponsor: Draig Therapeutics Ltd

Sex: All·Age: 18 - 75

Code: NCT07610473·Phase 2·Recruiting·Listed May 28, 2026

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Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer

for HR+ HER2- Breast Cancer

Sites in Los Angeles +6 more locations

Sponsor: Faeth Therapeutics

Sex: All·Age: 18+

Code: NCT07558733·Phase 1, Phase 2·Recruiting·Listed Apr 2026

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A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

for Castration Resistant Metastatic Prostate Cancer

Sites in Irvine +3 more locations

Sponsor: Aktis Oncology, Inc.

Sex: Male·Age: 18+

Code: NCT07581184·Phase 1·Recruiting·Listed May 2026

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A Long-Term Observational Study of Patients With Fucosidosis

for Fucosidosis

Sites in Orange +1 more location

Sponsor: JCR Pharmaceuticals Co., Ltd.

Sex: All·Age: All ages

Code: NCT07615400·Recruiting·Listed May 29, 2026

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A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)

for LMNA-Related Dilated Cardiomyopathy

Sites in Los Angeles +5 more locations

Sponsor: Nuevocor Pte. Ltd.

Sex: All·Age: 18+

Code: NCT07606274·Phase 1, Phase 2·Recruiting·Listed May 2026

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A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

for Advanced NRAS-Mutant Melanoma

Sites in Los Angeles, San Francisco +7 more locations

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07584226·Phase 1·Recruiting·Listed May 2026

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An Open-label Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

for Phelan-McDermid Syndrome

Sites in San Rafael +1 more location

Sponsor: Neuren Pharmaceuticals Limited

Sex: All·Age: 3 - 12

Code: NCT07593391·Phase 3·Recruiting·Listed May 2026

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Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity

for Overweight or Obesity

1 location in Glendale

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07594093·Phase 1·Recruiting·Listed May 2026

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Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

for Focal Seizure

Sites in Palmdale +3 more locations

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT07563881·Phase 3·Recruiting·Listed May 2026

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A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation

for Non-small Cell Lung Cancer (NSCLC)

Sites in Glendale +2 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07566052·Phase 3·Recruiting·Listed May 2026

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A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy

for Diabetic Retinopathy

1 location in Glendale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07588100·Phase 1·Recruiting·Listed May 2026

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A Post-Market Assessment of the Safety and Performance of the TriClip™ System

for Tricuspid Regurgitation (TR)

Sites in La Jolla +1 more location

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07586995·Recruiting·Listed May 2026

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Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for Multiple Myeloma

Sites in Duarte, Irvine +4 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07555938·Phase 3·Recruiting·Listed Apr 2026

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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

Sites in Anaheim, Chula Vista +4 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07577843·Phase 3·Recruiting·Listed May 2026

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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis

for Colitis, Ulcerative

Sites in Anaheim, Chula Vista +5 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07577856·Phase 3·Recruiting·Listed May 2026

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Phase 1 Study of C.001 in Retinal Degeneration

for Geographic Atrophy

1 location in Beverly Hills

Sponsor: Cellio Therapeutics Inc

Sex: All·Age: 18+

Code: NCT07594236·Phase 1·Recruiting·Listed May 2026

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An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

for Hypertension (HTN)

Drug: QCZ484

Sites in Los Angeles, Garden Grove +7 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07543120·Phase 2·Recruiting·Listed Apr 2026

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EXACT Study: A Blinded Study in Patients With Alport Syndrome to Evaluate Exaluren Efficacy and Safety

for Alport Syndrome, X-Linked

Sites in Los Angeles, Stanford +6 more locations

Sponsor: Eloxx Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07523581·Phase 2·Recruiting·Listed Apr 2026

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NORM-HF Pivotal Study

for Heart Failure

Sites in Chula Vista +2 more locations

Sponsor: Foundry Innovation & Research 1, Limited (FIRE1)

Sex: All·Age: 18+

Code: NCT07574593·Recruiting·Listed May 2026

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A Study of LY4005130 in Adult Participants With Severe Alopecia Areata (Hair Loss)

for Alopecia Areata

Drug: LY4005130

Sites in Fremont, Northridge +7 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 50

Code: NCT07533006·Phase 2·Recruiting·Listed Apr 2026

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Preventing Medication Mismanagement in People Living With Dementia

for Dementia

1 location in Folsom

Sponsor: HiDO Technologies

Sex: All·Age: 65+

Code: NCT07600684·Recruiting·Listed May 2026

Apply to this trial