Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or OTX-TKI-2023-AMD-303 Study

for Neovascular Age-Related Macular Degeneration (nAMD)

Sites in Santa Barbara, Bakersfield +6 more locations

Sponsor: Ocular Therapeutix, Inc.

Sex: All·Age: 50+

Code: NCT07516132·Phase 3·Recruiting·Listed Apr 2026

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A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

for Asthma

Sites in Newport Beach, Walnut Creek +49 more locations

Sponsor: Sanofi

Sex: All·Age: 6+

Code: NCT07556159·Recruiting·Listed Apr 2026

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A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran

for Hypertension

Drug: Zilebesiran

Sites in Lake Forest +2 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT07553442·Phase 2·Recruiting·Listed Apr 2026

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A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States

for Advanced Unresectable Gastric Adenocarcinoma

Sites in Los Angeles +5 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07554521·Phase 2·Recruiting·Listed Apr 2026

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A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation

for Advanced/Metastatic Colorectal Adenocarcinoma

Drug: BAY 3771249

Sites in San Diego, Duarte +5 more locations

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT07535112·Phase 1·Recruiting·Listed Apr 2026

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A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity

for Obesity

Drug: NNC0113-5840

1 location in Glendale

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18 - 55

Code: NCT07566390·Phase 1·Recruiting·Listed May 2026

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A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating

for IBS (Irritable Bowel Syndrome)

1 location in Los Angeles

Sponsor: Kiwi Health Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07591584·Recruiting·Listed May 2026

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A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Sites in Pasadena, Coronado +3 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT07527910·Phase 2·Recruiting·Listed Apr 2026

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A Study of JADE101 in Participants With Immunoglobulin A Nephropathy

for IgA Nephropathy

Sites in Chula Vista +5 more locations

Sponsor: Jade Biosciences, Inc.

Sex: All·Age: 18 - 60

Code: NCT07541287·Phase 2·Recruiting·Listed Apr 2026

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A Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

for CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy)

Sites in Rancho Mirage +6 more locations

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18+

Code: NCT07540221·Phase 3·Recruiting·Listed Apr 2026

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A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

for Colorectal Cancer

Sites in Duarte +2 more locations

Sponsor: Dispatch Biotherapeutics

Sex: All·Age: 18+

Code: NCT07544589·Phase 1·Recruiting·Listed Apr 2026

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Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

for Breast Cancer

Sites in Los Angeles +4 more locations

Sponsor: Regor Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07524322·Phase 1·Recruiting·Listed Apr 2026

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Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

for Opioid-Induced Respiratory Depression

Sites in San Francisco +1 more location

Sponsor: NeurOptics Inc

Sex: All·Age: 3 - 17·Accepts healthy volunteers

Code: NCT07573150·Recruiting·Listed May 2026

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An Open Label Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on GI Health and Related Health Outcomes

for Health

1 location in Del Mar

Sponsor: PepsiCo Global R&D

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT07563855·Recruiting·Listed May 2026

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Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

for Myotonic Dystrophy Type 1 (DM1)

Sites in La Jolla +6 more locations

Sponsor: Dyne Therapeutics

Sex: All·Age: 16+

Code: NCT07486934·Phase 3·Recruiting·Listed Mar 2026

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A Single Dose, Phase 1 Study of JADE101 in Healthy Japanese and Chinese Participants

for Healthy Volunteers (HV)

1 location in Glendale

Sponsor: Jade Biosciences, Inc.

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07525947·Phase 1·Recruiting·Listed Apr 2026

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A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis

for Moderate to Severe Atopic Dermatitis

Sites in Fremont +5 more locations

Sponsor: Sitryx Therapeutics Ltd

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07558668·Phase 1·Recruiting·Listed Apr 2026

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Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia

for RPS19 Deficient Diamond-Blackfan Anemia

Sites in Stanford +1 more location

Sponsor: Apriligen, Inc.

Sex: All·Age: 2 - 25

Code: NCT07476183·Phase 1·Recruiting·Listed Mar 2026

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Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

for Solid Tumor

Sites in Los Angeles +2 more locations

Sponsor: Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07517198·Phase 1·Recruiting·Listed Apr 2026

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Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

for Acute Promyelocytic Leukemia (APL)

Sites in Los Angeles, Duarte +7 more locations

Sponsor: Quetzal Therapeutics

Sex: All·Age: 18 - 71

Code: NCT07504458·Phase 3·Recruiting·Listed Mar 2026

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A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU)

for Angiokeratomas

Sites in Sherman Oaks +3 more locations

Sponsor: Palvella Therapeutics, Inc.

Sex: All·Age: 6+

Code: NCT07552077·Phase 2·Recruiting·Listed Apr 2026

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Generative AI Plan for Care Lab Study

for Primary Health Care

1 location in Mountain View

Sponsor: Fitbit LLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07552311·Recruiting·Listed Apr 2026

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Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

for Relapsed or Refractory Large B-cell Lymphoma

Sites in Duarte, Stanford +4 more locations

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT07479797·Phase 3·Recruiting·Listed Mar 2026

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Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

for Schizophrenia

Drug: GXV813

Sites in Pico Rivera +6 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07467993·Phase 2·Recruiting·Listed Mar 2026

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Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for Lung Cancer

Sites in Duarte, Newport Beach +6 more locations

Sponsor: Vergent Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT07499674·Phase 3·Recruiting·Listed Mar 2026

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Radicle Revive™: A Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Associated Health Outcomes and Related Health Outcomes

for Cognitive Function

1 location in Del Mar

Sponsor: Radicle Science

Sex: Female·Age: 40 - 105·Accepts healthy volunteers

Code: NCT07548307·Recruiting·Listed Apr 2026

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ROME GS System Study

for Diabetes

Sites in Walnut Creek, Escondido +2 more locations

Sponsor: Senseonics, Inc.

Sex: All·Age: 18+

Code: NCT07518004·Recruiting·Listed Apr 2026

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A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

for Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS)

Drug: NIO752

Sites in San Francisco +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 41 - 81

Code: NCT07498426·Phase 3·Recruiting·Listed Mar 2026

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A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

for Epidermal Growth Factor

Sites in Los Angeles +5 more locations

Sponsor: EpiBiologics

Sex: All·Age: 18+

Code: NCT07462377·Phase 1·Recruiting·Listed Mar 2026

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Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.

for Acne Vulgaris

1 location in Sacramento

Sponsor: Integrative Skin Science and Research

Sex: All·Age: 9+·Accepts healthy volunteers

Code: NCT07544251·Phase 4·Recruiting·Listed Apr 2026

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A Decentralized Clinical Study Evaluating the Effectiveness of Two Different Doses of MyCondro™ on Physical Mobility and Joint Health

for Joint Health

1 location in Los Angeles

Sponsor: Lesaffre International

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT07493239·Recruiting·Listed Mar 2026

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Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

for Netherton Syndrome

Sites in Fremont +4 more locations

Sponsor: Quoin Pharmaceuticals

Sex: All·Age: 4+

Code: NCT07538583·Phase 2, Phase 3·Recruiting·Listed Apr 2026

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A Study to Assess How Intravenous and Subcutaneous Administrations of Risankizumab Moves Through the Body of Healthy Adult Participants

for Healthy Volunteer

Drug: Risankizumab

Sites in Anaheim +1 more location

Sponsor: AbbVie

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07466550·Phase 1·Recruiting·Listed Mar 2026

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Study to Evaluate the Efficacy and Safety of BMN 333 Versus Vosoritide in Children With Achondroplasia

for Achondroplasia

Drug: Vosoritide

Sites in Oakland +8 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 17

Code: NCT07441876·Phase 2, Phase 3·Recruiting·Listed Mar 2026

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Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

for PTSD

1 location in Sunnyvale

Sponsor: Acacia Clinics

Sex: All·Age: 18 - 70

Code: NCT07523685·Recruiting·Listed Apr 2026

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Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer

for Bladder (Urothelial, Transitional Cell) Cancer

Sites in Bakersfield +4 more locations

Sponsor: Protara Therapeutics

Sex: All·Age: 18+

Code: NCT07480356·Phase 3·Recruiting·Listed Mar 2026

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A Study to Assess Adverse Events, Tolerability, and Pharmacokinetics of Subcutaneous Injections of ABBV-295 in Healthy Adult Japanese Participants With Overweight or Obesity.

for Healthy Volunteer

1 location in Anaheim

Sponsor: AbbVie

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07514260·Phase 1·Recruiting·Listed Apr 2026

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A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus (T2DM)

1 location in Chula Vista

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07465224·Phase 2·Recruiting·Listed Mar 2026

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A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

for Colitis Ulcerative

Sites in Anaheim +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 75

Code: NCT07463183·Phase 2·Recruiting·Listed Mar 2026

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Study of Intrathecal ELP-02 for Charcot-Marie-Tooth Disease Type 4J (CMT4J)

for Charcot-Marie-Tooth Disease Type 4J

Sites in Palo Alto +1 more location

Sponsor: Elpida Therapeutics SPC

Sex: All·Age: 3 - 20

Code: NCT07447557·Phase 1, Phase 2·Recruiting·Listed Mar 2026

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